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CTRI Number  CTRI/2026/01/100678 [Registered on: 09/01/2026] Trial Registered Prospectively
Last Modified On: 28/12/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Other (Specify) [Trans-arterial micro embolization of posterior tibial artery in refractory plantar fasciitis.]  
Study Design  Single Arm Study 
Public Title of Study   Fixing Heel Pain: How a Simple, Low-Risk Treatment Can Help When Plantar Fasciitis Won’t Go Away 
Scientific Title of Study   Clinical Outcome of Transcatheter arterial microembolization in patients with refractory plantar fasciitis. 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Divyanshu Chauhan 
Designation  Post Graduate 
Affiliation  Vardhman Mahavir Medical College and Safdarajang Hospital 
Address  Department of Radiodiagnosis and IR, VMMC and Safdarjung Hospital, Ansari Nagar east, New Delhi- 110029

New Delhi
DELHI
110029
India 
Phone  8178500445  
Fax    
Email  divyanshuchauhan6@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Geetika Sindhwani 
Designation  Associate Professor 
Affiliation  Vardhman Mahavir Medical College and Safdarajang Hospital 
Address  Department of Radiodiagnosis and IR, VMMC and Safdarjung Hospital, Ansari Nagar east, New Delhi- 110029

New Delhi
DELHI
110029
India 
Phone  8980808841  
Fax    
Email  sindhwani.geetika@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Divyanshu Chauhan 
Designation  Post Graduate 
Affiliation  Vardhman Mahavir Medical College and Safdarajang Hospital 
Address  Department of Radiodiagnosis and IR, VMMC and Safdarjung Hospital, Ansari Nagar east, New Delhi- 110029

New Delhi
DELHI
110029
India 
Phone  8178500445  
Fax    
Email  divyanshuchauhan6@gmail.com  
 
Source of Monetary or Material Support  
VVardhman Mahavir Medical College and Safdarajang Hospital, New Delhi. 
 
Primary Sponsor  
Name  Vardhman Mahavir Medical College and Safdarajang Hospital.  
Address  Vardhman Mahavir Medical College & Safdarjung Hospital Ansari Nagar Ring Road New Delhi 110029 
Type of Sponsor  Government medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Divyanshu Chauhan  VMMC and Safdarjung Hospital  Room no.47 (DSA Room), New Emergency Building, Department of Radiodiagnosis, Vardhman Mahavir Medical College & Safdarjung Hospital, Ansari Nagar, Ring Road, New Delhi 110029
South West
DELHI 
8178500445

divyanshuchauhan6@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee, VMMC and Safdarjung Hospital  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M00-M99||Diseases of the musculoskeletal system and connective tissue,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  NIL  NIL 
Intervention  Trans-artereial Microembolization.  Trans-arterial micro-embolization of the arteries (posterior tibial artery) showing showing abnormal vascular blush post-digital subtraction angiography  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  80.00 Year(s)
Gender  Both 
Details  All participants with age more than 18 years with a clinical
diagnosis of chronic plantar fasciitis with no improvement or persistent symptoms on
conservative treatment.
 
 
ExclusionCriteria 
Details  Patients with severe vascular disease, active infection, or significant allergies to embolic
agents.
Patients who have recently received treatments that could interfere with TAME, such as
steroid injections, might be excluded unless a sufficient waiting period has passed.
Patients with severe comorbidities or poor overall health are excluded.
Known coagulopathy or recent trauma or surgery involving the affected limb.
Pregnancy & other contraindications to radiation exposure.
Inflammatory & Connective Tissue Activity 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Improvement in VAS score after the procedure and on follow up visits  Follow up assessment at 1 and 4 months post procedure. 
 
Secondary Outcome  
Outcome  TimePoints 
Plantar fascia thickness change in ultrasound pre-procedure and on follow up.  Follow up USG at 1 and 4 months post procedure. 
 
Target Sample Size   Total Sample Size="35"
Sample Size from India="35" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2/ Phase 3 
Date of First Enrollment (India)   27/01/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Plantar fasciitis is the most common cause of heel pain, traditionally considered an inflammatory condition. However, it is now better understood as a consequence of biomechanical stress and degenerative changes within the plantar fascia. The plantar fascia is a thick fibrous band that runs beneath the longitudinal arch, extending from the medial calcaneal tubercle to the plantar plates of the proximal phalanges.
Patients typically experience intense heel pain during their first steps in the morning, which tends to subside with daily activity. This condition affects both sedentary and physically active individuals, with a higher prevalence in females. While plantar fasciitis usually affects one foot, approximately 30% of patients report bilateral symptoms.

Standard Treatment: Initial treatment is primarily conservative and includes rest and NSAIDs to reduce discomfort, Orthoses such as heel pads, stretching exercises targeting the gastrocnemius and plantar fascia. If refractory to conservative treatment, then minimal invasive procedures can be done which includes injections including corticosteroids and botulinum toxin and adjunct therapies such as shockwave therapy, therapeutic ultrasound, and platelet-rich plasma (PRP) infusion.
Although most cases resolve within 6 months of standard therapy, a subset of patients continues to suffer from chronic pain and may be considered for surgical intervention. However, surgery is not always successful and can carry a risk of complications, including nerve injury, infection, and prolonged recovery.

Emerging Treatment: Transcatheter Arterial Micro- Embolization (TAME)
Chronic plantar fasciitis has been linked to increased vascularity in the affected fascial tissue. This increased blood flow may contribute to persistent pain through ongoing nociceptor stimulation and the release of inflammatory mediators. Transcatheter arterial micro-embolization (TAME) is a minimally invasive procedure that selectively occludes the abnormal neo-vessels supplying the plantar fascia. By cutting off this aberrant blood flow, the therapy aims to reduce inflammation and pain. Recent studies have shown that TAME is effective in treating chronic musculoskeletal conditions such as osteoarthritis, tendinopathy, and enthesopathy—including plantar fasciitis.
 
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