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Intervention / Comparator Agent
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| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Drug | Classical | | (1) Medicine Name: Rajavrukshadipachana Kashaya., Reference: Bharat Bhaishajya Ratnakara, Shloka no.:-5863, Route: Oral, Dosage Form: Kwatha/ Kashaya, Dose: 25(ml), Frequency: bd, Bhaishajya Kal: Pragbhakta, Duration: 15 Days, anupAna/sahapAna: Yes(details: -ushna jala), Additional Information: - | | 2 | Intervention Arm | Drug | Classical | | (1) Medicine Name: Kandwado Lepa, Reference: Sharangadhara Samhita: Lepa prakarana , chapter -11, shloka no.-50 , Route: Topical, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: bd, Bhaishajya Kal: Adhobhakta, Duration: 15 Days, anupAna/sahapAna: Yes(details: -Jala), Additional Information: - | | 3 | Comparator Arm | Drug | Classical | | (1) Medicine Name: Kasamardai Lepa , Reference: Bharat Bhaishajya Ratnakara, Shloka no - 1412, Route: Topical, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: bd, Bhaishajya Kal: Adhobhakta, Duration: 15 Days, anupAna/sahapAna: Yes(details: Jambira swarasa), Additional Information: - | | 4 | Comparator Arm | Drug | Classical | | (1) Medicine Name: Navakashaya , Reference: Chakradatta: Chikitsa sthana : Kushta Chikitsa Adhyaya :shloka no.-75 , Route: Oral, Dosage Form: Kwatha/ Kashaya, Dose: 25(ml), Frequency: bd, Bhaishajya Kal: Pragbhakta, Duration: 15 Days, anupAna/sahapAna: Yes(details: -ushna jala ), Additional Information: - |
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Brief Summary
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Ayurveda says "Sarvamanya Parityajya Shariramarupalayer" which means health should be maintained by leaving other materials aside. If health is not maintained properly one cannot lead a happy life.
In Ayurveda the word Twacha is derived from "Twacha Samvarne Dhatu" which means covering of body Skin is the largest organ of integumentary system, it covers an area of 1.8 square meters and serves as a protective barrier that prevent internal tissues from exposure to trauma, ultra violet radiation, temperature,toxins, etc.
Ayurveda explains Twacha is one among the Panchagnanendriya attributed with the function of sensationof touch, it is the Ashraya Sthana of Sweda and Loma, hence skin maintains the temperature regulation, electrolyte balance and hydration of skin. Since Twacha is Upadhatu of Mamsadhatu its role is to do Dharana (carrying).
Shabdakalpadruma says "Twachati Samvrunoti Medoshonita Kamiti" which means Twacha covers the underlying Rakta, Mamsa, Medodharu. Hence one of the important function of skin is to act as a strong physical barrier against microbial invasion and protect the body against mechanical, thermal, chemical, osmotic and photo damage.
There are many triggering factors like, changing lifestyle, pollution, excessive stress, irritants, allergens and use of chemical products, people are suffering from variety of skin diseases which is described under the term of Kushta Rogas, Which can cause significant impact on person’s quality of life.
The word "Kushta" means, that it comes out from the inner part to the outer part of skin and destroyes the organs of the body. Acharya Charaka has emphasized that Kushta is one among the Ashtamahagada.
According to Acharya Charaka, Kushta is divided into two categories Mahakustha(7), and Kshudra Kuatha(11). Vicharchika is one among the Kshudra Kustha, Vicharchika is Rakta Pradoshaja Vyadhi involvement of three Doshas with the predominance of Kapha Dosha
The Charaka Samhita describes Vicharchika as a skin condition, charecterised by Kandu (itching), Pidaka(popular eruption), Shyavata(black reddish discoloration) and Bahusrava(discharge). According to Shabdakalpodruma the disease which coats the skin in particular manner and causes cracking of skin of hands and feet mainly,
Though, there is no specific description about Nidana of Vicharchika but it being a type of Kshudra Kushta, the Nidana of Kushta considered as Nidana of the Vicharchika those are Viruddha Ahara, Drava, Snigdha, Guru Ahara, Panchakarma Apachara, Diwaswapna and Papakarma etc. Viruddha Aharas like Matsya and Payasa, Madhu and Sarpi, Madhu and Ushnajala, Ksheera and Lavana, Sheetajalasevana after Snehapana etc. leads to Vicharchika,
Though, there is no specific description about samprapti of Vicharchika but it being a type of Kshudra Kushta, the samprapti of Kushta considered as samprapti of the Vicharchika, such as due to the Nidana Sevana, the vitiation of Tridoshas occurs, then it produces Dhatu Shaitilyata leading to the Dooshona of Twak, Rakta, Mamsa, Lasika(ie Sapta Dravya) thus the manifestation of Vicharchika takes place
Vicharchika can be co-related to eczema, which is a form of dermatitis or chronic inflammatory condition of the skin, characterised by an itchy, reddish, gross thickening of skin (lichenification). Other features such as scaling, cracking, and swelling of the skin occures.
The reported prevalence ranged from 3.1% to 7.2% among the pediatric population upto 16 years of age. The prevalence of eczema ranged from 0.98% to 9.2%, in studies including pediatric and adult patients.
Eczema is considered as major health problem, affecting a high proportion of the population in India. Increased consciousness especially among the youth, because of their extra cautious towards the skin care, it may leads to an anxiety and affect socioeconomic status of an individual, so there is need of efforts to minimize the skin disease. Eczema can cause a heavy emotional damage and psychological distress, these could be a burden to the patient and that may be far worse than the physical impact.
Raktadushti is the main cause of Vicharchika and Shodhana Karma helps to eliminate vitiated Doshas from its root", but people are not ready to take because of their busy schedules, work pressures and meetings etc.
Hence, an effort has been made to check the efficacy of Shamana Chikitsa in the management of Vicharchika through the present research work.
Hereby an effort shall be made to evaluate the therapeutic efficacy of interventions such as Shamana Chikitsa with Kandwado Lepa, Rajavrukshadipachana Kashaya and Kasamardadi Lepa, Navakashaya in the management of Vicharchika.
Ingredients of Kandwado Lepa are Chakramarda, Bakuchi, Sarshapa, Tila, Kushta, Haridra, Daruharidra and Musta, having a Guna of Kandugna, Kushtagna and Raktaprasadana.
Ingredients of Rajavrukshadipachana Kashaya are Rajavruksha, Ashwatha, Amruta, Nimba, Haritaki, Vasa, Khadira, Manjistha and Kanthakari, having a Guna of Tridoshahara, Kushtagna and Kandugna.
Ingredients of Kasamardai Lepa are Kasamarda and Jambira swarasa having a Guna of Kushtagna, and Kaphavatagna.
The ingredients of Navakashaya are Triphala, Patola, Rajani, Manjishta, Rohini, Vacha and Nimba, having a Guna of kapha pitta prasamana, raktaprasadaka, and kushtagna properties.
The aim of this study is to conduct a research on Vicharchika with the new Ayurvedic formulation which have not yet been explored, that could be easily available and affordable to the people. |