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CTRI Number  CTRI/2025/10/096346 [Registered on: 22/10/2025] Trial Registered Prospectively
Last Modified On: 21/10/2025
Post Graduate Thesis  Yes 
Type of Trial  Observational 
Type of Study   Prospective case series study 
Study Design  Single Arm Study 
Public Title of Study   Explore effectiveness of homoeopathic management in Burnout syndrome in working professionals in age group 25 to 45 years. 
Scientific Title of Study   Exploring the role of Synthesis repertory in the homoeopathic management of Burnout syndrome in working professionals aged 25 to 45 years a prospective case series study. 
Trial Acronym  Nil  
Secondary IDs if Any  
Secondary ID  Identifier 
Nil  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Aashika Ashok Jain  
Designation  PG student  
Affiliation  Smt. K. B. Abad Homoeopathic Medical College  
Address  Smt.K.B. Abad Homoeopathic Medical College and Bhamasha shri V. D. Mehta, Dev Vijay Post graduate institute, Neminagar, Chandwad

Nashik
MAHARASHTRA
423101
India 
Phone  7066846606  
Fax    
Email  j.aashika12@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Mrs A S Pareek  
Designation  Professor  
Affiliation  Smt. K. B. Abad Homoeopathic Medical College  
Address  Smt.K.B. Abad Homoeopathic Medical College and Bhamasha shri V. D. Mehta, Dev Vijay Post graduate institute, Neminagar, Chandwad

Nashik
MAHARASHTRA
423101
India 
Phone  8669123226  
Fax    
Email  arpu_joshi@rediffmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Ajay Dahad  
Designation  Principal  
Affiliation  Smt. K. B. Abad Homoeopathic Medical College  
Address  Smt.K.B. Abad Homoeopathic Medical College and Bhamasha shri V. D. Mehta, Dev Vijay Post graduate institute, Neminagar, Chandwad

Nashik
MAHARASHTRA
423101
India 
Phone  9423929797  
Fax    
Email  drdahad@yahoo.com  
 
Source of Monetary or Material Support  
Nil  
 
Primary Sponsor  
Name  Dr Aashika Ashok Jain  
Address  Smt.K.B. Abad Homoeopathic Medical College and Bhamasha shri V. D. Mehta Dev Vijay Post graduate institute Neminagar Chandwad 423101 
Type of Sponsor  Other [Self sponsored ] 
 
Details of Secondary Sponsor  
Name  Address 
Nil  Nil 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Aashika Jain   Smt. K. B. Abad Homoeopathic Medical College   Department OPD of medicine Smt K. B. Abad Homoeopathic Medical College Neminagar Chandwad 423101
Nashik
MAHARASHTRA 
7066846606

j.aashika12@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Smt K B Abad Homoeopathic Medical College   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: Z730||Burn-out,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Nil  Nil 
 
Inclusion Criteria  
Age From  25.00 Year(s)
Age To  45.00 Year(s)
Gender  Both 
Details  1. Working professionals between age group 25 to 45 years of
any gender.
2. Diagnosed burnoutsymptoms based on a validated burnout
assessment scale i.e. CBI scale scoring.
3. Individuals willing to participate and provide informed
consent and participant had to be literate.
4. Those who have been experiencing burnout symptoms for
at least 3 months.
5. Individuals open to receiving homoeopathic treatment as
part of the study.  
 
ExclusionCriteria 
Details  1. Individuals below 25 years or above 45 years.
2. Participants diagnosed with severe psychiatric disorder eg.
depression bipolar disorder schizophrenia who had a
recent history over past 3 months of any psychiatric
medications.
3. Pregnant and lactating females.
4. Individuals currently undergoing allopathic or alternative
treatment for burnout management.
5. Participant unwilling to comply with follow up visits or
assessments. 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
The cases will be evaluated systematically using the Copenhagen Burnout
Inventory Scale. The evaluation process will be done at pre intervention and after follow ups post homoeopathic intervention.
Changes in scores post homoeopathic intervention will be remarked
improved and not improved. Improved means Relief of complaints and general
well being of patient. Not improved means No significant relief of complaints
after a sufficient period of treatment. 
At baseline Copenhagen Burnout Inventory Scale use to see the pre intervention score of burnout and after post intervention CBI scale will be used again and scores will be assessed.
scores will be used to assess changes in burnout levels.
Changes in scores post homoeopathic intervention will be remarked
improved and not improved.  
 
