The prevalence of chronic rhinosinusitis (CRS) measured in epidemiologic studies is 5% to 12%. Chronic Rhinosinusitis is one of the important global health problems defined as inflammation of the mucous membrane of the nose and paranasal sinuses. Chronic rhinosinusitis refers to a condition that lasts at least 12 weeks, despite attempts to treat it, and causes at least two of the symptoms; nasal congestion, mucus discharge from the nose or mucus that drips down the back of the throat, facial pain, pressure, or fullness, a decreased sense of smell. The proximity of the brain to the sinuses makes the most dangerous complication of Chronic Rhinosinusitis, particularly involving the frontal and sphenoid sinuses, infection of the brain by   the invasion of anaerobic   bacteria through the   bones   or   blood vessels. Abscesses, meningitis and other life-threatening conditions may result. In extreme cases, the patient may experience mild personality changes, headaches, altered consciousness, visual problems, seizures, coma and possibly death. The treatment strategy for Chronic Rhinosinusitis mainly includes the use of topical decongestants, saline nasal drops, nasal saline irrigations, nasal steroids, antihistamines, antibiotics and in some cases surgical interventions. Even though not a life-threatening condition it produces difficulty in carrying out day to day activities and greatly affects the quality of life. Pinasa Roga is one such chronic disease which affects the nose and nasal passages. Pinasa is due to vitiated Vata Kapha, with Nasaavarodha (Nasal obstruction), Nasashosha (dryness of the nose), Gandha agyana (abnormal perception of smell) as the characteristic symptoms. The various etiological factors mentioned (faulty life style & regimen) leads to Agnimandya and Aama which is the main causative factor for the disease. Ayurveda being a life science advocated preventive and curative measures for the treatment of various chronic diseases. Earlier researches have proved the effectiveness of Ayurvedic treatment in the management of Pinasa Roga. Chitraka Haritaki Lehya is mentioned in Nasarogadhikara Chikitsa in Chakradutta (58/31-33). Shadbindu Taila is medication described in Bhaishajyaratnavali Siroroga chikitsa Prakarana for the management of almost all Urdhajatrugata Rogas (65/81- 83). Total 160 patients (80 at each participating center) will be included in the study. The observations and discussion will be made according to statistical analysis on different clinical & objective parameters and scores of questionnaires (Chronic Rhinosinusitis Questionnaire). This study has been proposed to evaluate the efficacy and safety of Administration of Shadbindu Taila Marsha Nasya and Chitraka Haritaki Avleha in Chronic Rhinosinusitis.