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CTRI Number  CTRI/2025/09/094602 [Registered on: 11/09/2025] Trial Registered Prospectively
Last Modified On: 11/09/2025
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   Cross Sectional Study 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Revised Cross-sectional Growth Curves for Height Weight and Body Mass Index 
Scientific Title of Study   Development of Updated Growth References for Indian Children and Adolescents (0–18 Years): A Multicenter Cross-Sectional Study 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Anuradha Khadilkar  
Designation  Deputy Director  
Affiliation  Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) 
Address  Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Pune
MAHARASHTRA
411001
India 
Phone  08975230213  
Fax    
Email  anuradhavkhadilkar@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Anuradha Khadilkar  
Designation  Deputy Director  
Affiliation  Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) 
Address  Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Pune
MAHARASHTRA
411001
India 
Phone  08975230213  
Fax    
Email  anuradhavkhadilkar@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Anuradha Khadilkar  
Designation  Deputy Director  
Affiliation  Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) 
Address  Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Lower Ground Floor, Jehangir Hospital, 32 Sassoon Road, Pune, Maharashtra, India
Pune
MAHARASHTRA
411001
India 
Phone  08975230213  
Fax    
Email  anuradhavkhadilkar@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  HCJMRI 
Address  33, Sassoon Road, Jehangir Hospitals, Pune, Maharashtra,411001 
Type of Sponsor  Research institution 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 11  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Chirantap Oza   EndoGrow Pediatric and Adolescent Endocrine Center  205 vision Complex, Besides legends of punjab,Panjrapole char rasta, Ambawadi, Ahmedabad 380015.
Ahmadabad
GUJARAT 
9023094004

chirantap@gmail.com 
Dr Saurabh Uppal  Growth Clinic  First floor,192 Gujral Nagar, Jalandhar city, 144001
Jalandhar
PUNJAB 
9357493570

drsaurabhuppal@gmail.com 
Dr Hriday De  Institute of Child Health  11,Dr. Biresh Guha Street, Kolkata- 700017, Park Circus, Kolkata, West Bengal , Ground Floor , Project Room (Room No. 113)
Kolkata
WEST BENGAL 
97358 46215

hridayde2010@gmail.com 
Dr Shaila Pachapure   KLEs Dr. Prabhakar Kore hospital  Quarter A14/8, JNMC campus, Behind dental college, Nehru Nagar, Belagavi 590010
Belgaum
KARNATAKA 
9632446393

drshailams@gmail.com 
Dr Vijay Jaiswal   LLRM medical college  Dr Anupama Verma-Head of Department Pediatric, LLRM medical college, Meerut, UP, Pin 250004
Meerut
UTTAR PRADESH 
9808959959

kinjalvijay@yahoo.com 
Dr Hemchand Prasad  Mehta Multispeciality Hospitals India Pvt Ltd  No.2, McNichols Road, 3rd Lane, Chetpet, Chennai-600031
Chennai
TAMIL NADU 
9884984280

pediatricendocrinology.mehta@gmail.com 
Dr Nikhil Shah  Sai kripa childrens hospital  Road no 1, Opp bmc office, Chembur, Mumbai 400071
Mumbai
MAHARASHTRA 
9833443740

nikhilshah1507@gmail.com 
Dr Aashish Sethi  Shri Mahant Indresh Hospital  House no 20, Lane no 2,Dron puri, GMS ROAD, Dehradun, 248001
Dehradun
UTTARANCHAL 
9818038469

Dr.aashishsethi@gmail.com 
Dr Kiran Meena  ShriKripa Clinics  31,32, SKIT college road, Ramanagaria, Jagatpura, Jaipur -302017
Jaipur
RAJASTHAN 
7733066261

drkiran2172@gmail.com 
Dr Nikhil Lohiya  Silver Lining Pediatric Super Specialty Center  2nd Floor, K K Business Plaza, Lokmat Square, Ramdaspeth Nagpur- 440010
Nagpur
MAHARASHTRA 
7358565686

drnnlohiya@gmail.com 
Dr Ankita Maheshwri  Sri Aurobindo medical college and post graduate institute  222, 2 nd floor , benchmark building, Opposite Satya Sai school Satya Sai square, Indore (Madhya Pradesh) 452010
Indore
MADHYA PRADESH 
7046370787

ankitamaheshwari23@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Jehangir Clinical Development Center Pvt. Ltd.   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Without any comorbidities  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Nil  Nil 
 
Inclusion Criteria  
Age From  1.00 Day(s)
Age To  18.00 Year(s)
Gender  Both 
Details  Healthy volunteers  
 
ExclusionCriteria 
Details  Without any comorbidity 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
For the first time growth references will be available for Indian children from 0-5 years.
Updated references will be available for 5-18 year old Indian children
 
Baseline 
 
Secondary Outcome  
Outcome  TimePoints 
These data will be useful not only for clinical growth monitoring but also for researchers.
 
Yearly data  
 
Target Sample Size   Total Sample Size="31122"
Sample Size from India="31122" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="1"
Days="1" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - YES
  1. What data in particular will be shared?
    Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).

  2. What additional supporting information will be shared?
    Response -  Study Protocol
    Response -  Statistical Analysis Plan
    Response - Informed Consent Form

  3. Who will be able to view these files?
    Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.

  4. For what types of analyses will this data be available?
    Response - For individual participant data meta-analysis.

  5. By what mechanism will data be made available?
    Response - Proposals should be directed to [anuradhavkhadilkar@gmail.com].

  6. For how long will this data be available start date provided 02-12-2027 and end date provided 02-01-2030?
    Response - Beginning 9 months and ending 36 months following article publication.

  7. Any URL or additional information regarding plan/policy for sharing IPD? 
    Additional Information - NIL
Brief Summary  

Growth monitoring is a vital component of child health assessment, serving as an early indicator of nutritional status and growth-related disorders. While international growth references, such as the WHO Child Growth Standards (for children under five), WHO Growth References (for ages 5–19) and the 2015 IAP growth charts are commonly used in India, they may not accurately reflect the growth of present day Indian children. Several studies have highlighted the limitations of applying global/ dated standards to Indian populations, including the risk of overestimating undernutrition.

Existing Indian growth references, such as those developed by Agarwal et al. (1992), Khadilkar et al. (2009, 2012), and the IAP Growth Charts (2015), have contributed significantly to pediatric growth assessment in India. However, these data were primarily derived from older cohorts and urban, affluent populations. They may not adequately capture recent secular trends in growth patterns, especially in the context of India’s ongoing nutrition transition and the rising prevalence of overweight and obesity in children and adolescents.

The absence of up-to-date, comprehensive, and nationally representative growth references limits the accuracy of nutritional assessments and hinders effective public health planning. Therefore, there is a clear and urgent need to develop updated growth reference data for Indian children and adolescents aged 0–18 years, based on contemporary anthropometric measurements. Such data will enhance clinical decision-making and provide a robust foundation for nutrition policies, school health programs, and research.


 
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