| CTRI Number |
CTRI/2026/02/104477 [Registered on: 23/02/2026] Trial Registered Prospectively |
| Last Modified On: |
19/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Yoga & Naturopathy
Preventive
Behavioral |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
The role of Bhramari Pranayam in reducing depression Among college going students |
|
Scientific Title of Study
|
Study the effect of Bhramari Pranayam for management of depression in college going students |
| Trial Acronym |
nil |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Prajwal Jivanrao Deshmukh |
| Designation |
PG Scholar |
| Affiliation |
BVDU College of Ayurved and Hospital |
| Address |
Bharati Vidyapeeth Deemed To Be University Department Of Kriya Sharira College Of Ayurved Dhankawadi Katraj Pune 411043
Pune
MAHARASHTRA
411043
India |
| Phone |
7448282252 |
| Fax |
|
| Email |
prajwaldeshmukhpd77@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Kavita Indapurkar |
| Designation |
Professor and HOD |
| Affiliation |
BVDU College of Ayurved and Hospital |
| Address |
Bharati Vidyapeeth Deemed To Be University Department Of Kriya Sharira College Of Ayurved Dhankawadi Katraj Pune 411043
Pune
MAHARASHTRA
411043
India |
| Phone |
9890791688 |
| Fax |
|
| Email |
kavita.indapurkar@bharatividyapeeth.edu |
|
Details of Contact Person
Public Query
|
| Name |
Dr Kavita Indapurkar |
| Designation |
Professor and HOD |
| Affiliation |
BVDU College of Ayurved and Hospital |
| Address |
Bharati Vidyapeeth Deemed To Be University Department Of Kriya Sharira College Of Ayurved Dhankawadi Katraj Pune 411043
Pune
MAHARASHTRA
411043
India |
| Phone |
9890791688 |
| Fax |
|
| Email |
kavita.indapurkar@bharatividyapeeth.edu |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
Dr Prajwal Jivanrao Deshmukh |
| Address |
Sai Nagar lane no 3 samarth angan apartment |
| Type of Sponsor |
Other [self] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Prajwal Jivanrao Deshmukh |
Bharati vidyapeeth college of ayurved pune |
Bharati Vidyapeeth Deemed To Be University Department Of Kriya Sharira College Of Ayurved Dhankawadi Katraj Pune 411043
Pune
MAHARASHTRA |
7448282252
prajwaldeshmukhpd77@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics committee Bharati Vidyapeeth Deemed To Be University College Of Ayurved Pune |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
healthy participants 50(male/female) with age group 18 year to 24 year
|
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Procedure | - | Bhramari Pranayam | (Procedure Reference: Hathyog Pradipika, Procedure details: Sit in comfortable position with spine straight & shoulder relaxed close your eyes & take a few normal breaths place your index finger on the cartilage of your & gently press the ear flaps to block external sound alternatively you can place your thumb on the forehead & let your other fingers gently rest over the eyes & cheeks take a deep breath in through your nose filling your lungs completely with air as you exhale produce a humming sound similar to the buzzing of a bee the sound should come from throat not from mouth complete the exhalation & then inhale deeply again repeat 5 to 10 rounds per day for 12 weeks)
|
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
24.00 Year(s) |
| Gender |
Both |
| Details |
College going students age group 18-24 years. Individuals of Either gender.
Individuals having HAM-D [Hamilton Depresssion Rating Scale] score less than 13 |
|
| ExclusionCriteria |
| Details |
Individuals suffering from any known major physical or psychological illness.
Individuals who are doing Pranayama regularly.
Individuals taking medication for psychological illness. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| The study may reveal a change in the severity of depression as measured by the Hamilton Depression Rating Scale (HAM-D) score from baseline to 12 weeks after the Bhramari Pranayama intervention. |
Depression will be monitored before and after yoga intervention during baseline 7th day 15th day 30th day 45th day |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Study may reveal change in HAM D score from baseline to 12 weeks |
Depression will be monitored before & after yoga intervention at baseline duration of 7th day 15th day 30th day 45th day |
|
|
Target Sample Size
|
Total Sample Size="50"
Sample Size from India="50"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 2 |
|
Date of First Enrollment (India)
|
02/03/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="1"
Months="0"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Participants between the ages of 18 to 24 years were included in the study. They were informed about Bhramari Pranayama, including its procedure, as well as its potential positive and negative impacts. Informed consent was obtained from all participants prior to the initiation of the study.It was ensured that all participants had a score of less than 13 on the Hamilton Depression Rating Scale (HDRS), confirming eligibility for participation. Follow-up sessions have been scheduled at intervals of 7, 15, 30, and 45 days. Data will be collected during each follow-up, and the records will be maintained systematically.The collected data will be statistically analyzed and interpreted, and the final results will be presented accordingly. |