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CTRI Number  CTRI/2025/02/080380 [Registered on: 12/02/2025] Trial Registered Prospectively
Last Modified On: 28/01/2025
Post Graduate Thesis  Yes 
Type of Trial  Observational 
Type of Study   Cohort Study 
Study Design  Other 
Public Title of Study   To estimate the economic impact of suicide and suicide attempts in India 
Scientific Title of Study   Economic Burden of Suicide and Suicide Attempts in India: Estimation from a Societal Perspective 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Nikhil Jain 
Designation  Research Fellow 
Affiliation  Indian Law Society 
Address  Centre For Mental Health Law and Policy Law College Road Pune
Law College Road, Erandwane, Pune
Pune
MAHARASHTRA
411027
India 
Phone  9074770345  
Fax    
Email  jain2009nikhil@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Animesh Patel 
Designation  HOD, Psychiatry Department 
Affiliation  Civil Hospital Mehsana 
Address  Civil Hospital near ISBT Mehsana

Mahesana
GUJARAT
384001
Other 
Phone    
Fax    
Email  dr.animeshpatel87@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Nikhil Jain 
Designation  Research Fellow 
Affiliation  Indian Law Society 
Address  Centre For Mental Health Law and Policy Law College Road Pune
Law College Road, Erandwane, Pune
Pune
MAHARASHTRA
411027
India 
Phone  9074770345  
Fax    
Email  jain2009nikhil@gmail.com  
 
Source of Monetary or Material Support  
Infrastructural support by Civil Hospital Mehsana and Lions Hospital, Mehsana ( Department of Psychiatry) Mehsana 384001 Gujarat India 
 
Primary Sponsor  
Name  Nikhil Jain 
Address  CAPHRI Maastricht University The Netherlands 
Type of Sponsor  Other [University ] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Animesh Patel HOD Department of Psychiatry  Mehsana Civil hospital , Near ISBT, & Lions Hospital, Mehsana, Gujarat  Department Of Psychiatry, Civil Hospital, Near ISBT, Mehsana, Gujarat & Lions Hospital( Department of Psychiatry Link Road Mehsana 384001 India
Mahesana
GUJARAT 
8238011270

dr.animeshpatel87@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Indian Law Society  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: T148||Other injury of unspecified body region,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  NIL  Not Applicable 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  99.00 Year(s)
Gender  Both 
Details  The study will involve patients admitted to the emergency department, ICU, or other hospital units following a suicide attempt. In situations where the individual who attempted suicide is too unwell to participate in the study or is a minor (below 18 years of age), a close family caregiver will be engaged to provide information about the resources consumed and utility loss (health-related quality of life) 
 
ExclusionCriteria 
Details  People who cannot understand the local language 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Economic burden of suicide and suicide attempts  Baseline, 1 month follow-up, 3 month follow-up, 6 month follow-up 
 
Secondary Outcome  
Outcome  TimePoints 
Health-related quality of life  Baseline, 1-month follow-up, 3-month follow-up, 6-month follow-up 
 
Target Sample Size   Total Sample Size="220"
Sample Size from India="220" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   27/02/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - YES
  1. What data in particular will be shared?
    Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).

  2. What additional supporting information will be shared?
    Response -  Study Protocol
    Response -  Statistical Analysis Plan
    Response - Informed Consent Form

  3. Who will be able to view these files?
    Response - Researchers who provide a methodologically sound proposal.

  4. For what types of analyses will this data be available?
    Response - To achieve aims in the approved proposal.

  5. By what mechanism will data be made available?
    Response - Proposals should be directed to [n.jain@maastrichtuniversity.nl].

  6. For how long will this data be available start date provided 27-02-2027 and end date provided 27-02-2032?
    Response - Beginning 3 months and ending 5 years following article publication.

  7. Any URL or additional information regarding plan/policy for sharing IPD? 
    Additional Information - NIL
Brief Summary  

This study aims to quantify the economic burden of suicide and suicide attempts in India, focusing on the societal costs associated with these events. Recognizing the limitations of existing gross costing methods, which often overlook sector-specific impacts, the study introduces a tailored Resource-Use Measure (RUM) instrument to capture granular costs across sectors such as healthcare, law enforcement, and patient and family and their productivity losses. Additionally, it incorporates a Health-Related Quality of Life (HRQoL) assessment using EuroQOL (EQ-5D-5L) to account for utility loss among suicide attempt survivors.

 

The study adopts a retrospective, incidence-based design and employs advanced statistical approaches, including nonparametric tests for subgroup cost comparisons and Generalized Linear Mixed Models (GLMMs) for longitudinal data analysis. Bootstrapping and sensitivity analyses will ensure the robustness of the findings. By identifying major cost drivers such as displaced time and opportunity costs, this research provides a comprehensive understanding of the multifaceted economic impacts of suicide.

The findings will inform data-driven policymaking and guide resource allocation for public health funding in suicide prevention efforts. Dissemination plans include peer-reviewed journal publications, with all data anonymized and stored in adherence to ethical guidelines.

 
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