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CTRI Number  CTRI/2025/08/092763 [Registered on: 11/08/2025] Trial Registered Prospectively
Last Modified On: 08/08/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Other 
Public Title of Study   A Study Comparing Two Types of Physiotherapy Mulligan and Neural Mobilization Treatments to Improve Pain, Functionality and Joint position Sense for Patients with Neck Pain and Nerve Problems. 
Scientific Title of Study   Effectiveness of Spinal Mobilization with Arm Movement versus Neural Slider Technique on Pain, Functionality, and Joint Position Sense in Cervical Spondylosis with Radiculopathy: A Comparative Study. 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Yash Khairekar 
Designation  PG Student 
Affiliation  SPB Physiotherapy college surat  
Address  SPB Physiotherapy College OPD Ugat Bhesan Road Morabhagal Surat

Surat
GUJARAT
395009
India 
Phone  6351322526  
Fax    
Email  yashkhairekar50@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Neeti Mishra  
Designation  Professor  
Affiliation  SPB Physiotherapy College Surat 
Address  SPB Physiotherapy College OPD Ugat Bhesan Road Morabhagal Surat

Surat
GUJARAT
395005
India 
Phone  9879697384  
Fax    
Email  dr.neetimishra@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Neeti Mishra  
Designation  Professor  
Affiliation  SPB Physiotherapy College Surat 
Address  SPB Physiotherapy College OPD Ugat Bhesan Road Morabhagal Surat

Surat
GUJARAT
395005
India 
Phone  9879697384  
Fax    
Email  dr.neetimishra@gmail.com  
 
Source of Monetary or Material Support  
SPB Physiotherapy College OPD Ugat Bhesan Road Morabhagal Surat Gujarat India 395005 
 
Primary Sponsor  
Name  Yash Khairekar 
Address  SPB Physiotherapy College OPD Ugat Bhesan Road Morabhagal Surat Gujarat India 395005 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Yash Khairekar  SPB Physiotherapy College   SPB Physiotherapy College OPD (Musculoskeletal Department) Ugat Bhesan Road Morabhagal Surat
Surat
GUJARAT 
6351322526

yashkhairekar50@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee SPB Physiotherapy College  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M472||Other spondylosis with radiculopathy,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Neural Slider Technique with Conventional Treatent  The Neural Slider Technique, also known as nerve gliding or Neurodynamic sliding, is a gentle Neurodynamic intervention used in physiotherapy to treat patients with Cervical Spondylosis with Radiculopathy improve the mobility of peripheral nerves by promoting a sliding motion between the nerve and its surrounding tissues—without putting significant tension on the nerve. Conventional treatment for neck and upper back dysfunction often includes a combination of chin tuck exercises, active neck movements, neck isometrics, shoulder bracing, and trapezius self-stretching. This approach focuses on improving posture, reducing muscle tension, and enhancing strength and flexibility. Chin tucks help in correcting forward head posture by strengthening deep neck flexors, while active neck movements promote mobility and reduce stiffness. Neck isometrics involve static muscle contractions to build strength without joint movement, ideal for early rehabilitation. Shoulder bracing supports proper shoulder alignment and reduces strain on neck muscles. Lastly, trapezius self-stretching targets tight upper trapezius muscles, relieving tension and improving range of motion. Duration of Intervention is 15min, 4 Days per Week for 4 Week. 
Comparator Agent  Spinal Mobilization with Arm Movement and Neural Slider Technique  We need to compare Spinal Mobilization with Arm Movement (SMWAM) and the Neural Slider Technique to determine which is more effective in improving range of motion and reducing disability. SMWAM combines spinal joint mobilization with arm movement to enhance joint mobility and indirectly relieve neural symptoms, requiring therapist skill. The Neural Slider Technique, on the other hand, gently glides nerves through surrounding tissues to reduce nerve tension and directly improves neural mobility. Comparing these two will help identify which approach better improves range of motion and decreases disability in patients with Cervical Spondylosis with Radiculopathy. Total Duration of Each groups treatment is 15 mins 
Intervention  Spinal Mobilization with Arm Movement with Conventional Treatment  Spinal Mobilization with Arm Movement – Lateral Glide is a manual therapy technique commonly applied in the cervical spine, typically used to treat patients with neck pain, Cervical Spondylosis with Radiculopathy, or Neck dysfunction. It combines a sustained lateral glide mobilization of the spine with active arm movement by the patient. Conventional treatment for neck and upper back dysfunction often includes a combination of chin tuck exercises, active neck movements, neck isometrics, shoulder bracing, and trapezius self-stretching. This approach focuses on improving posture, reducing muscle tension, and enhancing strength and flexibility. Chin tucks help in correcting forward head posture by strengthening deep neck flexors, while active neck movements promote mobility and reduce stiffness. Neck isometrics involve static muscle contractions to build strength without joint movement, ideal for early rehabilitation. Shoulder bracing supports proper shoulder alignment and reduces strain on neck muscles. Lastly, trapezius self-stretching targets tight upper trapezius muscles, relieving tension and improving range of motion. Duration of Intervention is 15min, 4 Days per Week for 4 Week. 
 
