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CTRI Number  CTRI/2025/11/097922 [Registered on: 24/11/2025] Trial Registered Prospectively
Last Modified On: 23/11/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group, Active Controlled Trial 
Public Title of Study   Simple Exercises for Better Neck Health and Hand Power for cervical radiculopathy  
Scientific Title of Study   Integrating Neuromobilization versus Stabilization Exercise to improve Pain, Disability, Health related quality of life, and hand strength among Cervical Radiculopathy.  
Trial Acronym  RCT 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Surbhi Kaura  
Designation  Associate Professor 
Affiliation  Galgotias University 
Address  Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201

Gautam Buddha Nagar
UTTAR PRADESH
203201
India 
Phone  8527389589  
Fax    
Email  surbhi.kaura@galgotiasuniversity.edu.in  
 
Details of Contact Person
Scientific Query
 
Name  Surbhi Kaura  
Designation  Associate Professor 
Affiliation  Galgotias University 
Address  Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201


UTTAR PRADESH
203201
India 
Phone  8527389589  
Fax    
Email  surbhi.kaura@galgotiasuniversity.edu.in  
 
Details of Contact Person
Public Query
 
Name  Chhavi Aggarwal 
Designation  Student 
Affiliation  Galgotias University 
Address  Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201

Gautam Buddha Nagar
UTTAR PRADESH
203201
India 
Phone  9511575012  
Fax    
Email  chhavi.24smas2060005@galgotiasuniversity.ac.in  
 
Source of Monetary or Material Support  
nil  
 
Primary Sponsor  
Name  Galgotias University  
Address  Block B 3rd floor Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201 
Type of Sponsor  Research institution 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Alok Prabhat  SS HOSPITAL   f -2, 6R56+CJM, Bhagat Singh Colony, U.I.T., Bhiwadi, Rajasthan 301019 Department of physiotherapy (basement )
Alwar
RAJASTHAN 
9608927223

physioalokmishra19@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Departmental Research committee Galgotias university  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M00-M99||Diseases of the musculoskeletal system and connective tissue,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  cervical stabilization exercises   cervical flexion and extension dynamic isometric exercise in sitting position, bicep curls, bench press,Neck isometric Stretching -levator scapulae , scalene Hand exercise (hand putty squeezed in one hand , rolling putty b/w both hands)  
Intervention  neruomobilization   Neuro mobilization ( sliding of median nerve, Neck isometric Stretching -levator scapulae, scalene Hand exercise (hand putty squeezed in one hand, rolling putty b/w both hands)  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  50.00 Year(s)
Gender  Both 
Details  1.Participants aged between 18 to 50 years.
2.Limited ROM with neck pain.
3.Diagnosed by physician (MRI,CT SCAN )

 
 
ExclusionCriteria 
Details  1. Congenital Cervical
2. Autoimmune neuromuscular disorder
3. Vertigo, Dizziness or Nausea
4. Cervical Artery Dysfunction
5. Osteoporosis
6. Traumatic history
7. Epilepsy
8. Any cardiac or malignancy history
 
 
Method of Generating Random Sequence   Stratified randomization 
Method of Concealment   Other 
Blinding/Masking   Participant and Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Pain by Visual Analog Scale
Disability by Neck disability index 
Baseline and 4 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
1.Hand Strength by hand-held dynamometer
2.HrQOL by SF 36


 
baseline and 4 weeks  
 
Target Sample Size   Total Sample Size="64"
Sample Size from India="64" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   25/12/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  25/12/2025 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="8"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

The study aims to evaluate the effectiveness of neuromobilization and cervical stabilization exercises in improving pain, disability, hand strength, and health-related quality of life (HrQOL) in patients with cervical radiculopathy.

Phase 1: Screening and Consent. Participants will be briefed on the study and screened based on inclusion/exclusion criteria. Informed consent will be obtained.

Phase 2: Assessment.  Pain (VAS)and disability(NDI); Hand grip strength by hand dynamometer of both the groups.

A total of “N=64” subjects will be enrolled in the study and randomly assigned into Group A and Group B 

Group A Neuromobilization with manual therapy
This group employs a neural mobilization approach, involving median nerve sliding, with one set of five repetitions, each held for five seconds. Using the method by David Butler, which states that the individual was in supine position with the shoulder in lateral rotation and abduction, with the elbow in extension, forearm in supination, wrist, finger, and thumb in extension, and contralateral side in flexion and shoulder in abduction for stretch.
Some additional exercises, like Neck isometric, with two sets of five repetitions, each hold for five seconds, stretching of muscles like levator scapulae, scalene, with five repetitions in two sets, each holding for five seconds
With hand exercises for tingling and numbness in the arm, exercises like hand putty squeezing, and rolling putty between both hands.

 

Group B Cervical Stabilization with  Manual Therapy

cervical flexion and extension dynamic isometric exercise in sitting position, bicep curls, bench press, 5 repetitions each in two sets, each holding for five seconds 

additional exercises, like Neck isometric, with two sets of five repetitions, each hold for five seconds, stretching of muscles like levator scapulae, scalene, with five repetitions in two sets, each holding for five seconds

With hand exercises for tingling and numbness in the arm, exercises like hand putty squeezing, and rolling putty between both hands.

All outcome measures will be measured at baseline and the 4th week of the trial. Both groups received the sessions three times a week for 4 weeks. The data will be analyzed to evaluate the best  therapeutic option for cervical radiculopathy.

 
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