The relevance of this study is to evaluate the common yet neglected aspect of having a digestive system disorder and how it affects one’s quality of life. Pancreatic insufficiency, lactose intolerance, and irritable bowel syndrome (IBS), conditions that prevent the secretion of certain enzymes, result in symptoms such as heartburn, bloating, constipation, and diarrhea. Although these symptoms are commonly experienced, many people disregard timely intervention leading to residual discomfort in the gastrointestinal system. The current treatment options rely heavily on medication, which may deter individuals from using them due to the severe side effects. Additionally, these treatments are not suitable for extended use. Therefore, there are acceptable substitutes that are safer to use and can be taken for producing effective results that further improve digestive activity. A combination of enzyme and probiotic supplementation is one such technique that has the potential to improve digestion. This enhances nutrient absorption, relief from nervous system symptoms, and maintain an overall improvement of gastrointestinal issues. This study seeks to assess the effectiveness of DigeSEB Super PB formulation with the addition of digestive enzymes and probiotic supplements in relieving digestive symptoms among adults with mild to moderate digestive distress. By assessing the strength and efficacy of this formulation, the study contributes toward the development of safe and effective interventions that are not involving drugs targeting digestive health. This method would be advantageous for addressing issues of impaired digestion and exacerbating existing gastrointestinal disorders.