India has one the highest incidences of Gallbladder Cancer (GBC) in the world, as per registry and GLOBOCAN data. Advanced GBC has a poor prognosis hence early diagnosis and management are crucial. Ultrasound/ Sonography is often the first imaging test to evaluate patients with suspected gallbladder diseases. Gallbladder wall thickening (GWT) is a common finding at ultrasound. It is nonspecific and represents both benign and malignant diseases.

The importance of wall thickening as a sign of gallbladder cancer is often missed during preoperative evaluations. This can lead to finding gallbladder cancer by chance or, worse, to more advanced disease and poorer outcomes. This study looks at past data to find out how well the GB-RADS scoring system works in identifying whether gallbladder conditions are malignant or benign.

The Gall Bladder Reporting and Data System (GBRADS) is ultrasound risk stratification reporting tool proposed to improve consistency in ultrasound interpretations, reporting and assessment of risk of malignancy in gallbladder wall thickening.

In this study we will evaluate the correlation between the GBRADS ultrasound scoring system and histopathological findings in order to determine the accuracy of GBRADS scores in predicting malignancy and benign conditions of gall bladder.

In this study we will enroll any patients with suspected gallbladder pathology who have undergone ultrasound imaging followed by histopathological examination (either a biopsy or a surgery) only patients with metastatic disease at presentation will be excluded.

A total pf 150 participants will be collected in this study. This is a retrospective study only data collection will be done. In this study patients underwent ultrasound and scored via GBRADS for any suspected gall bladder pathology and histopathological examination from 1st of February 2023 will be enrolled into the study.