| CTRI Number |
CTRI/2025/12/098931 [Registered on: 11/12/2025] Trial Registered Prospectively |
| Last Modified On: |
11/12/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Cross Sectional Study |
| Study Design |
Other |
|
Public Title of Study
|
Predicting the Seriousness of Acute Pancreatitis Using a Routine Blood Test . |
|
Scientific Title of Study
|
Evaluation of neutrophil to lymphocyte ratio as a predictive marker for severity of acute pancreatitis |
| Trial Acronym |
nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Manish chandey |
| Designation |
Professor |
| Affiliation |
Sri Guru Ram das University of medical health sciences, vallah |
| Address |
260 A , medical enclave circular road , Amritsar, punjab , India .
Amritsar
PUNJAB
143001
India |
| Phone |
9872071231 |
| Fax |
|
| Email |
chandey96098@yahoo.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Manish chandey |
| Designation |
Professor |
| Affiliation |
Sri Guru Ram das University of medical health sciences, vallah |
| Address |
260 A , medical enclave circular road , Amritsar , punjab , India
Amritsar
PUNJAB
143001
India |
| Phone |
9872071231 |
| Fax |
|
| Email |
chandey96098@yahoo.com |
|
Details of Contact Person
Public Query
|
| Name |
Sahibdeep kaur athwal |
| Designation |
Junior resident |
| Affiliation |
Sri Guru Ram das University of medical health sciences, vallah |
| Address |
303/4 quadian road , ujjagar nagar batala, punjab , india
Gurdaspur
PUNJAB
143505
India |
| Phone |
6230870071 |
| Fax |
|
| Email |
sahibdeep2424@gmail.com |
|
|
Source of Monetary or Material Support
|
| Department of medicine , Shri guru Ram das University of health sciences |
|
|
Primary Sponsor
|
| Name |
department of medicine |
| Address |
Shri guru Ram das University of health sciences |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Manish chandey |
Shri guru Ram das University of health sciences |
Department of medicine
Amritsar
PUNJAB |
9872071231
chandey96098@yahoo.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional ethics committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: K859||Acute pancreatitis, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
99.00 Year(s) |
| Gender |
Both |
| Details |
Age 18 or above .
Patient diagnosed with acute pancreatitis. |
|
| ExclusionCriteria |
| Details |
Patient with haematological disorder.
Patient with active infection.
Patient on prior antibiotics.
Patient on prior steroids .
Patient on prior chemotherapy.
Recent major surgery.
PREGNANT FEMALE |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Higher neutrophil to lymphocyte ratio is significantly associated with increased severity of acute pancreatitis. |
Baseline |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| nil |
nil |
|
|
Target Sample Size
|
Total Sample Size="80"
Sample Size from India="80"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
23/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study aims to assess whether the neutrophil-to-lymphocyte ratio (NLR), a simple blood test parameter, can be used as an reliable marker to predict the severity of acute pancreatitis. By analyzing NLR levels in patients with acute pancreatitis and comparing them with disease severity, the study evaluates its usefulness in early risk stratification. The findings may help in better treatment planning, and improved patient outcomes using a cost-effective and easily available marker . |