FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2025/03/082244 [Registered on: 12/03/2025] Trial Registered Prospectively
Last Modified On: 07/03/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Comparing Effect of Integrated Neuromuscular Inhibition Technique Versus Local Vibration in treatment of Knee Osteoarthritis.  
Scientific Title of Study   Comparing the effectiveness of Integrated Neuromuscular Inhibition Technique Versus Local Vibration on Iliotibial Band Tightness as an adjunct in treatment of Knee Osteoarthritis. 
Trial Acronym  nil 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  RUCHIRA PRAKASH PATIL 
Designation  MPT STUDENT 
Affiliation  Sunandan Divatia School of Science 
Address  Department of Physiotherapy Ground floor, Nanavati Max Super Speciality Hospital Swami Vivekananda Rd, next to Suresh Colony LIC Colony Vile Parle West
Sunandan Divatia School of Science Bhaktivedanta Rd vile parle west Mumbai
Mumbai
MAHARASHTRA
400056
India 
Phone  8767291859  
Fax    
Email  ruchiraphysio2000@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Arnaaz Doctor 
Designation  Assistant Professor 
Affiliation  Sunandan Divatia School of Science 
Address  Sunandan Divatia School of Science, Department of Physiotherapy, 7th floor, Mithibai College Building, Bhaktivedanta Road, Vile Parle west

Mumbai
MAHARASHTRA
400056
India 
Phone  9930033014  
Fax    
Email  Arnaaz.Doctor@nmims.edu  
 
Details of Contact Person
Public Query
 
Name  Dr Arnaaz Doctor 
Designation  Assistant Professor 
Affiliation  Sunandan Divatia School of Science 
Address  Sunandan Divatia School of Science, Department of Physiotherapy, 7th floor, Mithibai College Building, Bhaktivedanta Road, Vile Parle west

Mumbai
MAHARASHTRA
400056
India 
Phone  9930033014  
Fax    
Email  Arnaaz.Doctor@nmims.edu  
 
Source of Monetary or Material Support  
Department of Physiotherapy, Ground floor, Nanavati Max Super Speciality Hospital Swami Vivekananda Rd, next to Suresh Colony LIC Colony Vile Parle West, Mumbai, MAHARASHTRA -400056, India 
 
Primary Sponsor  
Name  none 
Address  NA 
Type of Sponsor  Other [nil] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Ruchira Patil  Department of physiotherapy and Sports Medicine  Ground floor, Nanavati Max Super Speciality Hospital Swami Vivekananda Rd, next to Suresh Colony LIC Colony Vile Parle West -400056, India
Mumbai
MAHARASHTRA 
8767291859
-
ruchiraphysio2000@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Ethical Commitee, Dr Balabhai Nanavati Hospital  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M179||Osteoarthritis of knee, unspecified,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Integrated Neuromuscular Inhibition Technique (INIT)  The INIT techniques includes: • Ischemic compression (20 SEC) • Positional Release Technique (PRT)(20 SEC X 3 TIMES) • Muscle Energy Technique (Isometric Contraction held for 10 SEC X 3 TIMES), given along with convention exercises Dosage: 5 sessions/ week for 2 weeks 
Comparator Agent  Local vibration therapy   Local Vibration (Using Electric Fascial Gun for 2 mins), given along with conventional exercises Dosage: 5 session / week for 2 weeks 
 
Inclusion Criteria  
Age From  50.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  1) Patients having Osteoarthritis of knee (Grade 1 & 2 according to Kellgren-Lawrence Osteoarthritis Grading scale)
2) patients having Iliotibial Band tightness
 
 
ExclusionCriteria 
Details  1) Any musculoskeletal disorder or injury in past 6 months
2) Any major joint surgery
3) Any neuromuscular or cognitive disorder
 
 
Method of Generating Random Sequence   Random Number Table 
Method of Concealment   Alternation 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
1) VISUAL ANALOGUE SCALE (VAS)
2) TIMED UP AND GO TEST(TUG)
3) WOMAC (WESTERN ONTARIO MCMASTER UNIVERSITIED OSTEOARTHRITIS INDEX)
 
PRE AND POST INTERVENTION AFTER 2 WEEKS
 
 
Secondary Outcome  
Outcome  TimePoints 
1)OBERS TEST  PRE AND POST INTERVENTION AFTER 2 WEEKS 
 
Target Sample Size   Total Sample Size="46"
Sample Size from India="46" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   19/03/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Background and purpose of study:

Osteoarthritis (OA) is a degenerative joint condition causing cartilage loss, joint narrowing, and varus deformity, leading to iliotibial band (ITB) tightness, pain, and restricted mobility. Conventional treatments like stretching and strengthening offer relief, while emerging methods like vibration therapy and Integrated Neuromuscular Inhibition Technique (INIT) show promise. Vibration therapy reduces muscle tightness, whereas INIT combines ischemic compression, positional release, and isometric stretching. This study will compare the effectiveness of vibration therapy versus INIT on ITB tightness in knee OA using Ober’s Test, VAS, TUG, and WOMAC outcome measures.. The effectiveness of local vibration and integrated neuromuscular inhibition technique, is not well-established due to limited research. Hence, we intend to study and compare the effectiveness of these two techniques on ITB tightness in knee osteoarthritis



INTERVENTION:

GROUP A: Conventional exercise + Local Vibration

GROUP B: CONVENTIONAL exercises + INIT



CONVENTIONAL EXERCISES: 

WEEK 1:

1) Cryotherapy - 10 mins

2) Ankle toe movements & rotations - 10 reps

3) Statics (Quadriceps, Hamstrings, Glutes) - 5 sec hold x 10 reps

4) Vastus Medialis Oblique Strengthening - 5 sec hold x 10 reps

5) Hip Knee Flexion - 10 reps

6) Straight leg Abduction & Raises - 10 reps

7) Hip Clamps- 5 sec hold x 10 reps

8) Dynamic Quadriceps exercise –5 sec hold x 10 reps

9) Hamstrings stretching & TA – 30 sec each x 2reps



Week 2

10) Aerobic Straight leg raises-20 reps

11) Aerobic Straight leg abduction- 20 reps

12) Pelvic Bridging - 5 sec hold x 10 reps

13) Prone Hip Extension – 10 reps

14)  Heel and toe raises - 10 reps

15) One Leg Standing - 30 sec each leg

16) Mat walking ( forward, backward, sideways)

17) Stepping - 10 reps each leg

18) Cycling exercise 10 reps

 
Close