| CTRI Number |
CTRI/2025/10/096711 [Registered on: 31/10/2025] Trial Registered Prospectively |
| Last Modified On: |
31/10/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Ayurveda |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
A clinical study on relief from Ajeerna (Indigestion) using Jeerak (Jeera) and Pashchimottanasana |
|
Scientific Title of Study
|
Clinical Evaluation of Jeerak and Pashchimottanasana Practice in Ajeerna (Indigestion) |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Yudhi Sharma |
| Designation |
MD Scholar |
| Affiliation |
Uttaranchal Ayurvedic College |
| Address |
Department of Swasthavritta and Yoga, Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand, India
Dehradun
UTTARANCHAL
248009
India |
| Phone |
8958153491 |
| Fax |
|
| Email |
yudhisharma1339@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Smita Zambare |
| Designation |
HOD |
| Affiliation |
Department of Swasthavritta and Yoga, Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand, India |
| Address |
Department of Swasthavritta and Yoga, Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand, India
Dehradun
UTTARANCHAL
248009
India |
| Phone |
8879133317 |
| Fax |
|
| Email |
smitazambare1@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Smita Zambare |
| Designation |
HOD |
| Affiliation |
Department of Swasthavritta and Yoga, Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand, India |
| Address |
Department of Swasthavritta and Yoga, Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand, India
UTTARANCHAL
248009
India |
| Phone |
8879133317 |
| Fax |
|
| Email |
smitazambare1@gmail.com |
|
|
Source of Monetary or Material Support
|
| Uttaranchal Ayurvedic College and Hospital,17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand 248009, India |
|
|
Primary Sponsor
|
| Name |
Yudhi Sharma |
| Address |
Uttaranchal Ayurvedic College, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand 248009 |
| Type of Sponsor |
Other [Self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Yudhi |
Uttaranchal Ayurvedic College, |
Department of Swasthavritta and Yoga,Uttaranchal Ayurvedic College and Hospital, 17, Old Mussoorie Rd, Kairwaan Gaon, Dehradun, Uttarakhand 248009, India
Dehradun
UTTARANCHAL |
8958153491
yudhisharma1339@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethical Committee of Uttaranchal Ayurvedic College |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:K30||Functional dyspepsia. Ayurveda Condition: AJIRNAM, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Drug | Classical | | (1) Medicine Name: Jeerak, Reference: Su. Su. 46/229, Route: Oral, Dosage Form: Dravaka, Dose: 1(g), Frequency: bd, Bhaishajya Kal: Pragbhakta, Duration: 2 Months, anupAna/sahapAna: Yes(details: -Ushna Jal), Additional Information: -Patients registered for the study will be provided 1 g roasted Jeerak seed packets. In the procedure, patients will be advised to chew the Jeerak seeds followed by lukewarm water orally. The drug will be administered to 50 patients over a period of 2 months. Patients will be instructed to follow up every 15 days during this period. |
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
50.00 Year(s) |
| Gender |
Both |
| Details |
1.Individuals having digestive problems.
2.Individuals who were fully cooperative for the study.
3.Individuals with informed consent to participate in the study. |
|
| ExclusionCriteria |
| Details |
1.Individuals not willing for the trial.
2.Patients suffering from gastroesophageal reflux disease (GERD), peptic ulcers, irritable
bowel syndrome (IBS), Crohn’s disease, and ulcerative colitis.
3. Patients undergoing any abdominal surgical procedures.
4. Patients not addicted to tobacco, smoking and alcohol.
5. Individual who’s taking any medicine for digestion and acidity.
6. Individuals who take any medicine for digestion, constipation and acidity during this
study of 60 days. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To assess the combined effect of jeerak and pashchimottanasana in patients of ajeerna. |
1. Baseline at day 1 before onset of treatment.
2. Follow up after every 15 days.
3. 2 months after onset of treatment.
|
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="50"
Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
08/12/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="2"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Ajeerna is a digestive disorder that develops due to the improper digestion of food, leading to symptoms like anorexia, constipation, nausea. This clinical study aims to evaluate the combined effect of Jeerak and Pashchimottanasana practice in patients suffering from Ajeerna. Data will be collected at the baseline and after 2 months of intervention. Patients will be advised to follow up every 15 days during the 2-month study period for regular monitoring and assessment of clinical progress. |