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CTRI Number  CTRI/2025/02/080211 [Registered on: 10/02/2025] Trial Registered Prospectively
Last Modified On: 29/03/2026
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   Follow Up Study 
Study Design  Single Arm Study 
Public Title of Study   Oral Cancer Screening  
Scientific Title of Study   Effectiveness of Targeted Oral Cancer Screening Programs in Young Adults  
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  DrBhavna Joshi 
Designation  Professor 
Affiliation  Indian Institute of Ayurveda Research and hospital  
Address  Department of Shalakya tantra, IIARH- Rajkot GUJARAT India

Rajkot
GUJARAT
360110
India 
Phone  9825314997  
Fax    
Email  drbhavnajoshi@yahoo.com   
 
Details of Contact Person
Scientific Query
 
Name  DrBhavna Joshi 
Designation  Professor 
Affiliation  Indian Institute of Ayurveda Research and hospital  
Address  Department of Shalakya tantra, IIARH- Rajkot GUJARAT India

Rajkot
GUJARAT
360110
India 
Phone  9825314997  
Fax    
Email  drbhavnajoshi@yahoo.com   
 
Details of Contact Person
Public Query
 
Name  DrBhavna Joshi 
Designation  Professor 
Affiliation  Indian Institute of Ayurveda Research and hospital  
Address  Department of Shalakya tantra, IIARH- Rajkot GUJARAT India

Rajkot
GUJARAT
360110
India 
Phone  9825314997  
Fax    
Email  drbhavnajoshi@yahoo.com   
 
Source of Monetary or Material Support  
Indian instiute of ayurveda research and hospital kalawad road iswaria village Rajkot 361006 Gujarat India 
 
Primary Sponsor  
Name  Indian Institute of Ayurveda Research and Hospital (IIARH), Rajkot, Gujarat, India. 
Address  ishvaria,kalawad road,rajkot 
Type of Sponsor  Other [Private Ayurveda College] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Bhavna Joshi  Indian Institute of Ayurveda Research and Hospital (IIARH)  Department of Shalakya tantra Indian institute of ayurveda research and hospital Ishvaria Village Kalawad Road Rajkot
Rajkot
GUJARAT 
9825314997

drbhavnajoshi@yahoo.com 
 
Details of Ethics Committee
Modification(s)  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Independent Ethics Committee Indian Institute of Ayurveda Research and Hospital   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Oral Cancer Screening in Young Adults 
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
 
Inclusion Criteria  
Age From  17.00 Year(s)
Age To  35.00 Year(s)
Gender  Both 
Details  Individuals aged 17–35 years.
Residents of Rajkot willing to participate in cancer screening programs.
Participants able to provide informed consent.
 
 
ExclusionCriteria 
Details  Individuals with previously diagnosed cancers or currently undergoing treatment.
Participants unwilling or unable to complete the screening or surveys.
Individuals with medical conditions that contraindicate participation in the study.
 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
Identification and prevalence of cancer risk factors like tobacco use obesity and lifestyle habits among young adults aged 17 to 35 years in Rajkot.
Early detection of precancerous lesions or oral cancers in the screened population.
Awareness and acceptance levels of cancer screening programs in the targeted demographic.
 
one year 
 
Secondary Outcome  
Outcome  TimePoints 
Evaluation of participation rates in targeted oral cancer screening programs.
Recommendations for scaling & optimizing cancer screening initiatives tailored for young adults.
Assessment of the impact of awareness programs on lifestyle modifications & health-seeking behavior.
 
one year 
 
Target Sample Size   Total Sample Size="200"
Sample Size from India="200" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   10/03/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  
Not Applicable 
Recruitment Status of Trial (India)  Closed to Recruitment of Participants 
Publication Details
Modification(s)  
N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  

Summery

This study highlights important findings regarding cancer risk factors, awareness, and screening participation among young adults (18–35 years) in Rajkot.

A notable proportion of participants showed risk factors such as tobacco use (20%), unhealthy diet, sedentary lifestyle, and low physical activity, along with 21% reporting a family history of cancer. Despite moderate awareness of screening programs (63.5%), actual participation was very low (21%), with only 5% undergoing formal screening. Major barriers included lack of awareness, fear, limited access, and financial constraints.

Awareness of cancer treatment and diagnostic methods was moderate but varied with age and exposure to healthcare information. Importantly, better knowledge was linked to a higher willingness to quit tobacco. While many participants recognized early symptoms of oral cancer, gaps in knowledge about asymptomatic cases and diagnostic tests were evident, affecting early detection.

To improve screening uptake, key strategies include increasing awareness through social media and education, improving accessibility via workplaces and institutions, offering affordable screening, providing proper counselling, and reducing stigma.

Overall, the study emphasizes the urgent need for targeted, youth-focused cancer prevention and screening initiatives to reduce modifiable risks and promote early detection.

 
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