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CTRI Number  CTRI/2025/12/099584 [Registered on: 22/12/2025] Trial Registered Prospectively
Last Modified On: 21/12/2025
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Yoga & Naturopathy 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Effect of Integrated Yoga Module on Mental Health and Quality of Life in Cancer Patients 
Scientific Title of Study   Effect of an Integrated Yoga Module on Mental Health and Quality of Life in Cancer Patients: A Randomized Controlled Trial 
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Ishani 
Designation  PhD Scholar 
Affiliation  University of Patanjali 
Address  Department of Yoga Science, University of Patanjali
Haridwar Uttrakhand
Hardwar
UTTARANCHAL
249405
India 
Phone  9068501683  
Fax    
Email  ishanithakur@uop.edu.in  
 
Details of Contact Person
Scientific Query
 
Name  Dr Monika Sharma 
Designation  Assistant Professor 
Affiliation  University of Patanjali 
Address  Department of Yoga Science, University of Patanjali
Haridwar Uttrakhand
Hardwar
UTTARANCHAL
249405
India 
Phone  9412937920  
Fax    
Email  drmonikasharma@uop.edu.in  
 
Details of Contact Person
Public Query
 
Name  Ishani 
Designation  PhD Scholar 
Affiliation  University of Patanjali 
Address  Department of Yoga Science, University of Patanjali
Haridwar Uttrakhand
Hardwar
UTTARANCHAL
249405
India 
Phone  9068501683  
Fax    
Email  ishanithakur@uop.edu.in  
 
Source of Monetary or Material Support  
Department of Yoga Science, University of Patanjali, Haridwar, Uttarakhand, India, 249405 
 
Primary Sponsor  
Name  University of Patanjali 
Address  Department of Yoga Science, University of Patanjali, Haridwar, Uttarakhand, India, 249405 
Type of Sponsor  Other [University] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Deepak Singla  Indus International Hospital  Chandigarh Ambala Road, Dera Bassi, Mohali
Chandigarh
CHANDIGARH 
9068501683

deepak.singla02@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 2  
Name of Committee  Approval Status 
Indus International Hospital- Institutional Ethics Committee (IIH-IEC)  Approved 
Institutional Ethics Committee, University of Patanjali, Haridwar, Uttarakhand  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: C00-D49||Neoplasms,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Integrated Yoga Module  Om chanting, gayatri mantra, maha mrityunjay mantra, karatala sakti vikasaka, angulamula sakti vikasaka, kaphonisakthi vikasaka, manibandha sakti vikasaka, trataka, ashwani mudra, kaki mudra, bhastrika pranayama, nadi shodhana, sheetli pranayam, bhramri pranayam, Haasyasana, shavasana, swadhyaya,Ishvarapranidhana for 123 days and 60 mins per day 
Comparator Agent  Usual care   Usual care  
 
Inclusion Criteria  
Age From  50.00 Year(s)
Age To  75.00 Year(s)
Gender  Both 
Details  Diagnosed with solid tumor malignancy
Currently receiving chemotherapy treatment
Life expectancy less then equals to 6 months
Able to provide informed consent
 
 
ExclusionCriteria 
Details   
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Anxiety, Depression, Quality of Sleep, Cognitive Emotion Regulation Questionnaire, Quality of Life  Pre-Data: January
Post-Data: April 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="136"
Sample Size from India="136" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   06/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

This research examines how a structured yoga program can help cancer patients manage psychological stress during chemotherapy. Cancer patients often face significant anxiety, depression, sleep problems, and difficulty coping with their emotions while receiving treatment. Current approaches mainly use medications, which can cause additional side effects and dependency issues.

Our study offers a 12-week integrated yoga program specifically designed for patients undergoing active chemotherapy. The program combines gentle physical postures, breathing exercises, meditation, and mindfulness practices adapted to suit the physical limitations and needs of cancer patients. We aim to see whether this yoga intervention can meaningfully reduce anxiety and depression, improve sleep quality, enhance emotional coping skills, and boost overall quality of life.

The study will enroll 136 cancer patients from various cancer types who are currently receiving chemotherapy. Participants will be randomly assigned to either receive the yoga program immediately or continue with usual care and receive yoga after the study ends. We will measure changes in mental health, sleep, emotion regulation, and quality of life at the beginning and after 12 weeks.

This research addresses a critical gap because most previous studies focused only on breast cancer survivors after treatment ended, not on diverse cancer patients during the challenging active treatment phase. By understanding how yoga helps patients cope during chemotherapy, we hope to provide evidence-based support that can be integrated into routine cancer care to improve patients’ well-being alongside their medical treatment.

 
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