| CTRI Number |
CTRI/2025/11/097450 [Registered on: 14/11/2025] Trial Registered Prospectively |
| Last Modified On: |
14/11/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA)
Other (Specify) [Virtual reality ] |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
Virtual Reality Training to Reduce Motion Sickness |
|
Scientific Title of Study
|
Effect Of Virtual Reality And Vestibular Adaptation Exercises In Motion Sickness - An Experimental Study |
| Trial Acronym |
Nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Sahana A |
| Designation |
Associate Professor |
| Affiliation |
Chitkara University, Rajpura, Punjab. |
| Address |
Department of Physiotherapy, Chitkara University, Rajpura, Punjab.
Patiala
PUNJAB
140401
India |
| Phone |
8264212162 |
| Fax |
|
| Email |
sahana.a@chitkara.edu.in |
|
Details of Contact Person
Scientific Query
|
| Name |
Birinder Kaur |
| Designation |
Research Assistant |
| Affiliation |
Chitkara University, Rajpura, Punjab. |
| Address |
Department of Physiotherapy, Chitkara University, Rajpura, Punjab.
Patiala
PUNJAB
140401
India |
| Phone |
9517217509 |
| Fax |
|
| Email |
birinder.kaur@chitkara.edu.in |
|
Details of Contact Person
Public Query
|
| Name |
Birinder Kaur |
| Designation |
Research Assistant |
| Affiliation |
Chitkara University, Rajpura, Punjab. |
| Address |
Department of Physiotherapy, Chitkara University, Rajpura, Punjab.
Patiala
PUNJAB
140401
India |
| Phone |
9517217509 |
| Fax |
|
| Email |
birinder.kaur@chitkara.edu.in |
|
|
Source of Monetary or Material Support
|
| Chitkara University OPD, Department of Physiotherapy. |
|
|
Primary Sponsor
|
| Name |
Nil |
| Address |
Nil |
| Type of Sponsor |
Other [Nil] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Birinder Kaur |
Chitkara University |
Department of Physiotherapy, Chitkara University, Rajpura (140401)
Patiala
PUNJAB |
9517217509
birinder.kaur@chitkara.edu.in |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| INSTITUTIONAL HUMAN ETHICAL COMMITTEE CHITKARA UNIVERSITY, PUNJAB |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: T753||Motion sickness, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Vestibular adaptation exercises |
• Each patient will perform Vestibular Adaptation exercises 3 times per week for 4 weeks, with each session lasting 40 minutes.
• Exercises will be carried out in the following sequence:
Rising While Focused
Sitting in a chair, focus on a stable object across the room, 5 to 10 feet away. Keeping your focus on this object, stand up. Repeat this exercise as prescribed and remain balanced. Then practice sitting and standing with your eyes closed.
INTENSITY: 5 repetitions / 30 seconds. Total= 20 repetitions.
2 minutes break after every 5 repetitions. DURATION: 10 min
Moving Head While Focused
Focus your gaze on a bright object about 5-feet away. This could be a picture on the wall or a target printed on a piece of paper and tacked to the wall. Keep your eyes focused on this object while you turn your head from side to side, slowly at first, then more rapidly.
INTENSITY: 5 repetitions / 30 seconds. Total= 20 repetitions.
2 minutes break after every 5 repetitions. DURATION: 10 min.
Focus on Moving Target
This time, you remain still but follow the movement of a target with your eyes. The direction of the target’s movement will vary, from side to side to up and down and diagonal.
INTENSITY: 5 repetitions / 30 seconds. Total= 20 repetitions.
2 minutes break after every 5 repetitions. DURATION: 10 min..
Move with Moving Target
While focused on a target, you’ll be asked to move your head in the opposite direction of the target, while keeping your eyes locked to the target. You may also be asked to move in the same direction as the target.
INTENSITY: 5 repetitions / 30 seconds. Total= 20 repetitions.
2 minutes break after every 5 repetitions. DURATION: 10 min.
|
| Intervention |
Virtual reality |
• Each patient will undergo VR-based therapy 3 times per week for 4 weeks, with each session lasting 9 minutes.
• The VR content will be played on a mobile phone inserted into a VR headset.
• The sequence of videos shown in each session will be:
1. Straight line pathway
2. Curvy path
3. Ship with waves
4. Storm simulation
5. Roller coaster ride
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
40.00 Year(s) |
| Gender |
Both |
| Details |
1) Individuals aged between 18-40 years
2) Individuals experiencing motion sickness.
|
|
| ExclusionCriteria |
| Details |
1) Pre-existing vestibular disorders, neurological conditions.
2) Contraindications to VR use, such as individuals with epilepsy, visual impairments, cardiovascular conditions, anxiety.
3) Participants having ear infection or surgery.
|
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
On-site computer system |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
Modified Motion Sensitivity Test (MMS Test).
|
Baseline and 4 weeks
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Nil |
Nil |
|
|
Target Sample Size
|
Total Sample Size="56"
Sample Size from India="56"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
06/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This experimental study explores how virtual reality exposure combined with vestibular adaptation exercises can reduce motion sickness. Participants undergo controlled VR sessions and targeted vestibular training aimed at improving sensory integration and tolerance to motion-related stimuli. The study evaluates changes in symptoms, balance responses, and adaptation over time. Findings may support using VR-based rehabilitation and vestibular exercises as effective, non-invasive strategies for managing motion sickness in clinical and functional settings. |