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CTRI Number  CTRI/2025/05/086940 [Registered on: 14/05/2025] Trial Registered Prospectively
Last Modified On: 08/05/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   The Utility of Individualised Homoeopathic Medicine in Cases of Hypersomnia. 
Scientific Title of Study   To Study Utility of Individualized Homeopathic Medicine In Cases Of Hypersomnia Using Homeopathic Medical Repertory By Dr. Robin Murphy 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Ripalkumar Gohil 
Designation  BHMS PG Scholar 
Affiliation  Jawaharlal Nehru Homoeopathic Medical College 
Address  Room No 401 A PG Department of Case taking And Repertory, Jawaharlal Nehru Homoeopathic Medical College, Parul University, P.O.Limda, Ta. Waghodia , Dis. Vadodara, Gujarat, 391760

Vadodara
GUJARAT
391760
India 
Phone  9624772392  
Fax    
Email  2304082030002@paruluniversity.ac.in  
 
Details of Contact Person
Scientific Query
 
Name  Dr Jignesh Patel 
Designation  Head Of Department ,Department Of Case Taking And Repertory 
Affiliation  Jawaharlal Nehru Homoeopathic Medical College 
Address  Room No 401 A Department of Case taking And Repertory, Jawaharlal Nehru Homoeopathic Medical College, Parul University, P.O.Limda, Ta. Waghodia , Dis. Vadodara, Gujarat, 391760

Vadodara
GUJARAT
391760
India 
Phone  9909949221  
Fax    
Email  jignesh.patel79013@paruluniversity.ac.in  
 
Details of Contact Person
Public Query
 
Name  Dr Jignesh Patel 
Designation  Head Of Department ,Department Of Case Taking And Repertory 
Affiliation  Jawaharlal Nehru Homoeopathic Medical College 
Address  Room No 401 A Department of Case taking And Repertory, Jawaharlal Nehru Homoeopathic Medical College, Parul University, P.O.Limda, Ta. Waghodia , Dis. Vadodara, Gujarat, 391760

Vadodara
GUJARAT
391760
India 
Phone  9909949221  
Fax    
Email  jignesh.patel79013@paruluniversity.ac.in  
 
Source of Monetary or Material Support  
Jawaharlal Nehru Homoeopathic Medical College, Parul University, P.O. Limda, Ta. Waghodia, Dist. Vadodara, Gujarat, India Pin Code 391760  
 
Primary Sponsor  
Name  Dr Ripalkumar Gohil 
Address  Jawaharlal Nehru Homoeopathic Medical College, Parul University, P.O. Limda, Ta. Waghodia, Dist. Vadodara, Gujarat, India, India Pin Code- 391760  
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Ripalkumar Gohil  Jawaharlal Nehru Homoeopathic Medical College And Hospital  OPD Room NO. 110, Jawaharlal Nehru Homoeopathic Medical College And Hospital, Parul University, P.O. Limda, Ta. Waghodia, Dis. Vadodara, Gujarat, 391760
Vadodara
GUJARAT 
9624772392

ripalgohil126@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Jawaharlal Nehru Homoeopathic Medical college( Institutional Ethics Committee For Human Research  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: G471||Hypersomnia,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  NIL  NIL 
Intervention  Individualized Homoeopathic Medicine  Individualized Homoeopathic Medicine in 30,200,1M Potency BD or TDS for 15 days for 3 month 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  1. Patients fulfilling the DSM 5 criteria Of Hypersomnia.
2. Pre Diagnosed Cases Of Hypersomnia.
3. Age Between 18 years to 70 years.
4. Both Male and Female Gender are Included.
5. All socio economic class Patients. 
 
ExclusionCriteria 
Details  1. Patients Who Does not give Consent.
2. Excessive Day time sleepiness Due to Insomnia.
3. Pregnant and Lactating Women.
4. Patient with Severe Systemic Disease.
 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
To study effectiveness of Individualised Homeopathic medicine selected in cases of
Hypersomnia using Homoeopathic medical repertory by Dr. Robin Murphy. 
3 Months 
 
Secondary Outcome  
Outcome  TimePoints 
To Assess the outcome in sleepiness using Epworth sleepiness scale after prescribing
individualized Homeopathic medicine. 
3 Months 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/06/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Hypersomnia is a sleep disorder marked by excessive daytime sleepiness (EDS), prolonged nighttime sleep, irresistible and refreshing sleep episodes, and difficulty waking up. It can significantly impair daytime alertness and overall quality of life. According to the ICD-11, it is classified under code 7A21. Surveys indicate that up to 25% of adults experience persistent daytime sleepiness, with moderate EDS affecting around 15% and severe EDS around 5% of the general population. In India, EDS prevalence ranges from 5–10% in the general population and up to 80% among working professionals like doctors, nurses, and IT workers.

Homeopathy, based on the principle of treating the individual rather than the disease, utilizes potentized remedies to stimulate the body’s vital force and restore homeostasis. In this context, individualized Homeopathic treatment offers potential in managing Hypersomnia effectively, similar to its application in other sleep disorders such as insomnia.

Dr. Robin Murphy’s Homeopathic Medical Repertory, which incorporates classical and clinical approaches including Kent’s generals and Boenninghausen’s methodology, offers more than 500 rubrics related to sleepiness. Its Constitution chapter aids in accurate remedy selection. Despite the significance of Hypersomnia and the comprehensive nature of Murphy’s repertory, no clinical studies in India have evaluated its application in managing Hypersomnia.

This study aims to assess the effectiveness of individualized Homeopathic remedies selected using Murphy’s Repertory in treating Hypersomnia. The Epworth Sleepiness Scale (ESS), a validated 8-item questionnaire, will be employed to assess sleepiness severity. The research seeks to bridge the gap in Indian literature on Homeopathic treatment of Hypersomnia and provide valuable clinical data. It is anticipated that individualized Homeopathic intervention will alleviate symptoms, improve quality of life, and reduce the burden of Hypersomnia in affected individuals.
 
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