1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response (Others) -  All the data to be provided when needed through email iswaryah01@gmail.com


6. For how long will this data be available start date provided 01-01-2028 and end date provided 01-01-2033?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

·       Recurrent cystitis is a prevalent urological condition, particularly in postmenopausal women, affecting their quality of life, daily activities, and mental well-being. Recurrent lower urinary tract infections are common after the menopause and occur in more than 10 percentage of women over the age of 60. Due to estrogen deficiency there is rise in vaginal pH promotes an alteration in the normal vaginal flora, with decreased lactobacilli leading to increased colonization by pathogenic faecal flora. This increases the incidence of urinary tract infections in postmenopausal women. Recurrent UTI refers to a group of patients who have suffered from a UTI at least three times in the last 12 months or at least two times during the previous 6 months and have diminished quality of life. The purpose of this study is to do a systematic clinical evaluation of Sepia officinalis in the treatment of recurrent cystitis in postmenopausal women. The validated Acute Cystitis Symptom Score will be used as an evaluation assessment tool to measure the degree of improvement and symptom severity after homoeopathic treatment. The objective of my study is to assess whether individualized Sepia officinalis therapy can effectively reduce the frequency and severity of recurrent cystitis episodes, and to evaluate improvement using a validated symptom-based scale. A minimum of 30 postmenopausal women with recurrent cystitis will be selected from OPD, IPD, and peripheral centers of White Memorial Homoeopathic Medical College and Hospital. Detailed case records as per the approved format will be maintained, and diagnosis will be confirmed using clinical history and the Acute Cystitis Symptom Score supported by clinical examination and urine tests when needed. Sepia officinalis will be prescribed and patients will be followed weekly during acute episodes, then every two weeks or as required for six months. Improvement will be assessed by comparing pre and post treatment ACSS scores. The effectiveness of the Homoeopathic medicine Sepia officinalis will be evaluated based on the percentage reduction in the Acute Cystitis Symptom Score from pre-treatment to post treatment.