FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2025/11/097127 [Registered on: 10/11/2025] Trial Registered Prospectively
Last Modified On: 07/11/2025
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   The Power of Practice: Restoring Hand Function After Stroke 
Scientific Title of Study   Effect of Repetitive Functional Movements on Hand Dexterity and Grip Strength in Acute Stroke Patient: A Randomized Controlled Trial 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  ClinicalTrials.gov 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  YASHIKA MOTWANI 
Designation  Student(Intern) 
Affiliation  Pravara Institute Of Medical Sciences 
Address  Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Ahmadnagar
MAHARASHTRA
413736
India 
Phone  07796529454  
Fax    
Email  yashika.h.motwani@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  YASHIKA MOTWANI 
Designation  Student(Intern) 
Affiliation  Pravara Institute Of Medical Sciences 
Address  Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Ahmadnagar
MAHARASHTRA
413736
India 
Phone  07796529454  
Fax    
Email  yashika.h.motwani@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Madhur Kulkarni PT 
Designation  Associate Professor 
Affiliation  Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU 
Address  Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Dr APJ Abdul Kalam College Of Physiotherapy Pravara Institute Of Medical Sciences DU loni
Ahmadnagar
MAHARASHTRA
413736
India 
Phone  7588009063  
Fax    
Email  madhurkulkarni19@gmail.com  
 
Source of Monetary or Material Support  
Dr. Vitthalrao Vikhe Patil Pravara Rural Hospital Pravara Institute Of Medical Sciences Loni, Tal. Rahata, Dist. Ahmednagar, Maharashtra, India 413736 
 
Primary Sponsor  
Name  Yashika Motwani (self) 
Address  Pravara Medical Sciences Rahata, Loni, Ahmednagar, Maharashtra 413736 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Yashika Motwani  Dr. Vitthalrao Vikhe Patil Pravara Rural Hospital  Medicine Ward, In-Patient Department (IPD), Rural Medical College and Hospital, Pravara Institute of Medical Sciences (Deemed to be University), Loni, Taluka Rahata, Ahmednagar, Maharashtra – 413736, India
Ahmadnagar
MAHARASHTRA 
07796529454

yashika.h.motwani@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: I679||Cerebrovascular disease, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Hand Dexterity & Functional Training Protocol for Patients with Upper limb Paresis  The Group will be given repetitive functional training exercises along with standard Physiotherapy treatment for one week screening will be done Pre and Post one week 
Comparator Agent  Standard Physiotherapy Treatment   Screening will be done Pre and Post and the participants will receive Standard Physiotherapy Treatment for a week 
 
Inclusion Criteria  
Age From  30.00 Year(s)
Age To  80.00 Year(s)
Gender  Both 
Details  1. Acute stroke patient within 1 to 2 weeks of onset
2. Mild-to-moderate dexterity impairment
3. Box and Block Test greater than 1
4. Patients with upper limb involvement
5. Ability to follow simple instructions
6. Voluntary Control minimum grade 3
7. Participants who are willing to give informed written consent 
 
ExclusionCriteria 
Details  Any other Musculoskeletal or neurological condition affecting hand dexterity
Severe cognitive deficits
Chronic stroke patient
 
 
Method of Generating Random Sequence   Random Number Table 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant and Investigator Blinded 
Primary Outcome  
Outcome  TimePoints 
Hand Dexterity: Measured using the Box and Block Test (BBT)
Grip Strength: Assessed with a dynamometer
Functional Ability: Evaluated through Fugl-Meyer Assessment (FMA)
 
Baseline (pre-intervention) and at 1 week (post-intervention).
 
 
Secondary Outcome  
Outcome  TimePoints 
Barthel Index  aseline (pre-intervention) & at 1 week (post-intervention).
 
 
Target Sample Size   Total Sample Size="38"
Sample Size from India="38" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   25/11/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Stroke frequently results in upper limb dysfunction, with up to 80% of patients experiencing reduced hand dexterity and grip strength, which limits their ability to perform daily activities. Repetitive and task-specific rehabilitation is known to stimulate neuroplasticity and promote motor recovery. This randomized controlled trial aims to evaluate the effect of repetitive functional movements on hand dexterity and grip strength in acute stroke patients.

Thirty-eight participants will be randomly allocated into two groups. The Control group will receive conventional physiotherapy including passive and active range of motion exercises, balance and coordination training, strengthening exercises, gait training with assistive devices, and gentle stretching or yoga-based mobility exercises. The Experimental group will receive the same conventional therapy along with a structured Repetitive Functional Movement Training protocol consisting of progressive phases focusing on facilitation, skill development, and functional integration. Exercises include finger individuation, grip–release, fine motor and object manipulation tasks, and functional activities such as bottle opening, zipper training, and towel wringing.

Intervention will be given six sessions per week for one week. Outcome measures will include the Box and Block Test, hand-held dynamometer,Barthel Index, and Fugl-Meyer Assessment. The study anticipates greater improvement in hand dexterity and grip strength in the experimental group compared to the control group.

 
Close