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CTRI Number  CTRI/2025/03/081914 [Registered on: 07/03/2025] Trial Registered Prospectively
Last Modified On: 05/03/2025
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   Cross Sectional Study 
Study Design  Other 
Public Title of Study   Validation of the Nadi Pulse Instrument (Pulse Testing Tool) 
Scientific Title of Study   Validation of the nadi pulse instrument (pulse assessment equipment) 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Rupashri Nath 
Designation  Assistant Professor 
Affiliation  All India Institute Of Ayurveda, New Delhi 
Address  Room No. 306, 3rd Floor, Academic Block, Department Of Roga Nidana Evum Vikriti Vigyana, All India Institute Of Ayurveda, Gautam Puri, Sarita Vihar, New Delhi-110076

South
DELHI
110076
India 
Phone  6398552356  
Fax    
Email  rupashrinadi.24@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Rupashri Nath 
Designation  Assistant Professor 
Affiliation  All India Institute Of Ayurveda, New Delhi 
Address  Room No. 306, 3rd Floor, Academic Block, Department Of Roga Nidana Evum Vikriti Vigyana, All India Institute Of Ayurveda, Gautam Puri, Sarita Vihar, New Delhi-110076


DELHI
110076
India 
Phone  6398552356  
Fax    
Email  rupashrinadi.24@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Shalini Rai 
Designation  Associate Professor 
Affiliation  All India Institute Of Ayurveda, New Delhi 
Address  Room No. 306, 3rd Floor, Academic Block, Department Of Roga Nidana Evum Vikriti Vigyana, All India Institute Of Ayurveda, Gautam Puri, Sarita Vihar, New Delhi-110076

South
DELHI
110076
India 
Phone  9389423843  
Fax    
Email  vd.raishalini@gmail.com  
 
Source of Monetary or Material Support  
START-UP (NADI PULSE) All India Institute of Ayurveda, Gautam Puri, Sarita Vihar, Delhi- 110076, India 
 
Primary Sponsor  
Name  Startup Nadi Pulse SIIC IITK IIT Kanpur Kanpur Uttar Pradesh  
Address  SIIC IITK IIT Kanpur Kanpur Uttar Pradesh- 208016 
Type of Sponsor  Other [Private Company] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Rupashri Nath  All India Institute Of Ayurveda, New Delhi  Room No. 306, 3rd Floor, Academic Block, Department Of Roga Nidana Evum Vikriti Vigyana, All India Institute Of Ayurveda, Gautam Puri, Sarita Vihar, New Delhi-110076
South
DELHI 
06398552356

rupashrinadi.24@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Division of translational research and biostatistics all india institute of ayurveda institutional ethics committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  apparently healthy 
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
 
Inclusion Criteria  
Age From  21.00 Year(s)
Age To  40.00 Year(s)
Gender  Both 
Details  Apparently healthy participants will be selected 
 
ExclusionCriteria 
Details  1. Individuals with known cardiac arrhythmias.
2. Individuals with peripheral vascular diseases affecting pulse palpation.
3. Individuals unable to provide informed consent or cooperate with the assessment.
4. Volunteers with physical disability (Handicapped -no arms)
 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
TO ASSESS THE RELIABILITY OF NADI PULSE EQUIPMENT  1 YEAR 
 
Secondary Outcome  
Outcome  TimePoints 
Through rigorous assessment of reliability and validity, this study will provide valuable insights into the effectiveness and accuracy of the Pulse Assessment Tool. The findings will inform its suitability for clinical use and contribute to improving patient care and diagnosis.  1 YEAR 
 
Target Sample Size   Total Sample Size="300"
Sample Size from India="300" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/04/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Nadi Pariksha is one among the asta-sthana (eight-fold) examination. Nadi Pariksha is a diagnostic skill, based on the tactile sensitivity of the physicians. elicited by radial artery pulsations. This is an ancient traditional Ayurvedic technique known to Indian physicians since the Vedic era. This is a diagnostic way to assess health status of an individual in terms of dosha levels, to know the untold symptoms, diagnosis and prognosis of disease. The references of the term naadi is found in Charak Samhita.  Bhela samhita, Harita samhita, Susruta samhita, Yogashastra and Sidhashastra Sharangadhara Samhita, Yogratnakar, Basavarajiyam texts.  This art and knowledge of pulse diagnosis was accepted and practiced in various medical therapies of the world, like in Greek, Chinese, Turkish, Arab, Homeopathy, Allopathic from many years. This diagnostic method has got its significant role in assessment of the physiological and pathological conditions. 

Naadi pariksha was developed and practiced as a family tradition by naadi vaidyas. This assessment depends on good tactile sensitivity of physician’s fingers. To maintain the secrecy of knowledge, the procedure and the skill remained with the family members of the particular tradition. As this pariksha (examination) is subjective there is difficulty in teaching and learning of this skill. This has led to loss of its wide practise in diagnosis of disease. This knowledge of naadi pariksha is sparsely found and scattered in some of the ayurveda texts.

Naadi pariksha requires dedicated concentration, good tactile sensitivity in a physician. Its difficulty in teaching and learning has led to loss of practise in diagnosis of disease. There are various instruments designed for the examination of pulse, but these instruments’ have some lacuna like lack of data capturing methods, some instruments do not follow the classical Ayurveda method, some other instruments study the heartrate variability. This study, efforts to validate an objective diagnostic tool named as Nadipulse.

 
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