| CTRI Number |
CTRI/2025/06/089811 [Registered on: 30/06/2025] Trial Registered Prospectively |
| Last Modified On: |
28/06/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Physiotherapy (Not Including YOGA) |
| Study Design |
Randomized, Parallel Group Trial |
|
Public Title of Study
|
How Different Types of Exercise Improve Memory and Self-Control in Young Adults |
|
Scientific Title of Study
|
Effects Of High Intensity Interval Training and Moderate Intensity Continuous Training to Improve Cognitive Inhibitory Control and Working Memory in Young Adults |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Nishat Nazeer |
| Designation |
Post Graduate Scholar |
| Affiliation |
Jamia Hamdard |
| Address |
Room No 503 - B, Neurology Lab, 5th Floor, Central Library Building, Department of Physiotherapy, SNSAH, Jamia Hamdard
South
DELHI
110062
India |
| Phone |
7667802105 |
| Fax |
|
| Email |
nazeernishat909@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Prachi Tiwari |
| Designation |
Assistant Professor |
| Affiliation |
Jamia Hamdard |
| Address |
Room No.543, Central Library Building, Department of Physiotherapy, SNSAH, Jamia Hamdard
South
DELHI
110062
India |
| Phone |
9811644726 |
| Fax |
|
| Email |
prachi.tiwari@jaiahamdard.ac.in |
|
Details of Contact Person
Public Query
|
| Name |
Prachi Tiwari |
| Designation |
Assistant Professor |
| Affiliation |
Jamia Hamdard |
| Address |
Room No.543, Central Library Building, Department of Physiotherapy, SNSAH, Jamia Hamdard
South
DELHI
110062
India |
| Phone |
9811644726 |
| Fax |
|
| Email |
prachi.tiwari@jaiahamdard.ac.in |
|
|
Source of Monetary or Material Support
|
| Jamia Hamdard, Hamdard Nagar, New Delhi - 110062 |
|
|
Primary Sponsor
|
| Name |
Jamia Hamdard |
| Address |
Hamdard Nagar, New Delhi - 110062 |
| Type of Sponsor |
Research institution and hospital |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Prachi Tiwari |
Department of Physiotherapy, Jamia Hamdard |
Room No. 503B, Neurology Lab, Department of Physiotherapy, Jamia Hamdard
South
DELHI |
9811644726
prachi.tiwari@jamiahamdard.ac.in |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Jamia Hamdard Institutional Ethics Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Healthy Human Volunteers |
Collegiate Subjects |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Comparator Agent |
Control Group Educational Intervention |
1.One educational session per week for 6 weeks.
2.Each session of 20 minutes, conducted in small groups.
3.Content includes
a.Benefits of physical activity for cognitive and physical health
b.Balanced diet and hydration guidance
c.Mental health education like stress management, sleep hygiene
d.Avoidance of smoking and alcohol
e.Healthy lifestyle strategies to support cognitive function
4.Sessions delivered in simple, accessible language.
|
| Intervention |
High Intensity Interval Training |
1.Five minute warm up at 40 to 50 percent HRmax.
2.Six second sprints at 85 to 90 percent HRmax with 30 second active recovery.
3.Treadmill speed and incline adjusted to maintain target HR.
4.HR and Oxygen Saturation measured pre and post sprint.
5.Rate of Perceived recorded using Borg Scale.
6.Continuous HR monitored with chest strap.
7.Three sessions per week for 6 weeks.
8.All sessions supervised.
9.Verbal encouragement provided.
|
| Intervention |
Moderate Intensity Continuous Training |
1.Two minutes treadmill warm up.
2.Twenty minutes of continuous running at 60 to 70 percent heart rate reserve.
3.Two minutes cool down.
4.Borg Rate of Perceived Exertion recorded post session.
5.Frequency will be 3 sessions per week for 6 weeks.
6.All sessions supervised by trained personnel.
|
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
25.00 Year(s) |
| Gender |
Both |
| Details |
1.Both male and female participants were included
2.Body Mass Index Within the normal range of 18.5 to 24.9 kilogram per meter square
3.Cognitive status Score greater than 26 on the Mini-Mental State Examination, indicating normal cognitive function
4.Successfully cleared the Physical Activity Readiness Questionnaire (PAR-Q) to ensure safety for participation in exercise interventions
|
|
| ExclusionCriteria |
| Details |
1.No participation in HIIT or vigorous exercise programs in the past 6 months
2.Subjects with history of diagnosed cardiovascular diseases
3.Diagnosed respiratory diseases
4.Neurological conditions
5.Diagnosed with Type 1 or uncontrolled Type 2 diabetes
6.Obesity with BMI greater than 35 kilogram per metre square
7.History of recent injuries or surgeries
8.Visual or Hearing Sensory impairments.
9.Post-COVID-19 individuals with lingering symptoms
|
|
|
Method of Generating Random Sequence
|
Computer generated randomization |
|
Method of Concealment
|
Sequentially numbered, sealed, opaque envelopes |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
Computerized Modified Stroop Task
The Digit Span Test
Word Recall Test
|
Baseline, After four weeks, After Six weeks |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Nil |
Nil |
|
|
Target Sample Size
|
Total Sample Size="90"
Sample Size from India="90"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
09/07/2025 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
A total of 90 healthy young
adults will be recruited and assigned into three groups. High Intensity
Interval Training, Moderate Intensity Continuous Training, and a Control Educational
Intervention group. After obtaining informed consent, participants will undergo
baseline assessments including anthropometric measures, a graded exercise test,
and cognitive tests Computerized Modified
Stroop Task, The Digit Span Test, Word Recall Test. Participants in the HIIT
group will perform repeated short sprints with recovery periods, while the MICT
group will engage in continuous moderate running. The control group will
receive weekly educational sessions on physical and cognitive health. Interventions
will continue for six weeks under supervision, with cognitive and physiological
responses monitored throughout. |