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CTRI Number  CTRI/2025/12/098425 [Registered on: 03/12/2025] Trial Registered Prospectively
Last Modified On: 03/12/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Dentistry 
Study Design  Other 
Public Title of Study   Comparison of two surgical techniques in the treatment of receding gums  
Scientific Title of Study   Vestibular incision subperiosteal tunnel access (VISTA) technique with collagen membrane compared to VISTA alone for treatment of multiple gingival recession defects: In vivo study 
Trial Acronym  nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Rakshitha S 
Designation  Post graduate  
Affiliation  JSS Dental college and Hospital 
Address  Department of Periodontology Room number 9 JSS Dental College and Hospital Bangalore Mysore highway Bannimantap Mysore 570015

Mysore
KARNATAKA
570015
India 
Phone  09880355071  
Fax    
Email  rakshitha074@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Pratibha Shashikumar  
Designation  Reader  
Affiliation  JSS Dental college and Hospital 
Address  Department of Periodontology Room number 9 JSS Dental college and Hospital Banglore Mysore highway Bannimantap Mysore 570017

Mysore
KARNATAKA
570015
India 
Phone  9986544409  
Fax    
Email  drpratibhavg@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr.Shivananda S 
Designation  Reader 
Affiliation  JSS Dental college and Hospital 
Address  Department of Oral and Maxillofacial Surgery Room number 6 JSS Dental college and Hospital Bangalore Mysore highway Bannimantap Mysore
dr.shivanandas@jssuni.edu.in
Mysore
KARNATAKA
570015
India 
Phone  9343322433  
Fax    
Email  rakshitha074@gmail.com  
 
Source of Monetary or Material Support  
JSS Dental college and Hospital Banglore Mysore highway Bannimantap Mysore India 570015  
 
Primary Sponsor  
Name  JSS Dental college and Hospital 
Address  JSS Dental College and Hospital Bangalore Mysore highway Bannimantap Mysore India 570015 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Rakshitha S  JSS Dental Colleg and Hopsital departement of Peridontology   Department of Periodontology Room number 9 JSS Dental college and Hospital Banglore Mysore highway Bannimantap Mysore
Mysore
KARNATAKA 
09880355071

rakshitha074@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
JSS Dental college and Hospital Institutional Ethics Committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Oral conditions like Periodontitis 
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Vestibular incision subperiosteal tunnel access (VISTA) technique with collagen membrane compared to VISTA alone for treatment of multiple gingival recession defects: In Vivo Study  Control group VISTA alone  
Intervention  Vestibular incision subperiosteal tunnel access (VISTA) technique with collagen membrane compared to VISTA alone for treatment of multiple gingival recession defects: In Vivo Study  Test group VISTA with collagen membrane  
 
Inclusion Criteria  
Age From  30.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  Millers class 1 and class 2 recession with width of keratinized gingiva more than 1 mm and systemically healthy patients who are not smokers and absence of any carious and non carious leison  
 
ExclusionCriteria 
Details  Patients who are not willing to give consent
Pregnant lactating women
Patients taking any medication known to interfere with the health or healing of periodontal tissue within 6 months of the study
Patient with history of periodontal surgery 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Alternation 
Blinding/Masking   Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Clinical attachment loss Recession depth Recession Width Recession Keratinized tissue thickness Keratinized tissue width Percentage if root coverage   Baseline 3 months 6 months 
 
Secondary Outcome  
Outcome  TimePoints 
Plaque index Gingival index   Baseline 3 months 6 months 
 
Target Sample Size   Total Sample Size="24"
Sample Size from India="24" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 3 
Date of First Enrollment (India)   12/02/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="2" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Gingival recession is a common condition that affects both dental function and aesthetics while inflammation is the main cause factors like thin gingival biotype malpositioned teeth  trauma abnormal frenum attachment and iatrogenic causes such as improper brushing or poorly designed dentures can also contribute.

Various surgical techniques are used for root coverage including free gingival grafts connective tissue grafts coronally advanced flaps and guided tissue regeneration among these the coronally advanced flap with connective tissue graft is considered the gold standard though it has drawbacks such as the need for donor tissue and possible postoperative discomfort

Minimally invasive tunneling methods like the Vestibular Incision Subperiosteal Tunnel Access  technique developed by Zadeh offer comparable outcomes with less trauma and faster healing 

VISTA involves creating a small access incision to elevate a subperiosteal tunnel and using coronally anchored sutures to stabilize tissues and promote healing

For root coverage various grafts and biomaterials including collagen membranes can be used collagen membranes support cell growth allow nutrient exchange are resorbable and promote wound healing while reducing the risk of infection or membrane exposure.

 
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