1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response - None of the above
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [ashleyeapen18@gmail.com].
   


6. For how long will this data be available start date provided 23-03-2028 and end date provided 23-03-2035?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - nil

Postoperative sore throat (POST) is a common complication following surgeries performed under general anaesthesia. The incidence of POST in patients undergoing tracheal intubation for general anaesthesia (GA) is 6.6-90 percentage. It is a double-blind randomized controlled trial to compare the effects of Dexmedetomidine and Magnesium Sulphate nebulisations on attenuation of sore throat, hoarseness of voice and cough in the postoperative period in patients undergoing elective surgeries under general anaesthesia with tracheal intubation. Patients fulfilling the inclusion criteria will be enrolled in the study and assessed prior to surgery. Predisposing factors such as cigarette smoking, gastroesophageal reflux disease, long-term use of corticosteroids and non-steroidal anti-inflammatory drugs will be captured. Patients will be informed about the study and informed consent will be obtained.

Participants will be randomly allocated into two groups using the fishbowl technique.One group will receive Dexmedetomidine at a dose of 1 mcg/kg, while the other group will receive 250 mg of Magnesium Sulphate. Dexmedetomidine (brand name: Dexem) and Magnesium Sulphate (brand name: Magneon) are available in the form of intravenous injection solutions, supplied in ampoules. They are diluted with normal saline for use via nebulisation. Both will be diluted with normal saline to a 5 mL solution in a 5 cc syringe and administered by a trained anaesthetist through a nebulization mask connected to wall-mounted, oxygen driven source (8 L/min, 50 psi) for 15 min. General anaesthesia (GA) will be induced after completing nebulization. Sore throat, hoarseness of voice, cough, haemodynamic parameters and respiratory rate will be measured at 0, 2, 4 and 6 hours from the time of extubation. POST would be graded on a four-point scale (0–3). This study seeks in formulating interventions for decreasing sore throat, cough and hoarseness of voice in the postoperative period that would help to improve the quality of postoperative recovery.