Rational for Selection of intervention/justification for Selection of trial drugs    Panchavalkala is one of the compound regimen popularly used and prescribed in the 6 classics for various gynecological disorders specially leucorrhoea uterine diseases and cervical erosions and also for wounds and ulcers in other parts of body The combination of the barks of 5 medicinal plants namely Vata (Ficus bengalensis) Udumbara (Ficus glomerata) Ashwatha ( Ficus religiosa ) Plaksha ( Ficus infectoria) Parisha ( Thespia populnea) in equal proporations is known as the Classical Panchavalkala Panchvalkala is having properties like Kashaya Rasa Sheetavirya Katuvipaka Panchvalkala have the best antibacterial and antifungal activity

Triphala is mild non habit forming and rejuvenative and hence recommenced for all It exhibits antiviral antibacterial antifungal antiallergic propertiesTriphala and its constituents act as improve blood circulation It shows immunomodulatory properties and helps in improving the body defence mechanism I have kashaya Rasa madhurvipaka Tridoshar Azadirachta indica is known to possess anti inflammatory antipyretic antimicrobial ant diabetic and diverse pharmacological properties It have Tikata kashaya Rasa laghu Guna Sheetavirya katuvipaka kandhughana prabhav  pitta kaphahar Dosha karma  Anti inflammatory and anti microbial activities of the root bark and leaves of A Indica Neem (Azadirachta indica) seed and leaf extracts have spermicidal anti microbial antifungal and antiviral properties They are also immuno modulatory that induce primarily a TH1 type response Honey has anti bacterial property Honey has well established function as an effective antibacterial agent with a broad spectrum of activity against Gram positive and Gram negative bacteria Some studies suggest that the topical use of honey may reduce odors swelling and scarring when used to treat wounds It have Madhura Rasa kasha anurasa ruksha Guna tridosha shamaka Sphatika has styptic and astringent properties It also acts as adjuvant It have kashaya kattu amala Rasa ushanavirya kandu tridoshanashak yonisankochak raktastravarodhaka

Haridra acts as an anti inflammatory antidiabetic anti diarrhoeal Hypolipidemic Hepatoprotective Anti cancerous It have Tikt Katu Rsa Ruksh  Laghu Guna Ushnavirya Katuvipak Kusthaghan Prabhav Kpha vat shamak dosha karma Vidanga is a useful herb to manage worm infestation that includes threadworms roundworms and types of worms due to its karimighna property It have Katu Kashya Rasa Laghu Ruksha Tikshna Guna Ushna virya Katu Vipaka Krimighna Prabhav Kapha Vatshamak dosha karma So In the present trial an attempt has been made to establish the efficacy of XX vaginal spray and XX Vaginal suppository in the management of acharna yoni vyapat w s r to vaginal microbiota dysbiosis