Secondary Outcome  
Outcome  TimePoints 
Nil  Nil 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   06/11/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="1"
Days="6" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary   Burnout is a syndrome resulting from exhaustion due to chronic job stress not managed successfully refers specially to phenomena in the occupational context. It is characterized by physical and emotional fatigue and sometimes physical illness. Frustration from perceived inability to end the stresses and problem associated with powerlessness in ones job
contribute to loss of concern for patient or client or good job performance. Under three dimensions it is characterized as feelings of energy depletion or exhaustion or increased mental distance from one job or feeling of negativity or cynicism related to their job a sense of ineffectiveness and lack of accomplishment. It may lead to job dissatisfaction and increase absenteeism in the workplace it also exacerbates drug and alcohol abuse and suicidal ideation and dependency.
It has been recognized by the World Health Organization .Studies indicate that burnout is widespread among
professionals across various sectors. For instance a systemic review revealed that more than one third of public health workers suffered from burnout which affects their mental and physical health. In healthcare
sector burnout rates among healthcare professionals in India are associated with increased risk .Younger age female gender unmarried status difficult working conditions were associated with increased risk of burnout. According to a systemic review and meta analysis found that close to one fourth of Indian healthcare professionals suffer from burnout. Burnout in health care workers particularly doctors has been shown to cause increase medical error and leading to dissatisfaction among patients deterioration in interpersonal relationship
Furthermore a study where IT professionals reported that 95 percent are experiencing burnout with higher prevalence among women.Homoeopathy with its fundamental
principle of Individualization emphasize that each patient requires a holistic treatment considering a person in disease and not disease of the person for prescribing homoeopathic medicine as it takes in account miasmatic background temperament and susceptibility to disease. By utilizing the Synthesis repertory from RADAR 10 software for remedy selection and the Copenhagen Burnout Inventory Scale for assessment the research seeks to provide evidence on the potential role of homoeopathy in reducing burnout symptoms and also contribute to diversification of options
available for burnout management.
Aim of study is to exploring the role of synthesis repertory in the homoeopathic management of burnout syndrome in working professionals aged 25 to 45 years .
Primary objective is to evaluate effectiveness of homoeopathic medicine in reducing symptoms of burnout in working professionals aged 25 to 45 years
using Synthesis repertory. Secondary Objective is to identify the most frequently indicated homoeopathic remedies for burnout using the Synthesis Repertory.
Study Design is a Prospective case series study.
Study Setting is Cases collected from OPD and IPD of institute of homoeopathic medical colleges. Camps conducted by the institute. Peripheral OPDs.
Patients from any working professionals like corporate employees healthcare workers and IT professionals and lawyers and teachers etc included in study. 
Patients between age group 25 to 45 years.
Patients diagnosed based on CBI Scale scoring as moderate to
severe burnout levels.
Duration of Study is 18 months.
Sample Size
Minimum 30 cases.
Sampling Technique is Purposive Sampling selecting individual based on predefined burnout criteria.
Data for this study will be collected using prospective approach. Using purposive sampling working professionals aged 25 to 45 years experiencing burnout symptoms will be selected. Participants will be screened using Copenhagen Burnout Inventory scale.Participant fulfilling inclusion criteria will be eligible for participation in study. A detailed case of each patient will be taken as per case record format. Confidentiality of participants will be maintained following ethical committee guidelines.The patient will be given well selected homeopathic remedy based on repertorisation done by Synthesis repertory using RADAR 10 software.The same measurement tool CBI scale will be used to track changes in symptoms and overall improvements post intervention with homoeopathic medicine.
Study instruments or Data collection tools will be Copenhagen Burnout Inventory scale and Case Record Format and RADAR 10 software Synthesis repertory. Homoeopathic Medicines .The cases will be evaluated systematically using the Copenhagen Burnout Inventory Scale. The evaluation process will be done at pre intervention and after follow ups post homoeopathic intervention scale scores will be used to assess changes in burnout levels.CBI Scale consists of three subscales . Personal burnout Work related
burnout Client or patient related burnout. Each item in scale is rated on 5 point Likert scale 0 means Never 25 means Rarely 50 mean Sometimes 75 means Often 100 means Always. The average score of each scale is computed.
Mild burnout is score less than 50 Moderate burnout means score 50 to 74 Severe burnout means score more than and equal to 75.
Changes in scores post homoeopathic intervention will be remarked improved and not improved. Improved means Relief of complaints and general well being of patient. Not improved means No significant relief of complaints after a sufficient period of treatment.
Data management and analysis procedure is after filling the case record format symptoms of the case will be
repertorized using Synthesis repertory from RADAR 10 software anddigitally stored for analysis. The pre and post homoeopathic intervention CBI scale score will be recorded and maintained using excel sheets. The analysis of the collected data will be done as per appropriate statistical tests to assess the effectiveness of homoeopathic intervention.
Plan for statistical analysis is analytical presentation of all the cases will be prepared.
Statistical technique will be appropriate charts and diagrams and tables will be used for data representation.
 
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