| CTRI Number |
CTRI/2025/12/098964 [Registered on: 11/12/2025] Trial Registered Prospectively |
| Last Modified On: |
11/12/2025 |
| Post Graduate Thesis |
No |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Other |
|
Public Title of Study
|
Effectiveness of Magneto-mechanical Vibrations on range of motion, Pain and functional mobility among subjects with knee osteoarthritis. |
|
Scientific Title of Study
|
Effectiveness of magneto-mechanical vibrations on range of motion, pain and functional mobility among subjects with knee osteoarthritis. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Sweshadev Nayak |
| Designation |
Associate Professor |
| Affiliation |
R.V.S. College of Physiotherapy, Sulur |
| Address |
R.V.S.College of Physiotherapy,
Room No, 111, Department of Orthopaedics Sulur, Coimbatore.
Coimbatore
TAMIL NADU
641402
India |
| Phone |
9047820365 |
| Fax |
|
| Email |
sdevmpt@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Sweshadev Nayak |
| Designation |
Associate Professor |
| Affiliation |
R.V.S. College of Physiotherapy, Sulur |
| Address |
R.V.S.College of Physiotherapy,
Room No. 111, Department of Orthopaedics, Sulur, Coimbatore.
Coimbatore
TAMIL NADU
641402
India |
| Phone |
9047820365 |
| Fax |
|
| Email |
sdevmpt@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Sweshadev Nayak |
| Designation |
Associate Professor |
| Affiliation |
R.V.S. College of Physiotherapy, Sulur |
| Address |
R.V.S.College of Physiotherapy,
Room No. 111, Department of Orthopaedics ,Sulur, Coimbatore.
Coimbatore
TAMIL NADU
641402
India |
| Phone |
9047820365 |
| Fax |
|
| Email |
sdevmpt@gmail.com |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Sweshadev Nayak. |
| Address |
242 Trichy road, Sulur, Coimbatore-641402 |
| Type of Sponsor |
Research institution |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 2 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr MK Franklin Shaju |
K.M.C.H Hospital |
242 Trichy Road, Sulur, Coimbatore -641402.
Coimbatore
TAMIL NADU |
0422-2687421
sdevmpt@gmail.com |
| Sweshadev Nayak |
Physiotherapy out-patient department |
RVS College of Physiotherapy, Room No. 111, Department of Orthopaedics, Sulur, Coimbatore-641402.
Coimbatore
TAMIL NADU |
9047820365
sdevmpt@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| INSTITUTIONAL HUMAN ETHICS COMMITTEE RVS College of Physiotherapy |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: M179||Osteoarthritis of knee, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
CONVENTIONAL GROUP |
Moist heat and exercises. Exercises will include 1.Hamstring stretching 2.Quadriceps strengthening exercises. stretching will be given for 6 repetitions and strengthening will be given for 30 repetitions per session, both will be continued for 5 sessions per week for 2 weeks. Moist heat therapy will be given for 10 minutes. |
| Intervention |
EXPERIMENTAL GROUP |
Experimental group will receive magneto-mechanical vibrations along with Moist heat and exercises. Magneto-mechanical vibrations will be given for 60 minutes. Exercises will include 1.Hamstring stretching 2.Quadriceps strengthening exercises.
stretching will be given for 6 repetitions and strengthening will be given for 30 repetitions per session, both will be continued for 5 sessions per week for 2 weeks. Moist heat therapy will be given for 10 minutes. |
|
|
Inclusion Criteria
|
| Age From |
50.00 Year(s) |
| Age To |
70.00 Year(s) |
| Gender |
Both |
| Details |
1. Subjects clinically diagnosed to have Knee Osteoarthritis and willing to participate in
the study.
2. Age group of 50 to 70 years.
3. Both male and Female subjects will be included in the study. |
|
| ExclusionCriteria |
| Details |
1. Recent injury to the Knee.
2. Local Surgery
3. Skin lesions, inflamed or infected skin
4. Recent fractures
5. Heightened tendency toward bleeding/ clotting
6. Heightened risk of embolism
7. Heart pacemaker
8. Obesity
9. Metabolic disorders |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
It is anticipated that all the participants who will undergo magneto-mechanical
vibrations (Matrixmobil) along with conventional physiotherapy and conventional
physiotherapy alone will experience reduction in pain, improvement in knee ROM,
reduction in postural sway, and improvement in functional mobility. |
Pre-test measurement at zero week
Post-test measurement I (after 3 weeks)Post-test measurement II (after 6 weeks) |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="144"
Sample Size from India="144"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
23/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study aims to
evaluate how magneto-mechanical vibrations Matrix
rhythm therapy can
help people with knee osteoarthritis by
improving pain, knee range of motion , postural
stability, and functional mobility. Knee osteoarthritis is a
common degenerative condition that causes pain and limits daily activities, and
current physiotherapy treatments do not fully stop its progression.
Matrix
rhythm therapy uses gentle vibrations 8–12 Hz combined with magnetic
oscillations to stimulate muscle cells, improve tissue mobility and reduce
stiffness. The study compares two groups:
Group A: Matrix rhythm therapy and conventional physiotherapy
Group B: Conventional physiotherapy alone
A
total of 144 participants will be
assessed over 6 weeks, using tools such as the
Visual Analogue Scale for pain, goniometer for ROM, stabilometric platform for
postural sway, and the Timed Up and Go test for mobility.
The
study expects that both groups will improve, but Matrix rhythm therapy combined with
physiotherapy will provide greater
relief in pain, better knee movement, reduced postural sway and improved
mobility compared to physiotherapy alone.
The
results may introduce a new, effective physiotherapy method to enhance
functional mobility in knee osteoarthritis patients.
|