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CTRI Number  CTRI/2025/12/099608 [Registered on: 22/12/2025] Trial Registered Prospectively
Last Modified On: 20/12/2025
Post Graduate Thesis   
Type of Trial  Interventional 
Type of Study   Drug
Surgical/Anesthesia
Preventive 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Comparison of Ultrasound-Guided Femoral and Pericapsular Nerve Block Techniques for Pain Relief After Hip Fracture Surgery 
Scientific Title of Study   Comparing the efficacy of ultrasound guided combined lateral femoral cutaneous nerve block and femoral nerve block with pericapsular nerve block for post operative analgesia in patients undergoing hip fracture surgeries using levobupivacaine:A prospective randomized study 
Trial Acronym  Nil 
Secondary IDs if Any  
Secondary ID  Identifier 
Nil  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  DrJasni K B 
Designation  junior resident 
Affiliation  Rajarajeswari medical college and hospital  
Address  Rajarajeswari medical college and hospital kengeri satellite town kambipura Bangalore

Bangalore
KARNATAKA
560074
India 
Phone  9538808087  
Fax    
Email  jasnibasheer97@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  DrKarthik G S  
Designation  professor and HOD of department of Anaesthesiology 
Affiliation  Rajarajeswari medical college and hospital  
Address  Rajarajeswari medical college and hospital kengeri satellite town kambipura Bangalore

Bangalore
KARNATAKA
560074
India 
Phone  9538220515  
Fax    
Email  drgskarthik@gmail.com  
 
Details of Contact Person
Public Query
 
Name  DrKarthik G S  
Designation  professor and HOD of department of Anaesthesiology 
Affiliation  Rajarajeswari medical college and hospital  
Address  Rajarajeswari medical college and hospital kengeri satellite town kambipura Bangalore


KARNATAKA
560074
India 
Phone  9538220515  
Fax    
Email  drgskarthik@gmail.com  
 
Source of Monetary or Material Support  
Department of anaesthesiology, 2nd floor , rajarajeswari medical college and hospital , bangalore-560074 
 
Primary Sponsor  
Name  Dr.Jasni K B  
Address  Rajarajeswari medical college and hospital, mysore road, kambipura, bangalore, karnataka-560074 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DrJasni K B  Rajarajeswari medical college and hospital  Department of Anaesthesiology, Rajarajeswari medical college and hospital , mysore road, kambipura, bangalore, karnataka - 560074
Bangalore
KARNATAKA 
9538808087

jasnibasheer97@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: S328||Fracture of other parts of pelvis,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Femoral nerve block with lateral cutaneous nerve block  With a linear probe, femoral nerve block will be performed at the inguinal crease level and lateral cutaneous nerve block inferior to anterior superior iliac spine. The probe will be placed below the inguinal ligament identifying the femoral vessels and nerves. Using 23G quincke babcock spinal needle, 20ml of the drug solution will be injected along the nerve sheath. Then the probe is positioned caudal to anterior superior iliac spine to visualise lateral femoral cutaneous nerve between sartorius muscle and tensor fascia lata and 5 ml of drug mixture is injected (5 mins) 
Comparator Agent  Pericapsular nerve block with lateral cutaneous nerve block   With a high frequency probe, which is placed in the transverse plane over the anterior inferior iliac spine moving inferiorly to visualise the pubic ramus using an in plane technique, the 23G quincke babcock spinal needle, 20 ml of drug volume will be deposited between the psoas tendon and superior pubic ramus. Lateral femoral cutaneous nerve block will be performed. (5 mins) 
 
Inclusion Criteria  
Age From  20.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  ASA 1 and 2 patients with valid informed consent undergoing elective hip fracture surgeries 
 
ExclusionCriteria 
Details  Patient refusal
Patients with coagulopathy
Patients with history of allergy to local anaesthetics
Patients with severe cardiopulmonary disease
Patients on chronic analgesic therapy
Patients with peripheral neuropathy 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Other 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
Duration of postoperative analgesia
 
Duration of postoperative analgesia
At 0 min, 5th min, 15th min, 30th min, 1st hour, 2nd hour, 6th hour, 10th hour, 14th hour, 18th hour, 24th hour 
 
Secondary Outcome  
Outcome  TimePoints 
Hemodynamic parameters
Total analgesia requirement
VAS score on passive leg raise
Any complications 
Both groups will be compared after the blocks given at 0 min, 5 min, 15 min, 30 min, 1 hour, 2 hours, 6 hours, 10 hours, 14 hours, 18 hours, 24 hours 
 
Target Sample Size   Total Sample Size="50"
Sample Size from India="50" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   01/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Geriatric patients undergoing hip surgery often experience severe pain after the surgery especially in the early post operative period which can lead to respiratory and cardiac complications, prolonged hospital stays and impaired mobility which ultimately results in poor postoperative outcomes.

The pericapsular nerve group (PENG) block is a novel block for hip surgery and pain management in hip fractures that is slowly gaining popularity. This technique blocks all three nerves that innervate the anterior aspect of the hip with a single injection. This block yields excellent pain control with an extremely low incidence of motor block. This approach is unable to manage the pain from the surgical incision since it spares the lateral femoral cutaneous nerve (LFCN).

The combination of PENG plus LFCN block is a relatively new approach with only a small number of case series and case reports available in the literature. Facia iliaca compartment block (FICB) may cause motor weakness, hindering early mobilization. PENG block, a novel technique, targets articular branches of key nerves, offering effective pain relief without significant motor impairment. The addition of lateral cutaneous nerve of thigh block to PENG block may further enhance analgesia.



 
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