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CTRI Number  CTRI/2025/05/086431 [Registered on: 06/05/2025] Trial Registered Prospectively
Last Modified On: 05/05/2025
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   How Active Release Technique Improves Hamstring Flexibility and Glute Muscle Strength 
Scientific Title of Study   Analysis of Active Release Tecnique (ART) and Active Knee Extension (AKE) Exercise on Hamstring Flexibility and Gluteus Maximus Endurance in Young Adults  
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Subhashchandra Rai 
Designation  Principal and Professor 
Affiliation  Tejasvini Physiotherapy College 
Address  Tejasvini Physiotherapy College Kudupu Mangalore Karnataka India 575028

Dakshina Kannada
KARNATAKA
575028
India 
Phone  9448158751  
Fax    
Email  physio.subhashrai@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Subhashchandra Rai 
Designation  Principal and Professor 
Affiliation  Tejasvini Physiotherapy College 
Address  Tejasvini Physiotherapy College Kudupu Mangalore Karnataka India 575028


KARNATAKA
575028
India 
Phone  9448158751  
Fax    
Email  physio.subhashrai@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Subhashchandra Rai 
Designation  Principal and Professor 
Affiliation  Tejasvini Physiotherapy College 
Address  Tejasvini Physiotherapy College Kudupu Mangalore Karnataka India 575028


KARNATAKA
575028
India 
Phone  9448158751  
Fax    
Email  physio.subhashrai@gmail.com  
 
Source of Monetary or Material Support  
Tejasvini Physiotherapy College Kudupu Mangalore karnataka 575028 
 
Primary Sponsor  
Name  Tejasvini Physiotherapy College 
Address  Tejasvini Physiotherapy College Kudupu Mangalore Karnataka India 575028 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Subhashchandra Rai  Tejasvini Physiotherapy College  Physiotherapy Department Tejasvini Physiotherapy College Kudupu Mangalore Karnataka India 575028
Dakshina Kannada
KARNATAKA 
9448158751

physio.subhashrai@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Ethical Clearane Committee, IGTAMSU  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Hamstring Tightness 
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Active Knee Extension Exercises  Active Knee Extension Exercises for the Hamstring fexibility Dose: 3-5 repeitions of Active knee extensions Route: Active Exercises (10 Reps) Total Duration: 5-10 Min 
Intervention  Active Release Technique  Active Release Technique of Hamstring Muscles Dose: 3 release of 2-3 min in each sets Route: Hands-on technique Total Duration: 5-10 Min 
 
Inclusion Criteria  
Age From  20.00 Year(s)
Age To  35.00 Year(s)
Gender  Both 
Details  Healthy Individuals
Hamstring Tightness Bilateral or unilateral
Recreational Athletes 
 
ExclusionCriteria 
Details  Any injury in the Hamstring Muscles
Actively training individuals
Professional Atheletes 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Not Applicable 
Blinding/Masking   Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Acktive Knee Extension Range  Pre and Post 
 
Secondary Outcome  
Outcome  TimePoints 
Single Leg ip Extension Isometric Hold  Pre and Post 
Pelvic Inclination Angle  Pre and Post 
Hip and Knee Range of Motions  Pre and Post 
 
