1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Researchers who provide a methodologically sound proposal.
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [maheshkhk99@gmail.com].
   


6. For how long will this data be available start date provided 27-07-2025 and end date provided 27-07-2028?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - nil

Study Design and Methodology

Participants
Adult patients aged 18 to 65 years undergoing elective surgery under general anaesthesia requiring endotracheal intubation will be enrolled provided they meet the inclusion criteria Informed written consent will be obtained from all participants prior to enrolment

Randomization
Patients will be randomly allocated into two groups using a computer generated randomisation table

• Group V Video Laryngoscope Group

• Group C Conventional Laryngoscope Group

Preoperative Assessment
All patients will undergo a thorough airway examination including

• Mallampati grading

• Mouth opening

• Thyromental distance

• Neck circumference

Relevant clinical history will also be recorded Standard preoperative fasting guidelines and ASA monitoring protocols will be followed

Anaesthetic Management
A standardized general anaesthesia protocol will be followed for both groups Monitoring will include

• Electrocardiography ECG

• Heart Rate HR

• Oxygen Saturation SpO2

• Non Invasive Blood Pressure NIBP cycled every 1 minute for 5 minutes post laryngoscopy and intubation

Baseline Parameters
Baseline values of Systolic Blood Pressure SBP Diastolic Blood Pressure DBP Mean Arterial Pressure MAP HR and SpO2 will be recorded

Induction Protocol

• Injection Fentanyl 15 mcg per kg IV

• Injection Propofol 1 to 2 mg per kg IV titrated to loss of verbal response

• After confirming adequate ventilation Injection Vecuronium 01 mg per kg IV will be administered

• Patients will be ventilated for 3 minutes with 100 percent oxygen and Sevoflurane 2 to 3 percent to achieve a MAC of 08 to 10

Airway Management
Cervical spine immobilization will be performed using manual inline stabilization MILS to prevent neck movement Patients will then be intubated using

• Group V Video laryngoscope

• Group C Conventional laryngoscope with an appropriate blade size

All intubations will be performed by experienced anaesthesiologists not residents The number of attempts for successful intubation will be recorded

Outcome Measures

Primary Outcome

• Time to successful intubation from laryngoscope insertion to confirmation by five point auscultation or appearance of ETCO2 trace

Unsuccessful intubations will be recorded as failures for the respective group and these patients will be excluded from hemodynamic data analysis

Use of adjuncts such as stylet bougie and BURP manoeuvre will be documented

Secondary Outcomes
Hemodynamic parameters including HR SBP DBP and MAP will be recorded noninvasively at 1 3 and 5 minutes post laryngoscopy

Severe stress responses requiring pharmacological intervention will be noted

Adverse events such as

• Desaturation SpO2 less than 93 percent

• Failed or oesophageal intubation

• Injuries to lips tongue teeth or oral cavity

• Any other complications

will be recorded

Both groups will proceed with standard general anaesthesia protocols post intubation