The study titled ’Comparative Efficacy of Individualized Homoeopathic Medicines, Ruta Graveolans 30C and Physostigma 6C in progressive Myopia in children is a  single blind, randomized, comparative trial with the primary objective to assess changes in the progression rate of vision acuity in children with myopia and secondary objective is to assess changes in the progression rate of vision acuity in children with myopia. The duration of the study will be 2 years wherein duration of participation and intervention in the study shall be one year for individual participants. Participants of age 6- <10 years, both sexes with Refractive error of -1.00 D to -5.0 D without glasses and Minimum spherical equivalent (SE) -(minus)1D. (SE=sphere+1/2 cylinder) will be included in the study. Myopia related to retinal dystrophies or collagen syndromes, and developmental disorders, children suffering from illness like autism, intellectual diasbilities, ADHD, Congenital cataract, retinal detachment or myopic macular degeneration, children suffering from malnutrition which will be defined as standard deviation of < -1 SD of basic metabolic index according to Rastriye bal swasthya karyakaram chart for BMI chart for age 6 to 18 years (Z score), participants unable to come for regular fortnightly follow up and legally authorized reperesentative is unable to give consent for the homoeopathic treatment will be excluded. The primary outcome measure includes annual myopic progression rate to be assessed at baseline and every 3 months for 1 year by snellen chart. the secondary outcome measures include axial length, curvature changes and annual axial length progression rate to be assessed at baseline and 12 months after initiation of treatment.