Target Sample Size   Total Sample Size="200"
Sample Size from India="200" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 1 
Date of First Enrollment (India)   01/06/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
In order to improve posture and any joint pain or injury, flexibility of the hamstrings is essential. We’re assuming that this movement will require the flexibility of our hamstrings. That doesn’t make sense. The hamstrings don’t take care of folding the body forward, they make sure that we can stand up. As a result, both above and below the muscle group, they affect the spine and all of the joints. 
The hamstrings are tendinous tissues, according to their design. It means they’re dense and strong, which allows them to be easily accumulated with unhealthy fascia. They’re attached to the pelvis, their health and flexibility determines how they move. The hamstrings cease to move as soon as they are full of dense, scarified fascia. In each hamstring, there may be the option of freezing them in their shortest position, longest posture, twisted or combined positions. Malfunctioned hamstrings hold the pelvis in a twisted position. Inturn, it creates weak alignment to the hip and knee joints, compression on the back of the spinal column, and tight posture in the shoulders and neck. The foundation of having a body which moves and feels better head to toe is an increase in hamstrings flexibility and pelvis movement. During most forms of traditional hamstring stretching three things happen: micro tears form in the muscle, training muscle to stay over-stretched and weak, and finally overstretching ligaments and tendons around the joints.
Sitting is a greater threat to public health than cigarettes. Over half their day is spent sitting, according to the average person. And every single day, the average office worker is sitting for an astonishing 15 hours. The risk of
premature death is also increased as your sitting time increases. To create thick fascia in your hamstring muscles it takes 20 minutes to sit, so this area is where we recommend different types of stretching for strengthening the
leg’s flexibility. We’re sitting here for many hours a day, looking at our young age. Hamstrings are getting torn in the form of small micro tears all over muscles while sitting. It feels like they are repeating themselves in a repetitive way and getting small tears. Body’s immune system patches up the injury/tears with the only bandaid it has: dense fascia. So, when standing up, hamstrings don’t stretch as easily and they have a tendency to slow down the flow of motion in pelvis. This is causing chaos in entire body, ankles, knees, hips, spine, shoulders, neck, elbows and even wrists.
Glutes and hamstrings; the most frequently used, untrained muscles in the body. These two strong muscles are used in practically all the movements you could imagine, like walking, standing, lifting and jumping. In order to stabilize the body, prevent falls, and even bend and stretch, the glutes and hamstrings are active. The movements of hip and knees are controlled by the hamstrings. They can move hips forward and backwards while work together as a group. They’re also helping with the rotation of legs. The hamstrings allow to maintain stability and balance, while holding up but not moving. Compared to this, gluteal muscles are able to control a variety of movements including extensions, abductions and internal or external rotation of hip joints. In addition, the gluteus maximus plays a major role in knee extension.
In a great number of movements these muscles support the body, but are very weak and frequently undertrained. During the days of our ancestors, when they walked without shoes, their gluteal muscles had been very powerful and activated during movement to enable them to stay seated in a latrine squat for meals or conversation while being able to use an equivalent toilet. Today’s majority of people are doing swayback postures that minimize the activation of glutes, which has resulted in a massive lack of development of muscle strength.
Active release techniques are a soft tissue technique that works by reducing muscle tension through the removal of fibrosis and adhesions, which may develop in tissues as a result of overloading due to repeated use. Muscle
weakness, numbness, pain, tingling, and burning sensation may occur as a result of these disorders. ART has been reported to be both a diagnostic and a treatment technique, however, there is little scientific evidence regarding the effects of ART on various pathologies, with most of the available evidence being anecdotal and based on case reports. ART was developed and patented by Dr. P. Michael Leahy, DC, CCSP, a Doctor of Chiropractic medicine. Dr. Leahy’s observation that patient symptoms had been associated with changes in their soft tissues has led him to invent a technique which is entirely focused on the symptom of the patient. In 1985 he published his first works under the name of Myofascial Release and patented them later as Active Release Techniques.
Due to trauma, such as swelling, fibrosis and adhesions, tissues may develop negative changes. During treatment, the clinician uses manual therapy to apply compressive, tensile, and shear forces to address repetitive strain
injuries, cumulative trauma injuries, and constant pressure tension lesions. While the patient is being instructed to move the injury site out of its shortened position and into a longer position, the clinician applies deep tension in the area of tenderness. The placing of a contact point near the lesion causes the patient to move in a manner that produces a longitudinal sliding motion of soft tissues, e.g., nerves, ligaments, and muscles beneath the contact point.
The ART system is useful for active people at every level. In order to ensure that patients have the means of improving their sporting performance, it may enable them to identify and eliminate limits limiting their ability to perform a
given activity. This typically occurs after a biomechanical analysis of patients’ movements was carried out by the practitioner.
ART Performance Care should be administered after a trauma based injury has been healed. ART Performance Care is focused on removing restriction that impairs the full range of motion, enabling affected soft tissues to be fully
responsive and performing at its best. This process is likely to have a significant effect on sports performance in terms of power, strength and flexibility. So the aim of current study is to evaluate the effectiveness of ART over
active knee extension on improving hamstring flexibility and gluteus maximus endurance in young adults.
 
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