| CTRI Number |
CTRI/2026/01/101841 [Registered on: 22/01/2026] Trial Registered Prospectively |
| Last Modified On: |
22/01/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
Effect of therapist guided joint movement versus patient performed movement exercises in people with osteoarthritis |
|
Scientific Title of Study
|
Effectiveness of Movement with Mobilization by Physiotherapist Versus Self Movement with Mobilization in Patients with Knee Osteoarthritis: RCT |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Pooja Ravindra Ashture |
| Designation |
Postgraduate student in Department of Musculoskeletal Physiotherapy |
| Affiliation |
Maharashtra Institute Of Physiotherapy |
| Address |
Department Of Musculoskeletal Physiotherapy, Maharashtra Institute Of Physiotherapy, Latur, MIMSR Campus, Ambajogai Road, Latur 413531
Latur
MAHARASHTRA
413531
India |
| Phone |
9022258667 |
| Fax |
02382-227246 |
| Email |
poojaashtur1999@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Subhash Khatri |
| Designation |
Principal and Professor at Maharashtra Institute Of Physiotherapy |
| Affiliation |
Maharashtra Institute Of Physiotherapy |
| Address |
Department Of Musculoskeletal Physiotherapy, Maharashtra Institute Of Physiotherapy, Latur, MIMSR Campus, Ambajogai Road, Latur 413531
Latur
MAHARASHTRA
413531
India |
| Phone |
8830174477 |
| Fax |
02382-227246 |
| Email |
physiokhatri@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Subhash Khatri |
| Designation |
Principal and Professor at Maharashtra Institute Of Physiotherapy |
| Affiliation |
Maharashtra Institute Of Physiotherapy |
| Address |
Department Of Musculoskeletal Physiotherapy, Maharashtra Institute Of Physiotherapy, Latur, MIMSR Campus, Ambajogai Road, Latur 413531
Latur
MAHARASHTRA
413531
India |
| Phone |
8830174477 |
| Fax |
02382-227246 |
| Email |
physiokhatri@gmail.com |
|
|
Source of Monetary or Material Support
|
| Department of Musculoskeletal Physiotherapy, Maharashtra Institute of Physiotherapy, Latur, MIMSR Campus, Ambajogai Road, 413531 |
|
|
Primary Sponsor
|
| Name |
Maharashtra Institute of Physiotherapy, Latur |
| Address |
Maharashtra Institute of Physiotherapy, MIMSR Campus, Ambajogai Road, Latur 413531 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
| Name |
Address |
| Short Term Research Grant Maharashtra University of Health Sciences Nashik |
Maharashtra University of Health Sciences, Nashik, Dindori Road, Mhasrul, Nashik 422004 |
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Pooja Ravindra Ashture |
Maharashtra Institute of Physiotherapy, Latur |
Department of Musculoskeletal Physiotherapy, OPD 15, Maharashtra Institute of Physiotherapy, Latur, MIMSR campus, Ambajogai road, Latur 413531
Latur
MAHARASHTRA |
9022258667
poojaashtur1999@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M170||Bilateral primary osteoarthritis of knee, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Movement with Mobilization by Physiotherapist |
Interventional group participants will receive Movement with Mobilization by Physiotherapist of knee joint lateral and medial glide along with progressive strengthning exercises 5 sessions per week for 2 weeks each session lasting for 30 min. |
| Comparator Agent |
Self Movement with Mobilization |
Comparative group participants will receive self Movement with Mobilization under observation of knee joint lateral and medial glide along with progressive strengthning exercises 5 sessions per week for 2 weeks each session lasting for 30 min. |
|
|
Inclusion Criteria
|
| Age From |
40.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
1. Clinically and radiographically confirmed knee osteoarthritis base on Kellgren-Lawrence Grade 2 and 3
2. Knee pain for more than 3 months.
3. Limited knee joint range of motion compared to contralateral side or normal range of motion.
4. Participants willing to provide written informed consent and commit to the study protocol.
5. Participants who are not engaged in pervious physiotherapy treatment. |
|
| ExclusionCriteria |
| Details |
1.Recent trauma or injury to the knee in the last 6 months.
2.Previous knee joint replacement surgery or significant knee surgeries.
3.Neurological Conditions such as stroke, peripheral neuropathies
4.Rheumatoid arthritis, gout, or other inflammatory joint diseases.
5.Uncontrolled hypertension, diabetes, or cardiovascular diseases.
6.Osteoporosis and severe joint instability. |
|
|
Method of Generating Random Sequence
|
Random Number Table |
|
Method of Concealment
|
Alternation |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
1.Visual analogue scale (VAS)
2.Range of motion (ROM) by Goniometer
3.Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)scale |
All outcomes will be assessed at the baseline and post intervention that is after 2 weeks. |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="50"
Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
02/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This is a Randomized clinical trial Subjects will be included according to inclusion and exclusion criteria. The entire procedure involved in this study will be explained to each subject. A written informed consent will be obtained from the participants. Demographic data of the participants will be collected. Patients will be assessed for visual analogue scale (VAS), Range of Motion (ROM), WOMAC scale pre and post to the intervention. Group A that is intervention group will receive movement with mobilization by the physiotherapist for knee joint medial and lateral glide along with progressive resisted exercises for 5 days per week for 2 weeks each lasting for 30 min. Group B that is comparative group will receive self movement with mobilization under observation for knee joint medial and lateral glide along with progressive resisted exercises for 5 days per week for 2 weeks each lasting for 30 min. |