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CTRI Number  CTRI/2025/11/097733 [Registered on: 20/11/2025] Trial Registered Prospectively
Last Modified On: 20/11/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Drug
Ayurveda
Other (Specify) [post operative wound healing]  
Study Design  Randomized, Parallel Group, Active Controlled Trial 
Public Title of Study   EFFICACT OF CHEDANA PASHCHAT DURVA TAILA AND JATYADI TAILA APPLICATION IN MANAGEMENT OF KADARA (CORN). 
Scientific Title of Study   A RANDOMIZED COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF CHEDANA PASHCHAT DURVA TAILA AND JATYADI TAILA APPLICATION IN THE MANAGEMENT OF KADARA (CORN) 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  DR LAVANYA L 
Designation  PG SCHOLAR 
Affiliation  SIDRAMAPPA DANIGOND MEMORIAL TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE 
Address  OPD DEPARTMENT OF SHALYATANTRA FIRST FLOOR SDM TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE ,DR SIDDHANT NAGAR,TERDAL,BAGALKOT

Bagalkot
KARNATAKA
587315
India 
Phone  7892051369  
Fax    
Email  lavanyalnaik15@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  DR SUJATA B WADDAR 
Designation  PROFESSOR 
Affiliation  SIDRAMAPPA DANIGOND MEMORIAL TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE 
Address  OPD DEPARTMENT OF SHALYATANTRA FIRST FLOOR SDM TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE ,DR SIDDHANT NAGAR,TERDAL,BAGALKOT

Bagalkot
KARNATAKA
587315
India 
Phone  8105401470  
Fax    
Email  sujata.bw@gmail.com  
 
Details of Contact Person
Public Query
 
Name  DR SUJATA B WADDAR 
Designation  PROFESSOR 
Affiliation  SIDRAMAPPA DANIGOND MEMORIAL TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE 
Address  OPD DEPARTMENT OF SHALYATANTRA FIRST FLOOR SDM TRUSTS AYURVEDIC MEDICAL COLLEGE AND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE ,DR SIDDHANT NAGAR,TERDAL,BAGALKOT

Bagalkot
KARNATAKA
587315
India 
Phone  8105401470  
Fax    
Email  sujata.bw@gmail.com  
 
Source of Monetary or Material Support  
SIDRAMAPPA DANIGOND MEMORIAL TRUSTS AYURVEDIC MEDICAL COLLEGE AND DANIGOND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE DR SIDDANTH NAGAR TERDAL BAGALKOT KARNATAKA 587315 
 
Primary Sponsor  
Name  DR LAVANYA L 
Address  SIDRAMAPPA DANIGOND MEMORIAL TRUSTS AYURVEDIC MEDICAL COLLEGE AND DANIGOND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE DR SIDDANTH NAGAR TERDAL BAGALKOT KARNATAKA 587315 
Type of Sponsor  Other [] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DR LAVANYA L  PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE  OPD,DEPARTMENT OF SHALYA TANTRA,FIRST FLOOR,SDMT AMC DANIGOND POST GRADUATION CENTRE PADMA AYURVEDIC HOSPITAL AND RESEARCH CENTRE,DR SIDDHANT NAGAR,TERDAL,BAGALKOTE
Bagalkot
KARNATAKA 
7892051369

