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CTRI Number  CTRI/2025/12/098725 [Registered on: 10/12/2025] Trial Registered Prospectively
Last Modified On: 08/12/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   Improving IBS Symptoms in Working Professionals Through Individualized Homeopathy 
Scientific Title of Study   UTILITY OF INDIVIDUALIZED HOMOEOPATHIC MEDICINE SELECTED USING KENT REPERTORY IN MANAGING PATIENTS OF IRRITABLE BOWEL SYNDROME HAVING OCCUPATIONAL STRESS 
Trial Acronym  None 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr VANDANA NARESH KHEMANI 
Designation  PG Scholar 
Affiliation  Jawaharlal Nehru Homoeoopathic Medical College and Hospital  
Address  OPD Room number 110, Jawaharlal Nehru Homoeopathic Medical College and Hospital Parul University, Waghodia

Vadodara
GUJARAT
391760
India 
Phone  7069676384  
Fax    
Email  vandanakhemani0701@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Jigneshkumar Patel  
Designation  BHMS, MD Homoeopathy, HOD ( Homoeoopathic Repertory and Case taking 
Affiliation  Jawaharlal Nehru Homoeoopathic Medical College and Hospital  
Address  Department of Homoeoopathic Repertory and Case taking, Jawaharlal Nehru Homoeopathic Medical College and Hospital Parul University, Waghodia

Vadodara
GUJARAT
391760
India 
Phone  9909949221  
Fax    
Email  jignesh.patel79013@paruluniversity.ac.in  
 
Details of Contact Person
Public Query
 
Name  Dr VANDANA NARESH KHEMANI 
Designation  Pg scholar  
Affiliation  Jawaharlal Nehru Homoeoopathic Medical College and Hospital  
Address  OPD Room number 110, Jawaharlal Nehru Homoeopathic Medical College and Hospital Parul University, Waghodia

Vadodara
GUJARAT
391760
India 
Phone  7069676384  
Fax    
Email  vandanakhemani0701@gmail.com  
 
Source of Monetary or Material Support  
Jawaharlal Nehru Homoeopathic Medical College and Hospital, Parul University, Waghodiya. Vadodara, Gujarat. 391760 
 
Primary Sponsor  
Name  Jawaharlal Nehru Homoeopathic Medical College and Hospital Parul University  
Address  Jawaharlal Nehru Homoeopathic Medical College and Hospital, Parul University, Waghodia, Vadodara, Gujarat, India, 391760 
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr VANDANA NARESH KHEMANI  Jawaharlal Nehru Homoeopathic Medical College and Hospital, Parul University   OPD Room number 110, Jawaharlal Nehru Homoeopathic Medical College and Hospital, Parul University, Waghodia Vadodara GUJARAT
Vadodara
GUJARAT 
7069676384

vandanakhemani0701@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Jawaharlal Nehru Homoeopathic Medical College and Hospital   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: K58||Irritable bowel syndrome,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Individualised Homoeopathic Medicine   Individualised Homoeopathic Medicine selected by Homoeoopathic cardinal principles for 4 months in each patient  
Comparator Agent  No comparator agent  As this is single arm study 
 
Inclusion Criteria  
Age From  22.00 Year(s)
Age To  50.00 Year(s)
Gender  Both 
Details  - Patients aged 22-50 years, Having occupational stress of mild range assessed through WSS ( workplace stress scale )
- Patients diagnosed with irritable bowel syndrome (IBS) as per Rome IV criteria.
- Patients who give written informed consent 
 
ExclusionCriteria 
Details  - Patients with organic gastrointestinal diseases (e.g., inflammatory bowel disease, celiac disease, malignancy).
- Patients with uncontrolled systemic illnesses (e.g., diabetes, hypertension, renal/liver failure).
- Patients currently on other long-term treatment for IBS
- Pregnant and lactating women. 
 
Method of Generating Random Sequence    
Method of Concealment    
Blinding/Masking    
Primary Outcome  
Outcome  TimePoints 
Mild improvement
Moderate improvement
Clinically significant improvement
Status quo / negligible or no improvement
Any increase in IBS-SSS or WSS score will be counted as worse  
6 months 
 
Secondary Outcome  
Outcome  TimePoints 
Nil   Nil 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Irritable Bowel Syndrome IBS is a chronic functional gastrointestinal disorder affecting about 4.1 percent of the global population and 4.2 to 7.5 percent of people in India. It causes abdominal pain, disturbed bowel habits, reduced quality of life, and lower work productivity. Research shows a strong link between IBS and psychological factors such as stress, anxiety, and occupational pressure.
Homeopathy has shown promising results in managing chronic functional disorders like IBS, especially when the treatment is individualized. Previous studies have reported significant improvement when remedies are selected based on the totality of symptoms. However, very few studies have used Kents Repertory in a structured way, particularly for patients with stress related or occupation related IBS.
This study aims to evaluate the usefulness of individualized homoeopathic medicines selected through Kent repertory in patients suffering from IBS with occupational stress. It also aims to study the relationship between IBS severity and work stress levels and to compare IBS SSS and Work Stress Scale scores before and after treatment. Patients will be assessed every 15 days over a period of four months to observe progressive changes.
The study hopes to provide evidence for an integrated homeopathic approach in psychosomatic conditions by combining repertorial analysis, individualized prescribing, and stress assessment.
 
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