| CTRI Number |
CTRI/2025/11/098192 [Registered on: 28/11/2025] Trial Registered Prospectively |
| Last Modified On: |
28/11/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Homeopathy |
| Study Design |
Randomized, Parallel Group, Placebo Controlled Trial |
|
Public Title of Study
|
To Evaluate The Efficacy Of Individualized Homoeopathic Treatment In Patients Suffering From Rheumatoid Arthritis. |
|
Scientific Title of Study
|
A Randomized Controlled Trial To Evaluate The Efficacy Of Individualized Homoeopathic Treatment In Patients Suffering From Rheumatoid Arthritis. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
LAKSHAY MAHAJAN |
| Designation |
PG SCHOLAR |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute ,Rajasthan,335002,India Department - Materia Medica
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9465301669 |
| Fax |
|
| Email |
lakshaymahajan25@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
DR CHARANJEET SINGH |
| Designation |
B.Sc. , B.H.M.S , MD (Hom) , Ph.D ( Hom) |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute, Rajasthan 335002,India
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9414225433 |
| Fax |
|
| Email |
sgnhh@yahoo.com |
|
Details of Contact Person
Public Query
|
| Name |
LAKSHAY MAHAJAN |
| Designation |
PG SCHOLAR |
| Affiliation |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
| Address |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute, Rajasthan 335002,India
Ganganagar
RAJASTHAN
335002
India |
| Phone |
9465301669 |
| Fax |
|
| Email |
lakshaymahajan25@gmail.com |
|
|
Source of Monetary or Material Support
|
| TANTIA UNIVERSITY - Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute , Rajasthan 335002 |
|
|
Primary Sponsor
|
| Name |
TANTIA UNIVERSITY |
| Address |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute, Rajasthan 335002 Department- Materia Medica |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| DR LAKSHAY MAHAJAN |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute |
Sri Ganganagar Homoeopathic Medical College Hospital and Research Institute
Ganganagar
RAJASTHAN |
9465301669
lakshaymahajan25@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M059||Rheumatoid arthritis with rheumatoid factor, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Comparing patients taking Homoeopathic medicines and placebo in cases of Rheumatoid Arthritis |
Giving placebo to some patients by process of randomization by various ways like flip coin, toss etc. Mode of administration - oral. Duration - 1 year |
| Intervention |
To give Individualized homoeopathic medicines to patients suffering from Rheumatoid Arthritis |
To give individualized homoeopathic medicines to patients suffering from Rheumatoid Arthritis on the basis of similimum . Potency - 30ch, 200ch, 1M. Mode of administration -oral . Duration - 1 year |
|
|
Inclusion Criteria
|
| Age From |
25.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
1. Patients aged 25-60 years with clinically diagnosed and undiagnosed Rheumatoid Arthritis
2 . Gender both Male and Female
3. Both serological positive and negative cases |
|
| ExclusionCriteria |
| Details |
1. Patients coming with severe comorbidities like CKD , LIVEER DISEASES , HEART DISEASES etc.
2 . Pregnant or Lactating individuals |
|
|
Method of Generating Random Sequence
|
Coin toss, Lottery, toss of dice, shuffling cards etc |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Improvement in Rheumatoid Arthritis symptoms in patients treated with homoeopathic medicines compared to placebo |
Follow ups every 15 days for 6 months |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Symptomatic amelioration in patients suffering from Rheumatoid Arthritis by counselling and lifestyle management |
Follow ups every 15 days for six months |
|
|
Target Sample Size
|
Total Sample Size="100"
Sample Size from India="100"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
09/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Rheumatoid Arthritis (RA) is a chronic, autoimmune, and debilitating disease characterized by inflammation, pain, swelling, and eventual destruction of joints. It affects millions of people worldwide, leading to significant morbidity, disability, and decreased quality of life. RA is a complex disorder involving an interplay between genetic, environmental, and immune system factors. The disease process involves the activation of immune cells, release of pro-inflammatory cytokines, and production of autoantibodies, which ultimately lead to joint damage and destruction. The current conventional treatment options for RA include non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs), and biologic agents. However, these treatments have limitations, including side effects, toxicity, and high costs. Moreover, some patients may not respond adequately to these treatments, highlighting the need for alternative therapeutic approaches. In this context, Homoeopathy, a system of alternative medicine, offers a promising approach to managing RA. Homoeopathic remedies, derived from natural sources, aim to stimulate the body’s self-healing mechanisms and restore balance. Several Homoeopathic remedies have shown potential in reducing inflammation, pain, and improving quality of life in patients with RA. This study aims to investigate the efficacy of Homoeopathic treatment in managing Rheumatoid Arthritis. |