1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   Response -  Analytic Code
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - Any purpose.
   


5. By what mechanism will data be made available?
   Response (Others) -  data available on contacting the principal investigator Dr David k david.k@manipal.edu


6. For how long will this data be available start date provided 01-12-2026 and end date provided 01-01-2035?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Maintenance of high levels of oral hygiene plays a crucial role in success of any oral surgical procedure (1). Reduction of biofilm formation, prevention of infective complications on wound site and wound stability are very important for early wound healing (2). Reduction or elimination of oral biofilms is necessary to restore gingival tissues to a healthy state especially after a surgical procedure (3). However, mechanical means are often inadequate in ensuring plaque control and preventing infection at surgical sites (2,3). So, chemical agents can be used along with mechanical plaque control methods to ensure early wound healing (2).

Chlorhexidine is a widely used chemical antiplaque agent routinely prescribed to patients after common oral surgical procedures (1)(3)(4). It is a cationic bisbiguanide and has broad spectrum antimicrobial activity against gram positive bacteria, gram negative bacteria, yeast, viruses leading to chlorhexidine being a gold standard for oral biofilm prevention (3)(4).

 When Chlorhexidine mouthwash is taken over a prolonged period of time, it causes tooth discoloration, mucosal irritation, cytotoxicity, and taste alteration. Octenidine dihydrochloride (OCT), cationic surfactant molecule with antibacterial properties. It binds to negatively charged microbial surfaces and adheres tenaciously to lipid components, which breaks the cell membrane of yeast, bacteria, and fungi.

There are reports of its drawback, including its unpleasant bitter taste; nonetheless, many manufacturers address this issue by adding flavourings before introducing it to the market.. With fewer reported adverse effects of octenidine hydrochloride, it may be used for a longer time than chlorhexidine.

Therefore, this study aims to compare the efficacy of two mouthwashes— .1% Octanidine and .12% Chlorhexidine based mouthwashes as an adjunctive post periodontal flap surgery.