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CTRI Number  CTRI/2025/02/080612 [Registered on: 14/02/2025] Trial Registered Prospectively
Last Modified On: 17/01/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group, Active Controlled Trial 
Public Title of Study   Effect of Dynamic Joint Position Sense Exercises Versus Static Joint Position Sense Exercises in Joint Position on Unilateral Osteoarthritis Subjects 
Scientific Title of Study   Effectiveness of Dynamic Joint Position Sense (JPS) Exercises Versus Static Joint Position Sense Exercises in JPS on Unilateral Osteoarthritis Subjects 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  PRASANNA KUMAR R 
Designation  PG STUDENT 
Affiliation  SAVEETHA COLLEGE OF PHYSIOTHERAPY, SIMATS 
Address  Room no.A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu -602105 India

Kancheepuram
TAMIL NADU
602105
India 
Phone  9962702547  
Fax    
Email  prasannaram1809@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  K Kotteeswaran 
Designation  Professor 
Affiliation  Saveetha College of Physiotherpay 
Address  Room no.A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu -602105 India

Kancheepuram
TAMIL NADU
602105
India 
Phone  9894286700  
Fax    
Email  k.kotteeswaran@gmail.com  
 
Details of Contact Person
Public Query
 
Name  K Kotteeswaran 
Designation  Professor 
Affiliation  Saveetha College of Physiotherpay 
Address  Room no.A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu -602105 India

Kancheepuram
TAMIL NADU
602105
India 
Phone  9894286700  
Fax    
Email  k.kotteeswaran@gmail.com  
 
Source of Monetary or Material Support  
Room no.A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu- 602105  
 
Primary Sponsor  
Name  Prasanna Kumar R 
Address  Room no.A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu- 602105 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr K Kotteeswaran  Saveetha Hospital  Room No. A5, 5th floor, Health Science block, Saveetha college of Physiotherapy, Saveetha nagar, Thandalam, Kancheepuram, Tamil Nadu 602501
Kancheepuram
TAMIL NADU 
9894286700

k.kotteeswaran@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
INSTITUTIONAL SCIENTIFIC REVIEW BOARD  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M171||Unilateral primary osteoarthritisof knee,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Dynamic Joint Position Sense Exercises  One leg balance Blind advanced one leg balance Cross body leg swing Toe walking Duration 6 weeks 3 days a week 10-15 reps 3 sets 
Comparator Agent  Static Joint Proprioceptive Exercises  Pelvic bridging Unilateral pelvic bridging Mini squat Single limb mini squat Duration 6 weeks 3 days a week 10-15 reps 3 sets 
 
Inclusion Criteria  
Age From  45.00 Year(s)
Age To  78.00 Year(s)
Gender  Both 
Details  primary unilateral osteoarthritis of knee
45 to 78 yrs age group
both male and female 
 
ExclusionCriteria 
Details  Patients with complaints in one or more joint Polyarthritis
Presence of rheumatoid arthritis or other systemic inflammatory arthropathies
Knee arthroplasty surgery case
Intraarticular corticosteroid injection into either knee within the previous 3 months 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Participant, Investigator and Outcome Assessor Blinded 
Primary Outcome  
Outcome  TimePoints 
Range of motion  6 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
Error Angle  6 weeks 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   25/02/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="1"
Days="15" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Osteoarthritis (OA) is a common, all-encompassing illness that mostly affects the knee.       Osteoarthritis (OA) is a multifactorial disease that progresses over time and causes joint constriction and loss of articular cartilage in addition to pain, functional impairment, and physical disability, all of which significantly lower quality of life. In addition to pain, knee OA patients also experience muscle weakness, instability, exhaustion, and stiffness in morning. Dehydration and the deterioration of intraarticular and periarticular structures are pathophysiological alterations associated with osteoarthritis (OA). This, in turn, induces mechanoreceptor distraction, which results in a reduction in both static and dynamic kinaesthetic sensibility. Since limitations of stability, postural control, and knee proprioception are important variables that can greatly contribute to impairment, disability, and falls in people with KOA It has been demonstrated that using manual interventions, exercise therapy, and electrotherapy alone or in combination can improve proprioception and balance in physiotherapy treatments. Therefore, it may be necessary to use specific strategies, such as proprioceptive training, to tailor the therapeutic program for patients with osteoarthritis. Recent research indicates that proprioceptive training enhances muscle strength, balance, static and dynamic posture, and everyday function. The need for this study is to identify the research gap in order to find how dynamic JPS and static JPS exercise helps to improve balance and joint position sense in unilateral knee osteoarthritis.

 
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