| CTRI Number |
CTRI/2026/03/105966 [Registered on: 11/03/2026] Trial Registered Prospectively |
| Last Modified On: |
11/03/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group, Active Controlled Trial |
|
Public Title of Study
|
Which Works Better for Upper Trapezius Trigger Points when applied MFR & IC or Cryostretching & MET |
|
Scientific Title of Study
|
Comparative Study on the Effectiveness of Myofascial Release and Ischemic Compression vs Cryostretching and Muscle Energy Technique in the Management of Upper Trapezius Trigger Points |
| Trial Acronym |
CUTT Trial |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Sejal jain |
| Designation |
Student |
| Affiliation |
Amity university, nodia |
| Address |
Amity Institute of Health Allied Sciences (AIHAS) F 1 Block, LGF, Sector-125, Noida-201303, India. Sector-125, Amity University NOIDA (UP)-201301, INDIA
Amity university, nodia
Gautam Buddha Nagar
UTTAR PRADESH
201301
India |
| Phone |
9412221602 |
| Fax |
|
| Email |
sejaljain2102@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Bhumika Chibber |
| Designation |
Professor |
| Affiliation |
Amity university, noida |
| Address |
Amity Institute of Health Allied Sciences (AIHAS) F 1 Block, LGF, Sector 125, Noida-201303, India. Sector 125, Amity University NOIDA (UP)201301, INDIA
Amity Institute of Health Allied Sciences (AIHAS) F 1 Block, LGF, Sector 125, Noida-201303, India. Sector 125, Amity University NOIDA (UP) 201301, INDIA
Gautam Buddha Nagar
UTTAR PRADESH
201301
India |
| Phone |
9899223561 |
| Fax |
|
| Email |
bchhibber@amity.edu |
|
Details of Contact Person
Public Query
|
| Name |
Dr Bhumika Chibber |
| Designation |
Professor |
| Affiliation |
Amity university, noida |
| Address |
Amity Institute of Health Allied Sciences (AIHAS) F 1 Block, LGF, Sector 125, Noida-201303, India. Sector 125, Amity University NOIDA (UP)201301, INDIA
Amity Institute of Health Allied Sciences (AIHAS) F 1 Block, LGF, Sector 125, Noida-201303, India. Sector 125, Amity University NOIDA (UP) 201301, INDIA
Gautam Buddha Nagar
UTTAR PRADESH
201301
India |
| Phone |
9899223561 |
| Fax |
|
| Email |
bchhibber@amity.edu |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Self funded |
| Address |
Amity university, hapur |
| Type of Sponsor |
Other [Educational university ] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Ritika Aggarwal |
Amity university |
Amity university sec 125 noida uttar pradesh F2 block room no 101
Gautam Buddha Nagar
UTTAR PRADESH |
8126120201
ritikaag22@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Amity university of health and allied science |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M638||Disorders of muscle in diseases classified elsewhere, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Myofascial Release and Ischemic Compression + Cryostretching and Muscle Energy Technique |
Myofascial Release applied to the upper trapezius using sustained manual pressure and longitudinal gliding for 5–7 minutes followed by Ischemic Compression applied over the active trigger point with gradually increasing pressure for 60–90 seconds. Total session duration 10–12 minutes, administered 3 sessions per week for 2 weeks. Cryostretching applied using ice massage for 3–5 minutes followed by static stretching of the upper trapezius for 30 seconds × 3 repetitions. Muscle Energy Technique applied using post-isometric relaxation with the patient performing gentle isometric contraction for 5–7 seconds followed by passive stretch. Total session duration 10–12 minutes, administered 3 sessions per week for 2 weeks. |
| Comparator Agent |
not applicable |
not applicable |
|
|
Inclusion Criteria
|
| Age From |
25.00 Year(s) |
| Age To |
35.00 Year(s) |
| Gender |
Both |
| Details |
Presence of any neurological disorders
• History of shoulder or neck surgery
• Diagnosed with severe psychiatric illnesses bone related
diseases tumors or infections
• Diagnosed with cervical radiculopathy, myelopathy, or disc
herniation
• Local skin infections, open wounds, or recent injections in the
treatment area
• Currently undergoing other physiotherapy treatments for neck or
shoulder
• Pregnancy |
|
| ExclusionCriteria |
| Details |
Presence of any neurological disorders
•History of shoulder or neck surgery
•Diagnosed with severe psychiatric illnesses bone related diseases tumors or infections
•Diagnosed with cervical radiculopathy, myelopathy, or disc herniation
•Local skin infections, open wounds, or recent injections in the treatment area
•Currently undergoing other physiotherapy treatments for neck or shoulder
•Pregnancy
•Previous traumatic injuries involving the upper limb or cervical spine (e.g., fractures or dislocations)
•Other systemic conditions such as thyroid issues, cardiac, pulmonary diseases, etc.
|
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Outcome Assessor Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Reduction in pain intensity measured using VAS scale |
Reduction in pain intensity measured using VAS scale |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Improvement in cervical lateral flexion range of motion measured using a universal goniometer |
Baseline (Day 0) and End of Week 2 |
|
|
Target Sample Size
|
Total Sample Size="100"
Sample Size from India="100"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
26/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="1"
Days="15" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study aims to compare the effectiveness of Myofascial Release combined with Ischemic Compression versus Cryostretching combined with Muscle Energy Technique in the management of upper trapezius myofascial trigger points. Upper trapezius trigger points commonly cause neck pain restricted movement and muscle tenderness. Thirty participants aged eighteen to forty years with clinically diagnosed active trigger points in the upper trapezius will be randomly allocated into two groups. Group A will receive Myofascial Release followed by Ischemic Compression and Group B will receive Cryostretching followed by Muscle Energy Technique. The intervention will be provided three sessions per week for two weeks. Pain intensity cervical range of motion and pressure pain threshold will be assessed at baseline week one and week two. The primary objective is to determine which treatment approach produces greater reduction in pain and muscle tenderness. The study may help clinicians choose a more effective manual therapy and stretching protocol for treating upper trapezius trigger points.
|