| CTRI Number |
CTRI/2026/02/102676 [Registered on: 02/02/2026] Trial Registered Prospectively |
| Last Modified On: |
02/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Cohort Study |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Role of homoeopathic medicine in managing migraine disability. |
|
Scientific Title of Study
|
Effectiveness of individualized homoeopathic medicines with miasmatic analysis in managing migraine disability and enhancing quality of life. |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Manisha Gupta |
| Designation |
Postgraduate trainee |
| Affiliation |
State national homoeopathic medical college and hospital lucknow |
| Address |
Department of Organon of medicine ,State National Homoeopathic Medical College and Hospital 1-Viraj khand Gomti Nagar Lucknow
Lucknow
UTTAR PRADESH
226010
India |
| Phone |
8604536453 |
| Fax |
|
| Email |
drmanishagupta24@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Ruchi Wadhwa |
| Designation |
Professor |
| Affiliation |
State national homoeopathic medical college and hospital lucknow |
| Address |
Department of Forensic medicine and toxicology, State National Homoeopathic Medical College and Hospital 1-Viraj khand Gomti Nagar Lucknow
Lucknow
UTTAR PRADESH
226010
India |
| Phone |
9667674366 |
| Fax |
|
| Email |
ruchibiswas.rb@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Manisha Gupta |
| Designation |
Postgraduate trainee |
| Affiliation |
State national homoeopathic medical college and hospital lucknow |
| Address |
Department of Organon of medicine ,State National Homoeopathic Medical College and Hospital 1-Viraj khand Gomti Nagar Lucknow
Lucknow
UTTAR PRADESH
226010
India |
| Phone |
8604536453 |
| Fax |
|
| Email |
drmanishagupta24@gmail.com |
|
|
Source of Monetary or Material Support
|
| Out patient department of State National Homoeopathic Medical College and Hospital 1-viraj khand Gomti Nagar Lucknow UTTAR PRADESH 226010 |
|
|
Primary Sponsor
|
| Name |
Manisha Gupta |
| Address |
Department of Organon of medicine and homoeopathic philosophy, State National Homoeopathic Medical College and Hospital 1-viraj khand Gomti Nagar Lucknow Uttar Pradesh -226010 |
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Manisha Gupta |
State National Homoeopathic Medical College and Hospital Lucknow |
OPD-5, Department of Organon of medicine and homoeopathic philosophy, State National Homoeopathic Medical College and Hospital 1-Viraj khand Gomti Nagar
Lucknow
UTTAR PRADESH |
8604536453
drmanishagupta24@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee of State National Homoeopathic Medical College and Hospital Lucknow |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: G439||Migraine, unspecified, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
NIL |
Being an observational study we will watch the effect of individualized homoeopathic medicine on the patient after it is given and observe the health of patient. |
|
|
Inclusion Criteria
|
| Age From |
25.00 Year(s) |
| Age To |
60.00 Year(s) |
| Gender |
Both |
| Details |
1.Patient who are willing for inclusion in study and giving consent to participate.
2.Those who are able to come for further follow-up.
3.Clinically diagnosed cases of migraine.
4.Sample include patient of age 25 to 60 years and both sex. |
|
| ExclusionCriteria |
| Details |
1. Patient unwilling for inclusion in the study and those who are not able to come for follow-ups.
2. Patient suffering from psychiatric disease and other illness.
3.Pregnant women and nursing mothers.
4.Any brain pathology detected on CT Scan of brain. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Open Label |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To evaluate the effect of individualized homoeopathic medicine selected with miasmatic analysis and repertorization on the basis of MIDAS score before and after treatment. |
30 Days |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| To evaluate the effect of individualized homoeopathic medicine selected with miasmatic analysis and repertorization on the basis of Migraine specific quality of life questionnaire and MIDAS score before and after treatment. |
3 Months |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
16/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Migraine is a debilitating neurological condition characterized by recurring episodes of
moderate-to-severe headaches, which are accompanied by nausea, sensitivity to light , and sensitivity to sound. A recurrent headache disorder with
attacks lasting 4–72hours if untreated featuring unilateral, throbbing pain of moderate-tosevere intensity worsened by activity, alongside nausea or sensitivity to light and
sound. At the end of study, it is expected that the individualized homoeopathic medicine selected using miasmatic analysis and synthesis repertory have effective role in the management of patients who are suffering with Migraine. It is expected that the patient improves symptomatically which is evident through the valid scales like MIDAS score and Migraine specific quality of life questionnaire. |