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CTRI Number  CTRI/2025/07/090253 [Registered on: 07/07/2025] Trial Registered Prospectively
Last Modified On: 07/07/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized Factorial Trial 
Public Title of Study   Dynamic proprioception training versus strengthening program among patellofemoral pain syndrome in sprinters. 
Scientific Title of Study   Effectiveness of dynamic proprioception training versus strengthening program on pain, balance and functional performance among patellofemoral pain syndrome in sprinters. 
Trial Acronym  nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Devadharshini B 
Designation  PG student  
Affiliation  Saveetha college of physiotherapy 
Address  A5 5th Floor Health Science block, Saveetha college of Physiotherapy, Saveetha Nagar, Thandalam, Kanchipuram, Tamil Nadu

Kancheepuram
TAMIL NADU
602501
India 
Phone  9176713934  
Fax    
Email  bdevadharshini2002@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr S Subramanian 
Designation  Professor 
Affiliation  Saveetha college of physiotherapy 
Address  A5 5th Floor Health Science block, Saveetha college of Physiotherapy, Saveetha Nagar, Thandalam, Kanchipuram, Tamil Nadu

Kancheepuram
TAMIL NADU
602501
India 
Phone  9003913514  
Fax    
Email  subramanian.scpt@saveetha.com  
 
Details of Contact Person
Public Query
 
Name  Dr S Subramanian 
Designation  Professor 
Affiliation  Saveetha college of physiotherapy 
Address  A5 5th Floor Health Science block, Saveetha college of Physiotherapy, Saveetha Nagar, Thandalam, Kanchipuram, Tamil Nadu

Kancheepuram
TAMIL NADU
602501
India 
Phone  9003913514  
Fax    
Email  subramanian.scpt@saveetha.com  
 
Source of Monetary or Material Support  
A5 5th floor,Health Science block Saveetha college of Physiotherapy,Saveetha nagar,Thandalam,Kancheepuram,Tamil Nadu Kancheepuram TAMIL NADU 602105 India 
 
Primary Sponsor  
Name  Devadharshini B 
Address  Room no.A5 5th floor Health Science block Saveetha college of Physiotherapy Saveetha nagar Thandalam Kancheepuram Tamil Nadu Kancheepuram TAMIL NADU 602105 India 
Type of Sponsor  Other [self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Devadharshini B  Saveetha college of physiotherapy  Room no.A5 5th floor Health Science block Saveetha college of Physiotherapy Saveetha nagar Thandalam Kancheepuram Tamil Nadu Kancheepuram TAMIL NADU 602105 India
Kancheepuram
TAMIL NADU 
9176713934

bdevadharshini2002@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Scientific Review Board  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  sprinters with patellofemoral pain syndrome.  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Dynamic proprioception training  Single leg stance, single leg hop,lateral band walking,mini hurdle,jump-land-stick. 
Comparator Agent  Strengthening program  Single leg bridge,wall squat,walking lunges,bulgarian split squat and terminal knee extension. 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  25.00 Year(s)
Gender  Both 
Details  1.Anterior knee pain of PFPS for atleast 3 months.
2.Having pain between 3 to 6 in NPRS.
3.Pain reproduced during functional tests such as squat,step down or patellar compression.
4.Greater than 4cm difference in anterior reach direction between legs.
5.Experience pain in following test;
a.Apprehension test
b.Patellar compression test
c.Clarke test. 
 
ExclusionCriteria 
Details  1. History of acute knee trauma (e.g., ligament rupture, meniscal tear, or patellar dislocation).
2. History of knee surgery, bursitis and arthritis.
3. History of patella subluxation or dislocation, anterior or posterior cruciate ligament insufficiency.
4. Referral pain from spinal cord or nerve roots.
 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant, Investigator and Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Numeric pain rating scale  8 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
6 metered hop test  8 weeks 
Y balance test  8 weeks 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "60"
Final Enrollment numbers achieved (India)="60" 
Phase of Trial   N/A 
Date of First Enrollment (India)   30/07/2025 
Date of Study Completion (India) 07/02/2026 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="0"
Months="1"
Days="15" 
Recruitment Status of Trial (Global)   Completed 
Recruitment Status of Trial (India)  Completed 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

                  Patellofemoral Pain Syndrome (PFPS) is one of the most prevalent overuse injuries among athletes, particularly sprinters. It is characterized by anterior knee pain that worsens with activities such as running, squatting, or stair climbing. The repetitive high-impact loading experienced during sprinting can exacerbate patellofemoral joint stress, impairing athletic performance. Strengthening of the quadriceps and hip muscles to improve joint mechanics and reduce pain. While beneficial, these programs may not fully restore proprioception and neuromuscular control—key elements in maintaining knee stability during sprinting. Impaired proprioception has been linked to poor balance and increased risk of re-injury. Dynamic proprioception training targets joint position sense and neuromuscular coordination, offering a potentially superior approach to improving functional performance in athletes. This study is needed to determine which approach yields better outcomes in pain reduction, balance improvement, and overall functional performance, providing evidence-based guidance for athletic rehabilitation strategies.

 

 

 
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