| CTRI Number |
CTRI/2025/07/090905 [Registered on: 15/07/2025] Trial Registered Prospectively |
| Last Modified On: |
14/07/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Drug
Ayurveda |
| Study Design |
Single Arm Study |
|
Public Title of Study
|
Clinical Study Of Shirish Agad In Ringworm |
|
Scientific Title of Study
|
Clinical Study Of Shirish Agad In The Management Of Dadru |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dixit Thakur |
| Designation |
PG Student |
| Affiliation |
Uttranchal Ayurvedic College and Hospital |
| Address |
Department of Agad tantra, Uttranchal Ayurvedic medical college and Hospital,17 old mussorie road rajpur dehradun uttrakhand
Dehradun
UTTARANCHAL
248009
India |
| Phone |
07559687514 |
| Fax |
|
| Email |
dixitthakur07@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr. P.K Gupta |
| Designation |
Professor |
| Affiliation |
Uttranchal Ayurvedic College and Hospital |
| Address |
Department of Agad Tantra,Room No. 22, Uttranchal Ayurvedic Medical college And Hospital,17 old mussorie road rajpur dehradun uttrakhand
Dehradun
UTTARANCHAL
248009
India |
| Phone |
9412967100 |
| Fax |
|
| Email |
pkgayurveda@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dixit Thakur |
| Designation |
PG Student |
| Affiliation |
Uttranchal Ayurvedic College and Hospital |
| Address |
Department Of Agad Tantra, Uttranchal Ayurvedic Medical College And hospital,17 old mussorie road rajpur dehradun uttrakhand
Dehradun
UTTARANCHAL
248009
India |
| Phone |
07559687514 |
| Fax |
|
| Email |
dixitthakur07@gmail.com |
|
|
Source of Monetary or Material Support
|
| uttranchal ayurvedic medical college and hospital,17 old Mussorrie road,rajpur Dehradun,Uttrakhand, 248009 |
|
|
Primary Sponsor
|
| Name |
Dixit Thakur |
| Address |
Uttranchal Ayurvedic Medical College And Hospital 17 Old Mussorie Road Rajpur Dehradun, Uttrakhand, 248009 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Dixit Thakur |
Uttranchal ayurvedic medical college and hospital |
Department Of Agad Tantra, Room No.22,
Dehradun
UTTARANCHAL |
07559687514
dixitthakur07@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethical Committee of Uttranchal Ayurvedic College, Rajpur, Dehradun |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:L00-L08||Infections of the skin and subcutaneous tissue. Ayurveda Condition: DADRU-KUSHTHAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details | | 1 | Intervention Arm | Drug | Classical | | (1) Medicine Name: Shirish agad, Reference: Charak chikista sthan 23/218, Route: Topical, Dosage Form: Lepa Churna, Dose: 10(g), Frequency: tds, Bhaishajya Kal: Samudga, Duration: 1 Weeks, anupAna/sahapAna: No, Additional Information: -shirish agad for external application with sheetjala and to retain for 15 minutes and then should be washed with hot water | | 2 | Comparator Arm | Drug | Classical | | (1) Medicine Name: Shirish agad, Reference: Charak chikista sthan 23/218, Route: Topical, Dosage Form: Lepa Churna, Dose: 10(g), Frequency: tds, Bhaishajya Kal: Samudga, Duration: 1 Weeks, anupAna/sahapAna: No, Additional Information: Shirish agad for external application with sheetjala and to retain with 15 minutes and then should be washed with hot water | | 3 | Comparator Arm | Drug | Classical | | (1) Medicine Name: Shirish agad, Reference: Charak chikista sthan 23/218, Route: Topical, Dosage Form: Lepa Churna, Dose: 10(g), Frequency: tds, Bhaishajya Kal: Samudga, Duration: 1 Weeks, anupAna/sahapAna: No, Additional Information: Shirish agad for external application with sheetjala and to retain with 15 minutes and then should be washed with hot water |
|
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
10.00 Year(s) |
| Age To |
50.00 Year(s) |
| Gender |
Both |
| Details |
Sign And Symptoms: Kandu
Pidika
Raga
Rukshta
Utsanmandala |
|
| ExclusionCriteria |
| Details |
Patient under long standing medication.
Pregnant Women.
Lactating Women.
Chronicity more than 5 Years.
Pre Existing Skin Condition. |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Elimination of symptoms |
1 week |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| NIL |
NIL |
|
|
Target Sample Size
|
Total Sample Size="30"
Sample Size from India="30"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
Phase 3 |
|
Date of First Enrollment (India)
|
26/07/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="1"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Yet Recruiting |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Shirish Agad which is having both Vishagna as well as Kushtaghna property plays a very important role in reducing almost all the symptoms of Dadru like Kandu, Utsanmandala, Raag, Pidika And Twak rookshata. Sirish Agad was effective in Kandu, Pidiks etc. but in some cases Twak rookshata got slightly increased during treatment: it may be because of the ruksha property of the drug. It has been found to be of acute origin and was able to get good results, so it can be considered as Sadhya Vyadhi only and but proper hygene and food habits should be maintained. Topical applications are found to be producing significant improvement in the disease management, so even if it is used alone without any internal medications can produce favorable results. |