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CTRI Number  CTRI/2026/02/103735 [Registered on: 12/02/2026] Trial Registered Prospectively
Last Modified On: 09/02/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Other (Specify) [YOGA]  
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Effect of Yoga Based Lifestyle Intervention on Symptom Burden and Qualityvof life in patients with ventral Hernia: A Randomised controlled study 
Scientific Title of Study   A prospective randomised controlled study on the role of Yoga Therapy in alleviating post operatiove pain and distress in patients undergoing Laparoscopic repair of Ventral Hernia 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Ankur Yadav 
Designation  MS General Surgery 
Affiliation  All India Institute Of Medical Sciences, New Delhi 
Address  Department of Surgery, AIIMS New Delhi. PIN- 110029

South
DELHI
110029
India 
Phone  9818041768  
Fax    
Email  ankuryadavay786@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Devender Singh 
Designation  Assistant Professor  
Affiliation  All India Institute Of Medical Sciences, New Delhi 
Address  Room No. 413 Surgery Block AIIMS New Delhi. PIN- 110029

South
DELHI
110029
India 
Phone  9813643337  
Fax    
Email  devender_singh@aiims.edu  
 
Details of Contact Person
Public Query
 
Name  Dr Ankur Yadav 
Designation  MS General Surgery 
Affiliation  All India Institute Of Medical Sciences, New Delhi 
Address  Department of Surgery Aiims New Delhi. PIN- 110029

South
DELHI
110029
India 
Phone  9818041768  
Fax    
Email  ankuryadavay786@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  Dr. Devender Singh 
Address  Room NO. 413, Aiims, New Delhi. PIN- 110029 
Type of Sponsor  Other [SELF] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Ankur Yadav  All India Institute Of Medical Sciences, New Delhi  Unit- 1 Department of Surgical Disciplines, Aiims New Delhi, PIN-110029.
South
DELHI 
9818041768

ankuryadavay786@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institute Ethics Committee for PG Reasearch  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: K43||Ventral hernia,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Standard post op care in IPOM and IPOM plus patients  Standard post op care will be given to this arm. 
Intervention  Yoga therapy   1.The yogasanas will be simpler, may be helpful to reduce abdominal pressure and strengthen the abdominal muscles. 2. Duration/ schedule : 40 to 45 minutes daily, 5 days a week, for 1 months 3. Mode : First 2 weeks offline (physical) mode for training and rest 2 weeks online mode (patients can practice yogasana at their home under the supervision of a yoga therapist). Each yoga session would be as follows- 1. Prayer 2. Yogic Sukshma Vyayama - Griva shakti vikasaka - Skandha chakra - Purna bhuja shakti vikasaka - Janu shakti vikasaka kriya - Gulpha pada- pristha-pada tala shakti vikasaka kriya 3. Asana - Standing - Utkatasana - Virabhadrasana 2 Sitting - Vajrasana - Chakki chalanasana - Marjariasana - Naukasana Supine - Eka pada uttana padasana - Eka pada pawanmuktasana - Pawanmuktasana - Shavasana 4. Pranayama - Anulom Vilom - Bhramari 5. Prayer  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  65.00 Year(s)
Gender  Both 
Details  -Patients with ventral hernia-Reducible, Uncomplicated (primary as well as incisional with defect size less than 6cm) who are planned for laparoscopic mesh repair(IPOM or IPOM plus).
-Duration of surgery less than 2hrs
-Age more than or equal to 18 years and less than 65 years
- BMI more than or equal to 18.5 and less than 35
 
 
ExclusionCriteria 
Details  - Unfit for General anaesthesia and Laparoscopy - deranged coagulation profile.
- Hernias other than ventral hernias.
- Hernias undergoing Laparoscopic eTEP or Laparoscopic vTAPP repair
- Irreducible or strangulated hernias.
- Parastomal or recurrent hernias or incisional hernias.
- Rectal diastasis or femoral hernia pts.
- Physically challenged.
- Hyperesthesia.
- Pregnant, OSA, active TB, history of seizures, dementia, previous abdominal surgery, orthopedic disorders(IVDP, sciatica).
- Uncooperative or Refusal.
- Mental retardation.
 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
Post op Pain using Visual assessment pain scale  6hours, 8hours, 1week, 4weeks 
 
