Lower limb amputations are regularly performed as a life saving surgeries in the underlying circumstances of sepsis, peripheral arterial disease or trauma. Peripheral vascular disease (PVD) and diabetes mellitus (DM) have been identified as primary risk factors for lower limb amputations. The reasons for limb loss can be classified into the following categories: patient-specific issues such as comorbidities, presence of foot lesions, anatomical factors, and healthcare-related factors like access to healthcare and medical insurance. Indications for amputation are related to the degree of tissue necrosis or viability, and it is performable in either a single operation or a staged manner. In general, soft tissue quality and the ability to obtain bone coverage will guide the adequacy of the level of amputation. Patients who undergo LEA usually have comorbidities, including hypertension, heart failure, and end-stage renal disease and are likely to be in an older age group. Furthermore, these patients have advanced systemic atherosclerotic disease involving not only the peripheral limbs but also the coronary, cerebral, and renal circulations. Hence Anaesthetic management for such patients is chosen carefully. Because of ultrasound guidance, the usage of regional anaesthesia (RA) has increased since 2005. Additionally, compared to general anaesthesia (GA), RA has a number of physiological advantages, including as better stump flow, preservation of the body’s physiological reaction to stress, and comparable or greater analgesia following surgery.  Compared with GA, neuraxial anaesthesia, in particular, has been associated with lower 30-day mortality and decreased morbidity, less blood loss, fewer surgical site infections, and a decreased rate of admission to critical care services after elective total hip or knee arthroplasty. The aim of the study is to compare the impact of Regional Anaesthesia and General Anaesthesia on the Length of Hospital stay and mortality and morbidity of patients in the 30 day post-op period in Indian Setting