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CTRI Number  CTRI/2025/07/091844 [Registered on: 28/07/2025] Trial Registered Prospectively
Last Modified On: 26/07/2025
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Dentistry
Nutraceutical 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Studying how Green Tea, Chamomile Tea, and Moringa Tea affect cavity-causing bacteria in the saliva of young adults 
Scientific Title of Study   Evaluating the antibacterial effects of widely available Green tea, Chamomile tea and Moringa tea on salivary Streptococcus Mutans Level: An in vivo Study 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Paras 
Designation  Undergraduate 
Affiliation  Faculty of Dental Sciences, SGT University, Gurugram 
Address  room no 204, Department of Conservative Dentistry and Endodontics, Faculty of dental Sciences, SGT University

Gurgaon
HARYANA
122001
India 
Phone  8607517787  
Fax    
Email  paraskk1311@gmail.com  
 
Details of Contact Person
Scientific Query  
Name  Dr Akanksha Joon 
Designation  Assistant Professor 
Affiliation  Faculty of Dental Sciences, SGT University, Gurugram 
Address  room no 204, Department of Conservative Dentistry and Endodontics, Faculty of dental Sciences, SGT University

Gurgaon
HARYANA
122001
India 
Phone  9971167340  
Fax    
Email  joonakanksha@gmail.com  
 
Details of Contact Person
Public Query  
Name  Dr Akanksha Joon 
Designation  Assistant Professor 
Affiliation  Faculty of Dental Sciences, SGT University, Gurugram 
Address  room no 204, Department of Conservative Dentistry and Endodontics, Faculty of dental Sciences, SGT University

Gurgaon
HARYANA
122001
India 
Phone  9971167340  
Fax    
Email  joonakanksha@gmail.com  
 
Source of Monetary or Material Support  
No external monetary or material support. The study will be self funded by the Principal Investigator and conducted using the internal resources at SGT University, Gurugram 
 
Primary Sponsor  
Name  SGT University Gurugram 
Address  SGT University Chandu-Budhera, Gurugram-Badli Road Budhera, Gurugram – 122505 Haryana, India  
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Akanksha Joon  SGT University  Room no. 204, Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, SGT University, Budhera, Gurugram
Gurgaon
HARYANA 		 9971167340

joonakanksha@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committe SGT Dental College Hospital and Research Institute  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: K026||Dental caries on smooth surface,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Chamomile Tea Group  1 tea bag in 1 cup of boiling water, consumed once daily after breakfast 
Comparator Agent  Chlorhexidine Gluconate 0.2% Mouthwash  10 mL twice daily after brushing 
Intervention  Green Tea (Camellia sinensis)  1 tea bag in 1 cup of boiling water, consumed once daily after breakfast 
Intervention  Moringa Tea Group  1 tea bag in 1 cup of boiling water, consumed once daily after breakfast 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  24.00 Year(s)
Gender  Both 
Details  1.Participants not consuming these herbal tea prior to study.
2.Not associated with any systemic disease.
3.No history of receiving fluoride mouthwash or varnish for at least one month before sampling
 
 
ExclusionCriteria 
Details  1.Those undergoing antibiotic therapy.
2.Presence of rampant caries, soft tissue lesions, and localized/ generalized active periodontitis.
3.History of usage of any medication or antimicrobial mouthwash like CHG and participants who had prosthetic-orthodontic appliances.
 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant and Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
The primary outcome of this study is the change in the salivary Streptococcus mutans count from baseline to post-intervention, measured quantitatively after the participants have consumed the assigned tea intervention for the specified study duration.  Baseline (Day 0 – before intervention)

1 Week post-intervention

1 Month post-intervention

6 Months post-intervention

1 Year post-intervention 
 
Secondary Outcome  
Outcome  TimePoints 
nil  nil 
 
Target Sample Size   Total Sample Size="60"
Sample Size from India="60" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

This in vivo study aims to evaluate and compare the antibacterial effects of three commonly available herbal teas—Green tea, Chamomile tea, and Moringa tea in comparison to Chlorhexidine gluconate on the salivary levels of Streptococcus mutans, a primary contributor to dental caries. Healthy participants will be randomly assigned to one of the four intervention groups each consuming a specified quantity of the assigned tea daily over a fixed period. Unstimulated saliva samples will be collected at baseline and post-intervention to quantify changes in S. mutans using qPCR (Real time Polymerase chain reaction) technique for each participant. . The study seeks to identify which of the three herbal teas demonstrates the most effective reduction in salivary S. mutans levels, potentially contributing to the development of natural, preventive oral health strategies.

 
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