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CTRI Number  CTRI/2025/07/091989 [Registered on: 30/07/2025] Trial Registered Prospectively
Last Modified On: 17/07/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Medical Device 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Comparison of two ultrasound guided approaches for cannulation Of neck vein which is internal jugular vein in adult patients undergoing surgery.  
Scientific Title of Study   Comparison of Short Axis Approach with Dynamic Needle Tip Positioning and Oblique Axis Approach for ultrasound guided cannulation Of Internal Jugular Vein in adult patients undergoing elective surgery under general anaesthesia. 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Pooja 
Designation  Post Graduate student 
Affiliation  Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital 
Address  room no 301 3rd floor Department of anaesthesia, ABVIMS and Dr. RML hospital, Baba Kharak Singh marg, near gurudwara Bangla sahib, connaught place, New Delhi

New Delhi
DELHI
110001
India 
Phone  7087790662  
Fax    
Email  heena51197@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Neerja Banerjee 
Designation  Professor and Head of department 
Affiliation  Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital 
Address  room no 301 3rd floor Department of anaesthesia, ABVIMS and Dr. RML hospital, Baba Kharak Singh marg, near gurudwara Bangla sahib, connaught place, New Delhi

New Delhi
DELHI
110001
India 
Phone  9810517575  
Fax    
Email  neerja.banerjee@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Aanchal Kakkar 
Designation  Professor 
Affiliation  Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital 
Address  room no 301 3rd floor Department of anaesthesia, ABVIMS and Dr. RML hospital, Baba Kharak Singh marg, near gurudwara Bangla sahib, connaught place, New Delhi

New Delhi
DELHI
110001
India 
Phone  9899368080  
Fax    
Email  kakkaraanchal02@gmail.com  
 
Source of Monetary or Material Support  
Department of Anaesthesia, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital, Baba Kharak Singh marg, New Delhi, Delhi, India, pin 110001 
 
Primary Sponsor  
Name  Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital 
Address  Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia hospital, Baba Kharak Singh Marg, Connaught place, New Delhi 110001 
Type of Sponsor  Government medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Pooja  Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital   Department of Anaesthesia, Kharak Singh Marg, near Bangla Sahib, Connaught place
New Delhi
DELHI 
7087790662

heena51197@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee ABVIMS and Dr. RML hospital, New Delhi  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: O||Medical and Surgical,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Oblique axis approach for ultrasound guided cannulation of internal jugular vein   Oblique axis approach for ultrasound guided cannulation Of Internal Jugular Vein in adult patients undergoing elective surgery under general anaesthesia 
Comparator Agent  Short Axis Approach with Dynamic Needle Tip Positioning for Ultrasound guided cannulation of Internal Jugular Vein   Short Axis Approach with Dynamic Needle Tip Positioning for ultrasound guided cannulation Of Internal Jugular Vein in adult patients undergoing elective surgery under general anaesthesia  
Intervention  Ultrasound guided cannulation of internal jugular vein   Short Axis Approach with Dynamic Needle Tip Positioning and Oblique Axis approach for ultrasound guided cannulation Of Internal Jugular Vein in adult patients undergoing elective surgery under general anaesthesia. Total duration of procedure will be taken as time from skin puncture to confirmed intraluminal guidewire or catheter placement which is first attempt success rate.The total duration of IJV cannulation is expected to be approximately 3–5 minutes under ultrasound guidance in a single successful attempt. In case of difficulty or multiple attempts, the duration may extend, but no fixed upper time limit is defined in the study protocol. 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  99.00 Year(s)
Gender  Both 
Details  adult patients including both gender (Age 18 year or older), ASA class I, II, III, scheduled for elective surgery under general anaesthesia requiring internal jugular vein cannulation will be enrolled for the study. 
 
ExclusionCriteria 
Details  1. Patients with coagulopathy
2. Thrombosed right IJV
3. History of previous cannulation of IJV
4. Patients on anticoagulant drugs
5. BMI greater than 30
6. Patients with tracheostomy
7. Patients with neck scar near right IJV
 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
First attempt success rate  At baseline 
 
Secondary Outcome  
Outcome  TimePoints 
successful cannulation time  At baseline 
number of attempts for successful cannulation  Total number of attempts taken for placement of catheter at baseline 
complications like hematoma, posterior wall puncture, vasospasm etc  At baseline 
 
Target Sample Size   Total Sample Size="104"
Sample Size from India="104" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   20/08/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="5"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

The purpose of this study is to compare two ultrasound guided techniques for placing a central line into the internal jugular vein in adults having elective surgery under general anesthesia. It aims to find out which method is more successful on the first attempt, takes less time, needs fewer attempts, and has fewer complications. This study will include patients who need internal jugular vein cannulation. After explaining the procedure, written consent will be obtained from the patient or their relatives. Patients will be randomly divided into two groups using sealed envelopes. Standard monitoring will include ECG, blood pressure, and oxygen levels. General anesthesia will be given using propofol, fentanyl, and vecuronium. After intubation, anesthesia will be maintained with oxygen, nitrous oxide, and sevoflurane. Cannulation will be done on the right internal jugular vein with the patient in a slight head-down position and the head turned to the opposite side. The procedure will be guided by real-time ultrasound using a high-frequency probe. Group I which is Short Axis with Dynamic Needle Tip Positioning, the ultrasound probe will show a cross-sectional view of the vein. The needle will be advanced slowly in small steps while keeping the tip visible on the screen. Once the tip is inside the vein and blood return is seen, a guidewire will be inserted. The needle will be removed, the path will be widened, and a catheter will be placed over the guidewire. Group II which is Oblique Axis Approach, an oblique view of the vein will be used. The needle will be inserted in line with the ultrasound beam, so the entire needle is visible. The needle will be guided into the vein while continuously watching the tip. Once blood return is confirmed, the guidewire, dilator, and catheter will be placed as in the first group. After the procedure, an X-ray or ultrasound will be used to confirm catheter position and rule out complications. Data collected will include patient details, reason for cannulation, success on first attempt, number of attempts, use of ultrasound, time taken, and any complications like artery puncture, hematoma, pneumothorax, misplacement, or infection.

 
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