Inclusion Criteria  
Age From  35.00 Year(s)
Age To  50.00 Year(s)
Gender  Both 
Details  Patients with Cervical Spondylosis with Radiculopathy, Symptoms at least from more than 3 months,
Patients diagnosed or referred patients of Cervical Spondylosis with Radiculopathy, Diagnosed by using Neuropathic Pain Diagnostic Questionnaire, Upper Limb Neurodynamic Test (Median Nerve and Ulnar Nerve), Spurling test, distraction test, neurodynamics tests, ipsilateral cervical rotation is less than 60 degree. (wainner’s cluster)
 
 
ExclusionCriteria 
Details  Patient having cervical PIVD, Myelopathy, Stenosis, Carcinoma, Etc, Patients with Cervicogenic headache, Patients who have history of any traumatic brain injury, whiplash injury and cervical spine surgery, Patients with fibromyalgia and other musculoskeletal disorders such as Ankylosing Spondylitis, Rheumatoid Arthritis, Patients with any deformity e.g. spasmodic torticollis, Sprengel’s deformity, scoliosis. Vertebrobasilar Insufficiency Cardiovascular and Pulmonary Insufficiency, Patients undergoing any other treatment for the same condition from any other health practitioner, Neurological & psychological disorders 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Pain, Functionality and Joint Position Sense   At Baseline, 4 weeks
 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/10/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

 Title: Effectiveness of Spinal Mobilization with Arm Movement versus Neural Slider Technique on Pain, Functionality and Joint Position Sense in Cervical Spondylosis with Radiculopathy: A Comparative Study

Neck pain is a multifactorial disease, and is a major problem in modern society. Although neck pain may not be the most common musculoskeletal disorder. The global age standardised prevalence and incidence rate of neck pain were 3551.1 and 806.6 per 100,000. Cervical spondylosis is caused by a degeneration of the intervertebral discs. Cervical spondylosis, degenerative changes start in the intervertebral discs with osteophyte formation and involvement of adjacent soft tissue structures. Disc degeneration causes increased mechanical stress at the cartilaginous end plates at the vertebral body lip. This results in subperiosteal bone formation or osteophytic bars that extend along the ventral aspect of the spinal canal and, in some cases, encroach on nervous tissue. In cervical radiculopathy, a compressed nerve results in abnormal sensation and pain along with a neuropathic pain usually described as a “burning” or “shooting” pain.

Spinal Mobilization with Arm Movement – Lateral Glide is a manual therapy technique commonly applied in the cervical spine, typically used to treat patients with neck pain, Cervical Spondylosis with Radiculopathy, or Neck dysfunction. It combines a sustained lateral glide mobilization of the spine with active arm movement by the patient

The Neural Slider Technique, also known as nerve gliding or Neurodynamic sliding, is a gentle Neurodynamic intervention used in physiotherapy to treat patients with Cervical Spondylosis with Radiculopathy improve the mobility of peripheral nerves by promoting a sliding motion between the nerve and its surrounding tissues without putting significant tension on the nerve.

Patients with Cervical Spondylosis with Radiculopathy of age between 35 to 50 years. Were divided in two groups, Group A Conventional exercises group and Group B Experimental group. The treatment was given 4 days per week for 4 weeks. NPRS, Neck Disability Index (NDI), Joint Position Error (JPE) test for Cervical Proprioception used as outcome measures.

The patient will be screened on the basis of inclusion and exclusion criteria and their demographic data will be taken by an assessment Performa. Prior to the Commencement of the study, detailed procedure of the study will be explained to the Patients and a signed informed consent form will be taken from them. Then the Patient will be randomly assigned to a 4-week intervention protocol and allocated randomly to Group A and Group B. The subjects will be allocated to any of the two groups by random allocation using chit method. The therapist will measure pain, Functionality and joint position error before the intervention on the first day of the Treatment.  

 
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