The dissertation titled Assessment of Behavioural Changes in Children with Autism Spectrum Disorder Using Individualised Homoeopathic Medicine: A Single Arm Study aims to evaluate the effectiveness of individualized homoeopathic treatment in managing behavioural symptoms in children with Autism Spectrum Disorder (ASD). Autism is a neurodevelopmental disorder marked by impairments in social interaction, communication, and repetitive behaviours, with a rising global prevalence. Although conventional treatments are available, they often come with limitations such as high cost, limited accessibility, and potential side effects. Homoeopathy, particularly in its individualized form, offers a potential alternative, but lacks strong scientific backing due to methodological inconsistencies in existing studies. This study addresses this gap by conducting a one-year interventional single-arm study involving 34 children aged 3 to 15 years, diagnosed with ASD using the Indian Scale for Assessment of Autism (ISAA) and ICD-10 criteria. The homoeopathic medicines are selected through classical case-taking and repertorisation methods. Behavioural outcomes are measured using pre- and post-treatment ISAA scores. The study hypothesizes that individualized homoeopathic medicine can significantly improve behavioural symptoms in children with ASD. Statistical analysis will be conducted to determine the effectiveness of the intervention. This research seeks to contribute to the growing evidence base on alternative therapies for ASD and promote a more integrative approach in paediatric health care.