Need for the study Caries is defined as the process of enamel or dentin dissolution that is caused by microbial action at the tooth surface as is mediated by physiochemical flow of water dissolved ions (Ostrom,1980).Vital pulp therapy is a conservative treatment modality that seeks to preserve the vitality and functionality of the dental pulp that has been exposed due to caries or trauma. Indirect Pulp Capping is a single step procedure that entails the Selective Caries Removal (SCR) of heavily infected superficial necrotic dentin while the affected firm dentin is left over the pulp. Pulpotomy can be defined as the complete removal of coronal portion of the dental pulp, followed by placement of suitable dressing or medicament that will promote healing and preserve the vitality of tooth (Finn, 1959). Bisco has recently launched a new dual cured resin-modified calcium silicate-based (Theracal PT). Its primary indication is pulpotomy since it can be used in adequate thickness. It can also be utilized as a direct and indirect pulp capping material as a base under various substrates. Biodentine has been introduced and progressed (through the biosilicate technology ) with the purpose of incorporating the increased biocompatibility and the bioactivity of calcium silicates, producing improved features that cause it to be better than any other calcium silicate–based cements. Thus, the aim of the study is intended to comparatively evaluate Theracal PT (Bisco, America) and Biodentine (Septodont, France) for two different vital pulp therapies in primary molars. Aim of the study: To evaluate and compare Theracal PT and Biodentine for two different vital pulp therapies in primary molars. Objectives of the study: 1. To evaluate and compare Theracal PT (Bisco, America) and Biodentine (Septodont, France) for Indirect Pulp Capping on the basis of clinical and radiographic parameters. 2. To evaluate and compare Theracal PT (Bisco, America) and Biodentine (Septodont, France) for Pulpotomy on the basis of clinical and radiographic parameters. Source of data Type of study – Comparative study In-vitro/in-vivo/survey – in – vivo study Source from where the cases, patients, subjects, or study material will be selected- Dept Of Pediatric and Preventive Dentistry, Dr. D. Y Patil Dental College and Hospital, Pimpri, Pune. Name and place where the study will be conducted- Dept Of Pediatric and Preventive Dentistry, Dr. D. Y Patil Dental College and Hospital, Pimpri, Pune Method of data collection Sampling technique used – Convenience sampling Sample size – 144 Size of each group: 36 Group I: Indirect Pulp Capping using Theracal PT (Bisco, America) Group II: Indirect Pulp Capping using Biodentine (Septodont, France) Group III: Pulpotomy using Theracal PT (Bisco, America) Group IV: Pulpotomy using Biodentine (Septodont, France) Inclusion criteria: 1. Children between 4-7 years of age. 2. Participants parents who give consent to participate in the study. 3. Atleast 1 restorable primary mandibular 2nd molar with caries extending in dentin without pulpal approachment. 4. Caries involving one-third of dentin on radiographic examination 5. Atleast 1 restorable primary mandibular 2nd molar with deep occlusal caries indicated for pulpotomy. 6. Vital tooth with healthy periodontium. 7. Caries involving coronal portion of pulp on radiographic examination. Exclusion criteria: 1. Spontaneous or nocturnal pain and Pain on pressure. 2. Intraoral swelling and Sinus tract. 3. Pathological mobility or Furcation involvement. 4. Peri-radicular radiolucency and Internal or external root resorption. 5. Widening of periodontal ligament and Discontinuity of lamina dura. 6. Patients with any systemic diseases. 7. Children with special health care needs. MATERIALS: Theracal PT (Bisco) Biodentine (Septodont) Rubber dam (Coltene) Glass Ionomer Cement (GC) Local anaesthesia (2% lignocaine with 1:200000 adrenaline, NEON) 0.12% Chlorhexidine Gluconate (AMMDENT) INSTRUMENTS: Diagnostic instruments Spoon excavator GIC Mixing Pad Agate spatula ARMAMENTERIUM : Mouth mask, Head cap Gloves Procedure: Patients will be selected according to the inclusion and exclusion criteria. The study procedure will be explained to each participant’s parents and necessary informed consent from the parent/guardian and assent from the child will obtained in a language they understand. Teeth will be isolated using rubber dam after administration of local anaesthesia. Patients will be divided into four groups. Group 1: Indirect Pulp Capping using Theracal PT N = 36 Group 2: Indirect Pulp Capping using Biodentine N = 36 Group 3: Pulpotomy using Theracal PT N = 36 Group 4: Pulpotomy using Biodentine N = 36 For Indirect Pulp Capping, Caries will be removed with slow speed round bur. Peripheral caries will be removed with spoon excavator, if any. Theracal PT will be applied in 2mm thickness and light cured for 10 sec as per manufacturer instructions followed by GIC restoration. Biodentine will applied in 2mm thickness as per manufacturer instructions followed by GIC restoration. For Pulpotomy, Caries will be removed with slow speed round bur before pulp exposure. Once pulp will be exposed, roof of the pulp chamber will be removed using no. 330 carbide bur. Spoon excavator to be used to remove pulp remnants adhering to pulp floor. Theracal PT will be applied in 2mm thickness and light cured for 10 sec as per manufacturer instructions followed by GIC restoration. Biodentine will applied in 2mm thickness as per manufacturer instructions followed by GIC restoration. Follow up for clinical and radiographic evaluation will be done at 1 and 6 months. Data will be recorded and tabulated and results will be analyzed using statistical analysis method. Method of data analysis McNemar test Cox regression for survival |