This is an in-vivo, randomized parallel group, three-arm clinical study evaluating the effectiveness of Photobiomodulation, Cryo- Anaesthesia and Topical Anaesthesia Gel in reduction of pain perception during local anaesthesia administration in children aged 8-12 years. The study will be conducted at the Department of Pediatric and Preventive Dentistry, KAHER’s KLE Vishwanath Katti Institute of Dental Sciences, Belagavi, and will include 48 children requiring dental treatment under the inferior alveolar nerve block anaesthesia technique. The principal investigator will perform the procedure under standard operating protocols. The selected child will be made to sit comfortably on the dental chair, the procedure will be completely explained to the parent as well as the child by the principal investigator. A case history will be recorded for the present study so as to have a systematic and methodological recording of all the observations and information. After recording the preliminary information, clinical examination will be carried out on a dental chair under standard operating protocol. Patients allocated to Group I will be treated with Photobiomodulation, Group II with Cryo-Anaesthesia, and Group III with Topical Anaesthesia Gel. The procedure will be carried out in approximately 5 minutes for each patient in all the three followed by the administration of local anaesthesia. Objective pain will be assessed by a trained pediatric dentist, who will be blinded during the intervention, using Sound, Eye, Body Movement (SEM) Scale during local anaesthesia administration. Subjective pain will be assessed using self-administered Wong–Baker Faces Pain Rating Scale immediately after local anaesthesia administration. Further necessary dental treatment will be provided following standard operating protocols.