| CTRI Number |
CTRI/2025/12/098331 [Registered on: 02/12/2025] Trial Registered Prospectively |
| Last Modified On: |
01/12/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Homeopathy |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Use of Murphy Repertory in cases of Gastro Oesophageal Reflux Disease of age group 30 to 60 years |
|
Scientific Title of Study
|
Application of prescribed Homeopathic medicine from rubrics of Murphy Repertory in management of GERD among 30 to 60 years of age group assessed by GERD-Q-An experimental study |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Tanvi Thakkar |
| Designation |
PG Scholar |
| Affiliation |
Smt A J Savla Homoeopathic medical college and research institute |
| Address |
Room number 06 Department of medicine ground floor Smt AJ Savla Homoeopathic medical college and research institute pushpanjali building near district session court Mahesana Gujarat
Mahesana
GUJARAT
384001
India |
| Phone |
7434064673 |
| Fax |
|
| Email |
tanvithakkar731@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Neha Patel |
| Designation |
Professor PG Department of Repertory |
| Affiliation |
Smt A J Savla Homoeopathic medical college and research institute |
| Address |
Smt A J Savla Homoeopathic medical college and research institute pushpanjali building near district session court Mahesana Gujarat
Mahesana
GUJARAT
384001
India |
| Phone |
9428458613 |
| Fax |
|
| Email |
drnehpatel13@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Tanvi Thakkar |
| Designation |
PG Scholar |
| Affiliation |
Smt A J Savla Homoeopathic medical college and research institute |
| Address |
Room number 06 Department of medicine ground floor Smt A J Savla Homoeopathic medical college and research institute pushpanjali building near district session court Mahesana Gujarat
Mahesana
GUJARAT
384001
India |
| Phone |
7434064673 |
| Fax |
|
| Email |
tanvithakkar731@gmail.com |
|
|
Source of Monetary or Material Support
|
| Smt A J Savla Homoeopathic medical college and research institute pushpanjali building near district session court Mahesana Gujarat
|
|
|
Primary Sponsor
|
| Name |
Dr Tanvi Thakkar |
| Address |
Room number 06 Department of medicine ground floor Smt A J Savla Homoeopathic medical college and research institute pushpanjali building near district session court Mahesana Gujarat
|
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Tanvi Thakkar |
Smt A J Savla Homeopathic medical college and research institue |
Room number 06 Department of medicine ground floor pushpanjali building near district session court Mahesana Gujarat
Mahesana
GUJARAT |
7434064673
tanvithakkar731@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Smt A J Savla homeopathic medical college institutional ethical committe |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: K219||Gastro-esophageal reflux disease without esophagitis, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Individualised Homoeopathic Medicine |
Medicine will be dispense in doses as per the need of case and in different potencies such as decimal scale centesimal scale 50millesimal scale etc
Route of administration is oral route
Duration of therapy is upto 10 months as per need of case |
| Comparator Agent |
NIL |
NIL |
|
|
Inclusion Criteria
|
| Age From |
30.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
1 Already diagnosed cases of GERD according to ICD-11 (DA22.Z)
2 Patients with age group 30 to 60 years, both sexes, all religion and socioeconomic status.
3 Consent: patient who are willing to provide a written informed consent to participate in the study.
|
|
| ExclusionCriteria |
| Details |
1 Severe gastro enterology complications like Barrett’s oesophagus oesophageal stricture.
2 Patient having alarming symptoms such as gastro intestinal haemorrhage or any systemic disease such as cardiac pulmonary hepatic or renal diseases.
3 Patient who have received any form of treatment (Homeopathic ayurvedic allopathic or any other alternative therapies) for GERD with in past 10 days.
4 Patient having severe psychiatric disorder like depression with suicidal tendency schizophrenia bipolar disorder cognitive disorder like dementia.
5 Abdominal surgery within past 6 months
|
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Change in the Gastro-Oesophageal reflux disease Questionarrie score |
score will be assessed at baseline and at the end of study |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
12/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
This study is prospective pre-test post-test single group true experimental study to assess the clinical utility of Murphy repertory in managing the cases of Gastro-oesophageal reflux disease with GERD-Q for 10 months in 30 participants with GERD selected according to inclusion and exclusion criteria from out patient department and the outcomes will assess in reducing the symptoms with GERD-Q at baseline and at the end of the treatment |