lavanyalnaik15@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
SDMAT AMC AYURVEDIC MEDICAL COLLEGE AND PADMA AYURVEDIC HOSPITAL INSTITUTIONAL COMITTEE FOR REASEARCH ON HUMAN SUBJECTS  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:L84||Corns and callosities. Ayurveda Condition: KADARAH,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Comparator ArmProcedure-lepa, लेप (Procedure Reference: DR SHAILAJA SHRINIVASAN,SHARANGADHRA SAMHITA ,CHAUKAMBHA ORIENTALIA,VARNASI,4 TH EDITION 2005,MADHYAMAKHANDA,9 TH CHAPTER,VERSE 183,PAGE NO 239, Procedure details: DEPENDING ON THE SITE OF CORN POSITION WILL BE GIVEN TO PATIENT . CHEDANA KARMA OF CORN WILL BE DONE TILL THE LEVEL OF THE BASE. HEAMOSTASIS WILL BE ACHEIVED . DRESSING WILL BE DONE WITH JATYADI TAILA LOCALLY OVER THE EXCISED WOUND.)
2Intervention ArmProcedure-lepa, लेप (Procedure Reference: ACHARYA VIDYADHARA SHUKLA AND PROFF.RAVIDATTA TRIPATI,CHARAKA SAMHITA PART 2,CHAUKAMBA SANSKRIT PRATISHTHANA ,DELHI.CHIKITSA STHA 25 TH CHAPTER,VERSE NO-93, PAGE NUMBER 615, Procedure details: DEPENDIN ON THE SITE OF CORN POSITION WILL BE GIVEN TO PATIENT . CHEDANA KARMA OF CORN WILL BE DONE TILL THE LEVEL OF THE BASE. HEAMOSTASIS WILL BE ACHEIVED . DRESSING WILL BE DONE WITH DURVA TAILA LOCALLY OVER THE ESCISED WOUND.)
 
Inclusion Criteria  
Age From  17.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  1. PATIENTS WITH CLINICAL SIGNS AND SYMPTOMS OF KADARA WILL BE INCLUDED FOR STUDY.
2.PATIENTS WITH THE AFE GROUP 17-70 YEARS IRRESPECTIVE OF GENDER WILL BE TAKEN.
3.PATIENT WILLING TO SIGNAND GIVE CONSENT . 
 
ExclusionCriteria 
Details  1.PATIENTS WITH HIV HBSAG TB DM HTN
2PATIENT WITH ANY OTHER ILLNES WHICH RESERCHER FEELS IT INTERFERES THE INTERVENTION OF THE STUDIES. 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Not Applicable 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
EFFECT OF TRIAL DRUG ON HEALING OF WOUND POST EXCISION OF KADARA  7TH DAY,14 TH DAY,21ST DAY,28 TH DAY  
 
Secondary Outcome  
Outcome  TimePoints 
SAFETY OF TRIAL DRUG AND ADVERSE DRUG REACTION OF SYMPTOMS OF KADARA  7TH DAY,14 TH DAY,21ST DAY,28TH DAY 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 3 
Date of First Enrollment (India)   01/12/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

India, a developing country where majority of the population lives in villages and engaged in manual work and careless about their foot care. Chances of trauma is more common in these people due to ignorance or due to poor economic condition they wear improper foot wear and defective foot ware and poor foot care can lead to many diseases. Among them the common one is Kadara.Kadara is explained under “Kshudra Rogas” which usually occurs at the site of constant pressure. Acharya Sushruta has explained Lakshanas of Kadara as Keelavat, Kathina( hard), Granthi Madhya Unnata( raised in middle), Kolamatra( kolaphala ) in size, Ruk (pain), Srava( discharge)Kadara can be correlated to corn.

Corn is localized hyperkeratosis of the skin. It can be painful particularly when rubbed orwhen the pressure is put on the site. Corn has a deep central core which reaches to the deeper layers of the skin. Hyperkerotic lesions of the foot (corns and calluses) have been reported to affect 33-68% of people aged 65 or older. It is usually white/ yellow/grey in color and is common in females. Most of them are hard corns and soft corns occur in between the toes.Few preventive measures  such as soft shoes or soft pads at pressure point of the sole and treatments like local application of salicylic acid on corn, use of corn plaster and lastly excision of the corn. So we need a conventional method to encounter these problems more effectively.

 So here an attempt is made to evaluate the efficacy of Durva taila application after Chedana Karma over Jatyadi Taila application in the management of Kadara (corn).

 
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