Secondary Outcome  
Outcome  TimePoints 
Mood, chronic inguinal pain, analgesic requirements, functional outcomes  12,24,48 hours post op and them 1/2/4/8 weeks post op 
 
Target Sample Size   Total Sample Size="60"
Sample Size from India="60" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 4 
Date of First Enrollment (India)   01/03/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="2"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

  While the literature on yoga therapy in surgical patients is extensive, there is a paucity of studies specifically addressing its role in abdominal surgeries such as ventral hernia repair, where immediate postoperative pain and chronic pain are big issues which still need to be addressed. Return to normal work and physical activity can also be hindered as a result of inguinal pain.

A pilot study by Sharma et al [24] investigated the feasibility and preliminary efficacy of yoga therapy in improving post-operative outcomes in patients undergoing abdominal surgeries. Although the study focused on a heterogeneous group of abdominal surgery patients, including those undergoing hernia repair, it reported promising results in pain reduction and functional improvement following yoga therapy.

   Understanding the underlying mechanisms of action of yoga therapy in pain management is crucial for elucidating its potential benefits in surgical patients. Research suggests that yoga interventions may modulate pain perception through various physiological and psychological mechanisms, including activation of the parasympathetic nervous system, reduction of inflammation and stress hormones, enhancement of self-awareness and mindfulness, and promotion of relaxation and coping skills. Reviews by Cramer et al [5] provide comprehensive overviews of the mechanisms and neurobiological effects of yoga therapy in pain management across different populations.

   Assessing patient preferences and acceptability of yoga therapy interventions is essential for informing the design and implementation of clinical trials in surgical populations. Qualitative studies exploring patient experiences with yoga therapy in pain management have highlighted factors such as perceived effectiveness, enjoyment, sense of empowerment, and satisfaction with the holistic approach. Understanding patient perspectives can inform patient-centred care and enhance adherence to yoga interventions in post-operative settings.

   While the primary focus of this study is on post-operative pain management, exploring the broader effects of yoga therapy on surgical outcomes and to provide valuable context and insights. Studies by Innes and Vincent[18] and Bussing et al.[25] have investigated the effects of yoga interventions on perioperative anxiety, stress, immune function, and recovery outcomes in surgical patients. Considering these broader outcomes alongside pain management can enhance the comprehensiveness and inform holistic approaches to post-operative care.

   Patient education and empowerment are integral components of holistic healthcare delivery. Research by Telles et al.[26] and Evans et al.[27] has explored the role of yoga therapy in enhancing patient self-management skills, self-efficacy, and self-care behaviours, which can contribute to improved post-operative outcomes and long-term well-being. Integrating patient education components into yoga therapy interventions can foster active patient engagement and facilitate self-directed pain management strategies.

   Evaluating the cost-effectiveness of complementary therapies such as yoga in surgical care is essential for healthcare resource allocation and decision-making. Economic evaluations conducted by Herman et al.[28] and Saper et al.[29] have assessed the cost-effectiveness and cost-benefit ratios of yoga interventions in various clinical populations, highlighting potential healthcare cost savings and improved health outcomes. Investigating the cost-effectiveness of yoga therapy in post-operative pain management can provide valuable evidence for healthcare policymakers and stakeholders.

 In conclusion, the literature suggests that yoga therapy holds promise as a complementary intervention in alleviating post-operative pain and improving overall well-being.

   The current literature supports the potential role of yoga in reducing inflammatory markers in post-operative patients. While direct evidence in ventral hernia patients is limited, the broader body of research suggests that yoga can effectively modulate inflammation through various mechanisms.

   Further research specifically focusing on ventral hernia patients, is warranted to confirm these benefits and to establish standardized protocols for integrating yoga into standard post-operative care 
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