Patients with external fixator applied, with infected pin tract will be participating in this study in which after fulfilling the inclusion criteria patients will undergo a history and physical examination by clinicians. Patients will be allotted one of the two groups according to the grade of infection (Grade-1 not responding to treatment and Grade-2). 

If patient has grade-1 pin tract infections they will be subjected to 1 week of daily dressing with povidone iodine as per standard treatment guidelines, if the infection is not responding to treatment, patient will be recruited in the study. Randomization will be done into two groups (Group S and Group PRF). If patient is in the Group PRF then they will receive iPRF and/or PRF gel injection after curettage, if patient is  in Group S they will receive standard treatment. While all grade 2 pin site infections will be subjected to randomization in to two groups. Group S will receive standard treatment with antibiotics and those in group PRF will be managed by removal of any crust or any discharge followed by liquid PRF infiltration around the infected pin site. The pin site will be reassessed after 3-5 days and if required, another injection of liquid PRF will be injected. If there is worsening, rescue oral antibiotics will be started. Patients are not allowed to request for change of group during the study. Around 10-20 ml of blood will be taken from the patient which might cause some discomfort due to needle prick and which will be used to make platelet rich fibrin using a centrifuge, This PRF will be injected to infected pin tract in the study group. Patient will be assessed post-injection clinically using Visual analogue scale. If the patient is willing to participate in the study then they have to undergo a follow up of at least 3-7 days. At each follow up patient will be assessed clinically using VAS.