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CTRI Number  CTRI/2025/07/090917 [Registered on: 15/07/2025] Trial Registered Prospectively
Last Modified On: 11/07/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   Comparing Different Homoeopathic Treatments used for Lichen Planus by using Different Homoeopathic books 
Scientific Title of Study   Comparative Study Of Different Prescription Based On Different Materia Medica In Lichen Planus 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Vishwa Anilbhai Patel 
Designation  PG SCHOLAR 
Affiliation  C D Pachchigar College Of Homoeopathic Medicine And Hospital 
Address  C D Pachchigar College Of Homoeopathic Medicine And Hospital Department Of Homoeopathic Materia Medica Post Graduation Division 2nd Floor Near Navjivan Circle Udhana Magdalla Road Surat

Surat
GUJARAT
395001
India 
Phone  9664755308  
Fax    
Email  vishwapatel793@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Gaurang Dave 
Designation  Professor Of Homoeopathic Materia Medica 
Affiliation  C D Pachchigar College Of Homoeopathic Medicine And Hospital 
Address  C D Pachchigar College Of Homoeopathic Medicine And Hospital Department Of Homoeopathic Materia Medica Post Graduation Division 2nd Floor Near Navjivan Circle Udhana Magdalla Road Surat

Surat
GUJARAT
395001
India 
Phone  8141699333  
Fax    
Email  drgaurangdave@gmail.com   
 
Details of Contact Person
Public Query
 
Name  Dr Gaurang Dave 
Designation  Professor Of Homoeopathic Materia Medica 
Affiliation  C D Pachchigar College Of Homoeopathic Medicine And Hospital 
Address  C D Pachchigar College Of Homoeopathic Medicine And Hospital Department Of Homoeopathic Materia Medica Post Graduation Division 2nd Floor Near Navjivan Circle Udhana Magdalla Road Surat

Surat
GUJARAT
395001
India 
Phone  8141699333  
Fax    
Email  drgaurangdave@gmail.com  
 
Source of Monetary or Material Support  
C D Pachchigar College Of Homoeopathic Medicine And Hospital Near Navjivan Circle Udhana Magdalla Road Surat India 395001 
 
Primary Sponsor  
Name  C D Pachchigar College Of Homoeopathic Medicine And Hospital 
Address  C D Pachchigar College Of Homoeopathic Medicine And Hospital Near Navjivan Circle Udhana Magdalla Road Surat  
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Vishwa Anilbhai Patel  C D Pachchigar College Of Homoeopathic Medicine And Hospital  Department Of Homoeopathic Matria Medica Post Graduation Division 2nd Floor
Surat
GUJARAT 
9664755308

vishwapatel793@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee Of C.D.Pachchigar College Of Homoeopathic Medicine and Hospital  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: L439||Lichen planus, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Individualized Homoeopathic Medicine  Individualized Homoeopathic Medicines Will Be Prescribed On The basis Of Totality Of Symptoms And Individual Susceptibility The Medicine Will Be Administered Orally In The Form Of Medicated Globules 4 To 6 Globules Per Dose The Intervention Will Be 15 To 30 Days 
Comparator Agent  NIL  NIL 
 
Inclusion Criteria  
Age From  1.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  1 Includes Cases Of All Age Group And Both Sexes
2 Cases Which Are Newly Diagnosed By me
3 Cases Which Are Already Diagnosed With or Without Any Conventional Treatment Taken 
 
ExclusionCriteria 
Details  1 Cases Which Having Advanced Skin Pathology Like Psoriasis , Skin Cancer ,Pemphigus vulgaris etc..
2 Patient Who Dropped Follow Up 
 
Method of Generating Random Sequence   Stratified randomization 
Method of Concealment   Case Record Numbers 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
To Compare the Prescription Based on J T Kent Homoeopathic Materia Medica ,Allens Keynote Metria Medica And On Lilenthal Therapeutics With Assesment The Changes And Extent Of Lichen Planus Lesions Like Itching,Pain,Quality Of Life And Determine The Frequency Of Repetition And Potency Response  9 Months 
 
Secondary Outcome  
Outcome  TimePoints 
To Understand Different Approach Of Prescription In Homoeopathy  9 Months 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   24/07/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="9"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

NEED FOR THE STUDY:

 

    I have found many cases of lichen planus , where patient immediately takes Conventional treatment for recovery. After taking conventional medicines and steroids, a Lot of patient suffers from adverse side effects. So, I want to conduct Research on lichen planus with diiffrent approach of prescription.

REVIEW OF LITERATURE

INTRODUCTION –

   Lichen planus (LP) is a chronic inflammatory condition affecting the skin   and mucosal surfaces. Lichen planus (LP) is a pruritic disease affecting the skin, mucous   membranes and hair follicles. The characteristic primary lesions are tiny, shiny, violaceous, flat-topped, polygonal papules. Surface shows scant adherent scales. Koebner phenomenon may occur.

     Lichen planus is an idiopathic papulosquamous disorder characterized by itchy pink to purple papules and plaques,occurring primarily on the scalp, extrimities , nails and mucous membranes.The term lichenoid is applied  to eruptions that clinically resemble lichen planus or have a similar histology, in particular  a heavy lymphocytic infiltrate immediately under the epidermis , the basal layer of which suffers the most damage.

CLINICAL FEATURES –

    Shiny, flat-topped, violaceous, polygonal papules of varying size, clustered around on the wristIrregularly linear or reticulate white striae (Wickham’s) are often seen in the papules.

    The lesions are usually itchy sometimes intensely so, but are occasionally asymptomatic. The inflammation usually subsides within 2 years and is commonly followed by post-inflammatory pigmentation .

     Mucosal lichen planus in form of whitish papular lesions, linearly disposed, may crisscross to form a lacy pattern, coalescence of papules may result in plaque formation. It accompanies cutaneous disease in about 50% of patients, and is common alone. The primary lesions are 2 to 10mm flat-topped papules with an irregular ,angulated border (purplr polygonal papules ).

    New lesions are pink to white ,but over time they become purple and sharply defined.New lesions may develop in areas of injury (kobner’s phenomenon ).

Distribution – Usually flexor areas are more affected. In males the genitals may also be involved in about 10% of patients

Variants

 • Persistent hypertrophic lesions, usually on the lower legs

Homoeopathic Management –

Homoeopathy treatment focus on the root cause, the triggering factors the pathological changes and the person as a whole. This is done by detailed medical history of the patient. The physical signs and symptoms appear because of disturbed vital functions either from external impressions having a depressing effect and the consequent reaction of the vital force

OBJECTIVES OF THE STUDY

Objectives –

To compare the prescription based on J.T.Kent Homoeopathic materia medica ,allen’s keynote materia medica and on lilenthal therapeutics.

 


 
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